Areas of Focus
- Structural analysis of amyloid fibrils using cryo-EM
- Design of inhibitors based on structure for fibrosis
- Drug development for Alzheimer's disease based on interactions of Aβ with its natural receptors
Work Experience
- 2019-2021 - University of California, Los Angeles - Assistant Researcher
- 2013-2019 - University of California, Los Angeles - Postdoctoral Researcher
Academic Background & Achievements
- 2008-2013 PhD in Biochemistry and Molecular Biology, Peking University
- 2013-2019 Postdoctoral Researcher, University of California, Los Angeles
- 2019-2021 Assistant Researcher, University of California, Los Angeles
- Youth Chief Scientist in National Key R&D Program of China
Publications
- Serine peptidase Vpr forms enzymatically active fibrils outside Bacillus bacteria revealed by cryo-EM, Cheng, Y., Han, J., Song, M., Zhang S., Cao, Q#., 2023
- Amyloid fibrils in disease FTLD-TDP are composed of TMEM106B not TDP-43, Jiang, Y. X., Cao, Q., Sawaya, M. R., Abskharon, R., Ge, P., DeTure, M., Dickson, D. W., Fu, J. Y., Loo, R. R. O., Loo, J. A., Eisenberg, D. S., 2022