Upload Avatar (500 x 500)
Ou Xijun
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, English
B-Cell
Rna
Splicing
Modification
Antibody Response
Immune Memory
Development
Mechanism
Regulation
Research
Areas of Focus
- B-cell RNA Regulation
Work Experience
- 2023-Present: Southern University of Science and Technology, Department of Basic Immunology and Microbiology, Associate Professor (Tenured)
- 2022-2023: Southern University of Science and Technology, Department of Basic Immunology and Microbiology, Assistant Professor (Tenure-track)
- 2016-2022: Southern University of Science and Technology, Department of Biology, Assistant Professor (Tenure-track)
- 2009-2016: Bioprocessing Technology Institute, Singapore, Postdoctoral Researcher
Academic Background & Achievements
- 2001 - Bachelor in Microbiology: Huazhong Agricultural University
- 2009 - PhD in Microbiology: Fudan University
- Key mechanism in B-cell CD40 variable splicing regulation discovered
Publications
- The RNA-binding protein hnRNP F is required for the germinal center B cell response, Huang H, Li Y, Zhang G, Ruan GX, Zhu Z, Chen W, Zou J, Zhang R, Wang J, Ouyang Y, Xu S*, Ou X*, 2023
- Adenosine deaminase acting on RNA-1 is essential for early B-lymphopoiesis, Chen W, Li Y, Ruan GX, Huang H, Zhang R, Wang J, Ouyang Y, Li Y, Xu S*, Ou X*, 2022
- RNA-editing enzyme ADAR1 p150 isoform is critical for germinal centre B cell response, Li Y, Ruan GX, Chen W, Huang H, Zhang R, Wang J, Li Y*, Xu S, Ou X*, 2022
- Mettl14-mediated m6A modification is essential for germinal centre B cell response, Huang H, Zhang G, Ruan GX, Li Y, Chen W, Zhou J, Zhang R, Wang J, Ji SJ*, Xu S, Ou X*, 2022
- The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement, Ruan GX, Li Y, Chen W, Huang H, Zhang R, Chen C, Lam KP, Xu S, Ou X*, 2022
