Professor | Haifeng Chen | Asia Growth Partners

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Name	Haifeng Chen
Contact Information	haifengchen@sjtu.edu.cn
Language ability	English, Chinese, French
Province	Shanghai

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Name

Haifeng Chen

Contact Information

haifengchen@sjtu.edu.cn

Language ability

English, Chinese, French

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	Bachelor's Degree: Xi'an Jiaotong University Master's Degree: Sichuan University PhD: University of Paris VII Postdoctoral Research: University of California, Irvine Published over 160 SCI papers
Work Experience	2013–Present: Associate Editor, Chemical Biology & Drug Design 2015–Present: Associate Editor, Frontiers in Molecular Biosciences 2022–Present: Editorial Board Member, Journal of Chemical Information and Modeling 2022–Present: Editorial Board Member, International Journal of Molecular Sciences 2023–Present: Committee Member, Bioinformatics Society on Biomolecular Structure Prediction and Simulation 2024–Present: Director, Shanghai Bioinformatics Society
Awards	2003: Shanghai Science and Technology Progress First Prize 2019: Shanghai Jiaotong University Teaching Achievement First Prize 2020: Shanghai Jiaotong University Teaching and Educating Third Prize 2022: National College Students' Life Science Innovation and Entrepreneurship Competition First Prize (Advisor) 2023: National College Students' Life Science Innovation and Entrepreneurship Competition First Prize (Advisor) 2023: Shanghai Challenge Cup First Prize (Advisor) 2015, 2022, 2023, 2024: Shanghai Jiaotong University Excellent Bachelor Thesis Advisor

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

Bachelor's Degree: Xi'an Jiaotong University
Master's Degree: Sichuan University
PhD: University of Paris VII
Postdoctoral Research: University of California, Irvine
Published over 160 SCI papers

Work Experience

2013–Present: Associate Editor, Chemical Biology & Drug Design
2015–Present: Associate Editor, Frontiers in Molecular Biosciences
2022–Present: Editorial Board Member, Journal of Chemical Information and Modeling
2022–Present: Editorial Board Member, International Journal of Molecular Sciences
2023–Present: Committee Member, Bioinformatics Society on Biomolecular Structure Prediction and Simulation
2024–Present: Director, Shanghai Bioinformatics Society

Awards

2003: Shanghai Science and Technology Progress First Prize
2019: Shanghai Jiaotong University Teaching Achievement First Prize
2020: Shanghai Jiaotong University Teaching and Educating Third Prize
2022: National College Students' Life Science Innovation and Entrepreneurship Competition First Prize (Advisor)
2023: National College Students' Life Science Innovation and Entrepreneurship Competition First Prize (Advisor)
2023: Shanghai Challenge Cup First Prize (Advisor)
2015, 2022, 2023, 2024: Shanghai Jiaotong University Excellent Bachelor Thesis Advisor

Areas of Focus	Precision molecular force fields for intrinsically disordered proteins AI-based novel protein design Computer-assisted innovative drug discovery
Publications	Dynamical Important Residue Network (DIRN): Network Inference via Conformational Change, Q. Li, R. Luo, H.F. Chen, 2019 Well-balanced Force Field ff03CMAP for Folded and Disordered Proteins, Y. Zhang, H. Liu, S. Yang, R. Luo, H.F. Chen, 2019 The IDP-Specific Force Field ff14IDPSFF Improves the Conformer Sampling of Intrinsically Disordered Proteins, D. Song, R. Luo, H.F. Chen, 2017 ASD: a comprehensive database of allosteric proteins and modulators, Z. Huang, L. Zhu, Y. Cao, G. Wu, X. Liu, Y. Chen, Q. Wang, T. Shi, Y. Zhao, Y. Wang, W. Li, Y. Li, H.F. Chen, G. Chen, J. Zhang, 2011 Rig-I regulates NF-κB activity through binding to Nf-κb13′-UTR mRNA, H. Zhang, Z. Liu, Y. Sun, J. Zhu, S. Lu, X. Liu, Q. Huang,Y. Xie, H. Zhu, S. Dang, H.F. Chen, G. Zheng, Y. Li, Y. Kuang, J. Fei, S. Chen, Z. Chen, Z.G. Wang, 2013 Binding induced folding in p53-MDM2 complex, H.F. Chen, R. Luo, 2007 PTMint Database of Experimentally Verified PTM Regulation on Protein-Protein Interaction, X. Hong, N. Li, J. Lv, Y. Zhang, J. Li, J. Zhang, H.F. Chen, 2023 Phanto-IDP: Compact Model for Precise Intrinsically Disordered Protein Backbone Generation and Enhanced Sampling, J.J. Zhu, Z. Li, H. Tong, Z. Lu, N. Zhang, T. Wei, H.F. Chen, 2024 Balanced Three-point Water Model OPC3-B for Intrinsically Disordered and Ordered Proteins, Z. Pan, J. Mu, H.F. Chen, 2023 Graphormer Supervised De Novo Protein Design Method and Function Validation, J. Mu, Z. Li, B. Zhang, Q. Zhang, J. Iqbal, A. Wadood, T. Wei, Y. Feng, H.F. Chen, 2024

Areas of Focus

Precision molecular force fields for intrinsically disordered proteins
AI-based novel protein design
Computer-assisted innovative drug discovery

Publications

Dynamical Important Residue Network (DIRN): Network Inference via Conformational Change, Q. Li, R. Luo*, H.F. Chen*, 2019
Well-balanced Force Field ff03CMAP for Folded and Disordered Proteins, Y. Zhang, H. Liu, S. Yang, R. Luo*, H.F. Chen*, 2019
The IDP-Specific Force Field ff14IDPSFF Improves the Conformer Sampling of Intrinsically Disordered Proteins, D. Song, R. Luo, H.F. Chen*, 2017
ASD: a comprehensive database of allosteric proteins and modulators, Z. Huang, L. Zhu, Y. Cao, G. Wu, X. Liu, Y. Chen, Q. Wang, T. Shi, Y. Zhao, Y. Wang, W. Li, Y. Li, H.F. Chen*, G. Chen, J. Zhang*, 2011
Rig-I regulates NF-κB activity through binding to Nf-κb13′-UTR mRNA, H. Zhang, Z. Liu, Y. Sun, J. Zhu, S. Lu, X. Liu, Q. Huang,Y. Xie, H. Zhu, S. Dang, H.F. Chen, G. Zheng, Y. Li, Y. Kuang, J. Fei, S. Chen, Z. Chen, Z.G. Wang*, 2013
Binding induced folding in p53-MDM2 complex, H.F. Chen, R. Luo*, 2007
PTMint Database of Experimentally Verified PTM Regulation on Protein-Protein Interaction, X. Hong, N. Li, J. Lv, Y. Zhang, J. Li*, J. Zhang*, H.F. Chen*, 2023
Phanto-IDP: Compact Model for Precise Intrinsically Disordered Protein Backbone Generation and Enhanced Sampling, J.J. Zhu, Z. Li, H. Tong, Z. Lu, N. Zhang, T. Wei*, H.F. Chen*, 2024
Balanced Three-point Water Model OPC3-B for Intrinsically Disordered and Ordered Proteins, Z. Pan, J. Mu, H.F. Chen*, 2023
Graphormer Supervised De Novo Protein Design Method and Function Validation, J. Mu, Z. Li, B. Zhang, Q. Zhang, J. Iqbal, A. Wadood, T. Wei*, Y. Feng*, H.F. Chen*, 2024

Molecular Dynamics Force Fields Disordered Proteins Protein Structure High-Performance Computing Simulation Bioinformatics Drug Design Artificial Intelligence Disease Research

Guohui Chuai - Tongji University

Qiansen Zhang - East China Normal University

Yudong Cai - Shanghai University

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