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Zai Gao Tan
Life Science
Shanghai Jiao Tong University
Shanghai
Language: English, Chinese
Synthetic Biology
Metabolic Engineering
Microbial Chassis Cells
Stress Tolerance
Secondary Metabolites
Biocatalysis
Polyketides
Terpenes
Flavonoids
Isoprenoids
Areas of Focus
- Artificial synthesis pathways
- Microbial cell factory tolerance enhancement
Work Experience
- 2014-2016 Postdoctoral Researcher, Department of Chemical and Biological Engineering, Iowa State University
- 2016-2019 Postdoctoral Researcher, Departments of Chemistry and Biochemistry & Biosciences, Rice University
- 2019-present Group Leader and PhD Supervisor, Microbial Metabolism National Key Laboratory, Shanghai Jiao Tong University
Academic Background & Achievements
- 2008 Bachelor in Bioengineering, Shandong Agricultural University
- 2011 Master in Microbiology, Microbiology Technology National Key Laboratory, Shandong University
- 2014 PhD in Microbiology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences
Publications
- A non-carboxylative route for the efficient synthesis of central metabolite malonyl-CoA and its derived products, Zai Gao Tan, 2023
- Integration of (S)-2,3-oxidosqualene enables E. coli to become Iron Man E. coli with improved overall tolerance, Zai Gao Tan, 2023
- Designing artificial pathways for improving chemical production, Zai Gao Tan, 2023
- A polyketoacyl-CoA thiolase-dependent pathway for the synthesis of polyketide backbones, Zai Gao Tan, 2023
- The isoprenoid alcohol pathway, a synthetic route for isoprenoid biosynthesis, Zai Gao Tan, 2023
- Engineering of E. coli inherent fatty acid biosynthesis capacity to increase octanoic acid production, Zai Gao Tan, 2023
- Synthetic Pathway for the Production of Olivetolic Acid in Escherichia coli, Zai Gao Tan, 2023
- Engineering Escherichia coli Membrane Phospholipid Head Distribution Improves Tolerance and Production of Biorenewables, Zai Gao Tan, 2023
- Improving Escherichia coli membrane integrity and fatty acid production by expression tuning of FadL and OmpF, Zai Gao Tan, 2023
- Membrane Engineering via Trans Unsaturated Fatty Acids Production Improves Escherichia coli Robustness and Production of Biorenewables, Zai Gao Tan, 2023
