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Xiaofei Li
Life Science
Shanghai Jiao Tong University
Shanghai
Language: English, Chinese
Chronic Inflammation
Pathogenesis
Resolution Mechanisms
Comorbidities
Treatment Strategies
Hematopoietic Stem Cells
Trained Immunity
Epigenetic Regulation
Immune Cells
Tissue Homeostasis
Areas of Focus
- Pathogenesis and resolution mechanisms of chronic inflammation
- Pathogenesis and treatment strategies of chronic comorbidities
- Epigenetic regulation mechanisms in trained immunity of hematopoietic stem cells
Work Experience
- 2022-present: Associate Professor, School of Life Sciences and Technology, Shanghai Jiao Tong University
- 2015-2021: Postdoctoral Researcher, Department of Translational Medicine, University of Pennsylvania
Academic Background & Achievements
- 2010-2015: PhD in Pathogen Biology, Fudan University
- 2006-2010: Bachelor of Science in Biological Sciences, Henan University
Publications
- Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities, Xiaofei Li et al., 2022
- DEL-1 promotes macrophage efferocytosis and clearance of inflammation, Xiaofei Li et al., 2019
- The DEL-1/β3 integrin axis promotes regulatory T cell responses during inflammation resolution, Xiaofei Li et al., 2020
- Immunometabolic control of hematopoiesis, Xiaofei Li et al., 2021
- Innate immune training of granulopoiesis promotes anti-tumor activity, Xiaofei Li et al., 2020
- Stromal cell–derived DEL-1 inhibits Tfh cell activation and inflammatory arthritis, Xiaofei Li et al., 2021
- The secreted protein DEL-1 activates a β3 integrin–FAK–ERK1/2–RUNX2 pathway and promotes osteogenic differentiation and bone regeneration, Xiaofei Li et al., 2020
