Professor | Yunjiao He | Asia Growth Partners

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Name	Yunjiao He
Contact Information	heyj@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Yunjiao He

Contact Information

heyj@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Medical School
Academic Background & Achievements	1999-2003 Bachelor in Pharmacy: Wuhan University 2003-2006 Master in Pharmaceutical Chemistry: Wuhan University 2009-2013 PhD in Biochemistry and Molecular Biology: Hong Kong Polytechnic University
Work Experience	2006.07-2008.08 - Shanghai PharmaTech Co., Ltd - Drug Synthesis Researcher 2013.10-2014.07 - Hong Kong Polytechnic University, Research Assistant 2014.07-2016.07 - Hong Kong Polytechnic University, Postdoctoral Fellow 2016.09-2019.05 - Southern University of Science and Technology, Postdoctoral Fellow

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Medical School

Academic Background & Achievements

1999-2003 Bachelor in Pharmacy: Wuhan University
2003-2006 Master in Pharmaceutical Chemistry: Wuhan University
2009-2013 PhD in Biochemistry and Molecular Biology: Hong Kong Polytechnic University

Work Experience

2006.07-2008.08 - Shanghai PharmaTech Co., Ltd - Drug Synthesis Researcher
2013.10-2014.07 - Hong Kong Polytechnic University, Research Assistant
2014.07-2016.07 - Hong Kong Polytechnic University, Postdoctoral Fellow
2016.09-2019.05 - Southern University of Science and Technology, Postdoctoral Fellow

Areas of Focus	Structural Biology Glycochemistry
Publications	Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking, Shuai Wu, Yunjiao He, et al., 2018 Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C beta-Lactamases, Xuehua Pan, Yunjiao He, et al., 2017 Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis, Xuehua Pan, Yunjiao He, et al., 2017 Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation, Xuehua Pan, Yunjiao He, et al., 2014 A general and facile synthetic approach to N-alpha-Boc ureidoalanine derivatives, Teng H., Yunjiao He, et al., 2006 Novel intermediates in the active site of Class A β-lactamase reveal critical factors that coordinate the catalytic water molecule for nucleophilic attack on β-lactam acyl adduct, Yun jiao He, et al., 2019

Areas of Focus

Structural Biology
Glycochemistry

Publications

Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking, Shuai Wu, Yunjiao He, et al., 2018
Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C beta-Lactamases, Xuehua Pan, Yunjiao He, et al., 2017
Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis, Xuehua Pan, Yunjiao He, et al., 2017
Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation, Xuehua Pan, Yunjiao He, et al., 2014
A general and facile synthetic approach to N-alpha-Boc ureidoalanine derivatives, Teng H., Yunjiao He, et al., 2006
Novel intermediates in the active site of Class A β-lactamase reveal critical factors that coordinate the catalytic water molecule for nucleophilic attack on β-lactam acyl adduct, Yun jiao He, et al., 2019

Protein Structure Enzyme Mechanisms Molecular Interaction Biological Systems X-Ray Crystallography Nmr Spectroscopy Computational Modeling Bioinformatics Molecular Dynamics Drug Design

Yunjiao He - Southern University of Science and Technology

Hualiang Jiang - University of Chinese Academy of Sciences

Xiaomin Luo - University of Chinese Academy of Sciences

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