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Haifeng Chen
Life Science
Shanghai Jiao Tong University
Shanghai
Language: English, Chinese, French
Molecular Dynamics
Force Fields
Disordered Proteins
Protein Structure
High-Performance Computing
Simulation
Bioinformatics
Drug Design
Artificial Intelligence
Disease Research
Areas of Focus
- Precision molecular force fields for intrinsically disordered proteins
- AI-based novel protein design
- Computer-assisted innovative drug discovery
Work Experience
- 2013–Present: Associate Editor, Chemical Biology & Drug Design
- 2015–Present: Associate Editor, Frontiers in Molecular Biosciences
- 2022–Present: Editorial Board Member, Journal of Chemical Information and Modeling
- 2022–Present: Editorial Board Member, International Journal of Molecular Sciences
- 2023–Present: Committee Member, Bioinformatics Society on Biomolecular Structure Prediction and Simulation
- 2024–Present: Director, Shanghai Bioinformatics Society
Academic Background & Achievements
- Bachelor's Degree: Xi'an Jiaotong University
- Master's Degree: Sichuan University
- PhD: University of Paris VII
- Postdoctoral Research: University of California, Irvine
- Published over 160 SCI papers
Publications
- Dynamical Important Residue Network (DIRN): Network Inference via Conformational Change, Q. Li, R. Luo*, H.F. Chen*, 2019
- Well-balanced Force Field ff03CMAP for Folded and Disordered Proteins, Y. Zhang, H. Liu, S. Yang, R. Luo*, H.F. Chen*, 2019
- The IDP-Specific Force Field ff14IDPSFF Improves the Conformer Sampling of Intrinsically Disordered Proteins, D. Song, R. Luo, H.F. Chen*, 2017
- ASD: a comprehensive database of allosteric proteins and modulators, Z. Huang, L. Zhu, Y. Cao, G. Wu, X. Liu, Y. Chen, Q. Wang, T. Shi, Y. Zhao, Y. Wang, W. Li, Y. Li, H.F. Chen*, G. Chen, J. Zhang*, 2011
- Rig-I regulates NF-κB activity through binding to Nf-κb13′-UTR mRNA, H. Zhang, Z. Liu, Y. Sun, J. Zhu, S. Lu, X. Liu, Q. Huang,Y. Xie, H. Zhu, S. Dang, H.F. Chen, G. Zheng, Y. Li, Y. Kuang, J. Fei, S. Chen, Z. Chen, Z.G. Wang*, 2013
- Binding induced folding in p53-MDM2 complex, H.F. Chen, R. Luo*, 2007
- PTMint Database of Experimentally Verified PTM Regulation on Protein-Protein Interaction, X. Hong, N. Li, J. Lv, Y. Zhang, J. Li*, J. Zhang*, H.F. Chen*, 2023
- Phanto-IDP: Compact Model for Precise Intrinsically Disordered Protein Backbone Generation and Enhanced Sampling, J.J. Zhu, Z. Li, H. Tong, Z. Lu, N. Zhang, T. Wei*, H.F. Chen*, 2024
- Balanced Three-point Water Model OPC3-B for Intrinsically Disordered and Ordered Proteins, Z. Pan, J. Mu, H.F. Chen*, 2023
- Graphormer Supervised De Novo Protein Design Method and Function Validation, J. Mu, Z. Li, B. Zhang, Q. Zhang, J. Iqbal, A. Wadood, T. Wei*, Y. Feng*, H.F. Chen*, 2024
Awards
- 2003: Shanghai Science and Technology Progress First Prize
- 2019: Shanghai Jiaotong University Teaching Achievement First Prize
- 2020: Shanghai Jiaotong University Teaching and Educating Third Prize
- 2022: National College Students' Life Science Innovation and Entrepreneurship Competition First Prize (Advisor)
- 2023: National College Students' Life Science Innovation and Entrepreneurship Competition First Prize (Advisor)
- 2023: Shanghai Challenge Cup First Prize (Advisor)
- 2015, 2022, 2023, 2024: Shanghai Jiaotong University Excellent Bachelor Thesis Advisor
