Professor | 李妍 | 数字化转型顾问

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Name	李妍
Contact Information	liy33@sustech.edu.cn
Language ability	中文, 英语
Province	广东省

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Name

李妍

Contact Information

liy33@sustech.edu.cn

Language ability

中文, 英语

Province

广东省

University/Lab Affiliation and Title	南方科技大学
Faculty	Life Sciences
Academic Background & Achievements	2008-2012 博士: 香港大学, 临床肿瘤系 2004-2008 学士: 中山大学, 生物技术专业近五年在SCI收录的国际杂志上发表高水平论文十余篇，包括Nature Medicine、Gastroenterology等杂志
Work Experience	2016年—至今，南方科技大学生物系助理教授 2013年-2016年，香港大学临床肿瘤系博士后研究员
Awards	2014年教育部自然科学二等奖，第四完成人 2014年香港大学李嘉诚医学院杰出研究成果奖 2013年香港科学会2013香港青年科学家奖（生命科学组） 2013年香港大学李嘉诚医学院Dr KP Stephen Chang Gold Medal 2012年香港大学李嘉诚奖 2007年中山大学蒲蜇龙学者科学基金奖

University/Lab Affiliation and Title

南方科技大学

Faculty

Life Sciences

Academic Background & Achievements

2008-2012 博士: 香港大学, 临床肿瘤系
2004-2008 学士: 中山大学, 生物技术专业
近五年在SCI收录的国际杂志上发表高水平论文十余篇，包括Nature Medicine、Gastroenterology等杂志

Work Experience

2016年—至今，南方科技大学生物系助理教授
2013年-2016年，香港大学临床肿瘤系博士后研究员

Awards

2014年教育部自然科学二等奖，第四完成人
2014年香港大学李嘉诚医学院杰出研究成果奖
2013年香港科学会2013香港青年科学家奖（生命科学组）
2013年香港大学李嘉诚医学院Dr KP Stephen Chang Gold Medal
2012年香港大学李嘉诚奖
2007年中山大学蒲蜇龙学者科学基金奖

Areas of Focus	人类恶性肿瘤的分子遗传学与表观遗传学与肝癌、食道癌及胃癌发生相关的基因发现 RNA编辑在肿瘤发生发展中的作用肿瘤干细胞及其干性调控机制的鉴定
Publications	HBP21, a chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma, Jiang L, Kwong DL, Li Y, Liu M, Yuan YF, Li Y, Fu L, Guan XY, 2015 Loss of ATOH8 increases stem cell features of hepatocellular carcinoma cells, Song Y, Pan G, Chen L, Ma S, Zeng T, Chan HM, Li L, Lian Q, Chow R, Cai X, Li Y, Li Y, Liu M, Li Y, Zhu Y, Wong N, Yuan YF, Pei D, Guan XY, 2015 Hepatocellular Carcinoma: Transcriptome diversity regulated by RNA editing, Li Y, Chen L, Chan TH, Guan XY, 2013 Recoding RNA editing of antizyme inhibitor 1 predisposes to hepatocellular carcinoma, Chen LL, Li Y, Chi HL, Liu M, Song YY, Chan TH, Yuan YF, Chow RKK, Fu L, Kong KL, Zhang N, Tong AHY, Kwong DLW, Man K, Lo CM, Lok S, Tenen DG, Guan XY, 2013 SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice, Li Y, Chen LL, Chan TH, Liu M, Kong KL, Li Y, Qiu JL, Yuan YF, Guan XY, 2013 Allele-specific imbalance of oxidative stress-induced growth inhibitor 1 associates with progression of hepatocellular carcinoma, Liu M, Li Y, Chen L, Chan TH, Song Y, Fu L, Zeng TT, Dai YD, Zhu YH, Li Y, Chen J, Yuan YF, Guan XY, 2014 Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition via Akt/GSK-3β/Snail signaling, Liu L, Dai Y, Chen J, Zeng T, Li Y, Chen L, Zhu YH, Li J, Li Y, Xie D, Yuan YF, Guan XY, 2014 A disrupted RNA editing balance mediated by ADARs in human hepatocellular carcinoma, Chan TH, Lin CH, Qi L, Fei J, Li Y, Yong KJ, Liu M, Song Y, Chow RK, Ng VH, Yuan YF, Tenen DG, Guan XY, Chen L, 2014 Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma, Liu M, Chen LL, Chan TH, Wang J, Li Y, Li Y, Zeng TT, Yuan YF, Guan XY, 2012 MicroRNA-375 inhibits tumor growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor, Kong KL, Kwong DL, Chan TH, Law SY, Chen L, Li Y, Qin YR, Guan XY, 2012 Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression, Li J, Lau GK, Chen L, Dong SS, Lan HY, Huang XR, Li Y, Luk JM, Yuan YF, Guan XY, 2011 Overexpression of EIF5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma, Tang DJ, Dong SS, Ma NF, Xie D, Chen LL, Fu L, Lau SH, Li Y, Li Y, Guan XY, 2010

Areas of Focus

人类恶性肿瘤的分子遗传学与表观遗传学
与肝癌、食道癌及胃癌发生相关的基因发现
RNA编辑在肿瘤发生发展中的作用
肿瘤干细胞及其干性调控机制的鉴定

Publications

HBP21, a chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma, Jiang L, Kwong DL, Li Y, Liu M, Yuan YF, Li Y, Fu L, Guan XY, 2015
Loss of ATOH8 increases stem cell features of hepatocellular carcinoma cells, Song Y, Pan G, Chen L, Ma S, Zeng T, Chan HM, Li L, Lian Q, Chow R, Cai X, Li Y, Li Y, Liu M, Li Y, Zhu Y, Wong N, Yuan YF, Pei D, Guan XY, 2015
Hepatocellular Carcinoma: Transcriptome diversity regulated by RNA editing, Li Y, Chen L, Chan TH, Guan XY, 2013
Recoding RNA editing of antizyme inhibitor 1 predisposes to hepatocellular carcinoma, Chen LL, Li Y, Chi HL, Liu M, Song YY, Chan TH, Yuan YF, Chow RKK, Fu L, Kong KL, Zhang N, Tong AHY, Kwong DLW, Man K, Lo CM, Lok S, Tenen DG, Guan XY, 2013
SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice, Li Y, Chen LL, Chan TH, Liu M, Kong KL, Li Y, Qiu JL, Yuan YF, Guan XY, 2013
Allele-specific imbalance of oxidative stress-induced growth inhibitor 1 associates with progression of hepatocellular carcinoma, Liu M, Li Y, Chen L, Chan TH, Song Y, Fu L, Zeng TT, Dai YD, Zhu YH, Li Y, Chen J, Yuan YF, Guan XY, 2014
Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition via Akt/GSK-3β/Snail signaling, Liu L, Dai Y, Chen J, Zeng T, Li Y, Chen L, Zhu YH, Li J, Li Y, Xie D, Yuan YF, Guan XY, 2014
A disrupted RNA editing balance mediated by ADARs in human hepatocellular carcinoma, Chan TH, Lin CH, Qi L, Fei J, Li Y, Yong KJ, Liu M, Song Y, Chow RK, Ng VH, Yuan YF, Tenen DG, Guan XY, Chen L, 2014
Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma, Liu M, Chen LL, Chan TH, Wang J, Li Y, Li Y, Zeng TT, Yuan YF, Guan XY, 2012
MicroRNA-375 inhibits tumor growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor, Kong KL, Kwong DL, Chan TH, Law SY, Chen L, Li Y, Qin YR, Guan XY, 2012
Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression, Li J, Lau GK, Chen L, Dong SS, Lan HY, Huang XR, Li Y, Luk JM, Yuan YF, Guan XY, 2011
Overexpression of EIF5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma, Tang DJ, Dong SS, Ma NF, Xie D, Chen LL, Fu L, Lau SH, Li Y, Li Y, Guan XY, 2010

分子遗传学表观遗传学肿瘤肝癌食道癌胃癌 Rna编辑肿瘤发展癌症干细胞调控机制

杨小飞 - 中国科学院大学

蔡雷 - 上海交通大学

陆青 - 上海交通大学

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