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Yan Li
liy33@sustech.edu.cn
Chinese, English
Guangdong
Southern University of Science and Technology
Life Sciences
  • 2008-2012 PhD: University of Hong Kong, Clinical Oncology
  • 2004-2008 Bachelor: Sun Yat-sen University, Biotechnology
  • Published over ten high-level papers in the past five years, including in journals like Nature Medicine and Gastroenterology
  • 2016-Present - Southern University of Science and Technology, Department of Biology - Assistant Professor
  • 2013-2016 - University of Hong Kong, Department of Clinical Oncology - Postdoctoral Research Fellow
  • 2014: Ministry of Education Natural Science Second Prize, Fourth Contributor
  • 2014: Li Ka Shing Faculty of Medicine, HKU, Outstanding Research Award
  • 2013: Hong Kong Young Scientist Award (Life Science), Hong Kong Science Society
  • 2013: Dr KP Stephen Chang Gold Medal, Li Ka Shing Faculty of Medicine, HKU
  • 2012: Li Ka Shing Prize, HKU
  • 2007: Sun Yat-sen University Pu Zhe Long Scholars Science Fund Award
Molecular genetics and epigenetics of human malignant tumors
Gene discovery related to liver cancer, esophageal cancer, and gastric cancer
Role of RNA editing in tumor development
Identification of cancer stem cells and their regulatory mechanisms
  • HBP21, a chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma, Jiang L, Kwong DL, Li Y, Liu M, Yuan YF, Li Y, Fu L, Guan XY, 2015
  • Loss of ATOH8 increases stem cell features of hepatocellular carcinoma cells, Song Y, Pan G, Chen L, Ma S, Zeng T, Chan HM, Li L, Lian Q, Chow R, Cai X, Li Y, Li Y, Liu M, Li Y, Zhu Y, Wong N, Yuan YF, Pei D, Guan XY, 2015
  • Hepatocellular Carcinoma: Transcriptome diversity regulated by RNA editing, Li Y, Chen L, Chan TH, Guan XY, 2013
  • Recoding RNA editing of antizyme inhibitor 1 predisposes to hepatocellular carcinoma, Chen LL, Li Y, Chi HL, Liu M, Song YY, Chan TH, Yuan YF, Chow RKK, Fu L, Kong KL, Zhang N, Tong AHY, Kwong DLW, Man K, Lo CM, Lok S, Tenen DG, Guan XY, 2013
  • SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice, Li Y, Chen LL, Chan TH, Liu M, Kong KL, Li Y, Qiu JL, Yuan YF, Guan XY, 2013
  • Allele-specific imbalance of oxidative stress-induced growth inhibitor 1 associates with progression of hepatocellular carcinoma, Liu M, Li Y, Chen L, Chan TH, Song Y, Fu L, Zeng TT, Dai YD, Zhu YH, Li Y, Chen J, Yuan YF, Guan XY, 2014
  • Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition via Akt/GSK-3β/Snail signaling, Liu L, Dai Y, Chen J, Zeng T, Li Y, Chen L, Zhu YH, Li J, Li Y, Xie D, Yuan YF, Guan XY, 2014
  • A disrupted RNA editing balance mediated by ADARs in human hepatocellular carcinoma, Chan TH, Lin CH, Qi L, Fei J, Li Y, Yong KJ, Liu M, Song Y, Chow RK, Ng VH, Yuan YF, Tenen DG, Guan XY, Chen L, 2014
  • Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma, Liu M, Chen LL, Chan TH, Wang J, Li Y, Li Y, Zeng TT, Yuan YF, Guan XY, 2012
  • MicroRNA-375 inhibits tumor growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor, Kong KL, Kwong DL, Chan TH, Law SY, Chen L, Li Y, Qin YR, Guan XY, 2012
  • Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression, Li J, Lau GK, Chen L, Dong SS, Lan HY, Huang XR, Li Y, Luk JM, Yuan YF, Guan XY, 2011
  • Overexpression of EIF5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma, Tang DJ, Dong SS, Ma NF, Xie D, Chen LL, Fu L, Lau SH, Li Y, Li Y, Guan XY, 2010
Molecular Genetics Epigenetics Tumors Liver Cancer Esophageal Cancer Gastric Cancer Rna Editing Tumor Development Cancer Stem Cells Regulatory Mechanisms

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