Professor | Zhijun Wang | Asia Growth Partners

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Name	Zhijun Wang
Contact Information	wangzhijun@sjtu.edu.cn
Language ability	Chinese, English
Province	Shanghai

Upload Avatar (500 x 500)

Name

Zhijun Wang

Contact Information

wangzhijun@sjtu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	Doctorate: Microbial Metabolism National Key Laboratory Position at Shanghai Jiao Tong University since 2007 Visiting Scholar at University of California, Berkeley (2011-2013)
Work Experience	2007 - Present - Shanghai Jiao Tong University, Microbial Metabolism National Key Laboratory

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

Doctorate: Microbial Metabolism National Key Laboratory
Position at Shanghai Jiao Tong University since 2007
Visiting Scholar at University of California, Berkeley (2011-2013)

Work Experience

2007 - Present - Shanghai Jiao Tong University, Microbial Metabolism National Key Laboratory

Areas of Focus	Synthetic machinery of natural products Cryo-EM techniques for protein structure analysis Synthetic machinery for antibiotics like erythromycin and penicillin Synthetic machinery for lovastatin and related compounds
Publications	C-N bond formation by a polyketide synthase, Wang J, Wang X, Li X, Kong L, Du Z, Li D, Gou L, Wu H, Cao W, Wang X, Lin S, Shi T, Deng Z, Wang Z, Liang J, 2023 Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain, Wang J, Li D, Chen L, Cao W, Kong L, Zhang W, Croll T, Deng Z, Liang J, Wang Z, 2022 Structural basis for the biosynthesis of Lovastatin, Wang J, Liang J, Chen L, Zhang W, Kong L, Peng C, Su C, Tang Y, Deng X, Wang Z, 2021 An in vitro DNA Phosphorothioate Modification Reaction, Pu T, Mei Z, Zhang W, Liang W, Zhou X, Liang J, Deng Z, Wang Z, 2020 Phosphorothioated DNA is shielded from oxidative damage, Pu T, Liang J, Mei Z, Yang Y, Wang J, Zhang W, Liang W, Zhou X, Deng Z, Wang Z, 2019 Recycling of Overactivated Acyls by a Type II Thioesterase during Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882, Wu H, Liang J, Gou L, Wu Q, Liang W, Zhou X, Bruce IJ, Deng Z, Wang Z, 2018 Cezomycin Is Activated by CalC to Its Ester Form for Further Biosynthesis Steps in the Production of Calcimycin in Streptomyces chartreusis NRRL 3882, Wu H, Liang J, Wang J, Liang W, Gou L, Wu Q, Zhou X, Bruce IJ, Deng Z, Wang Z, 2018 CRISPR/dCas9-Mediated Multiplex Gene Repression in Streptomyces, Zhao Y, Li L, Zheng G, Jiang W, Deng Z, Wang Z, Lu Y, 2018 Phosphorothioate DNA as an antioxidant in bacteria, Xie X, Liang J, Pu T, Xu F, Yao F, Yang Y, Zhao Y, You D, Zhou X, Deng Z, Wang Z, 2012 DNA modification by sulfur: analysis of the sequence recognition specificity surrounding the modification sites, Liang J, Wang Z, He X, Li J, Zhou X, Deng Z, 2007

Areas of Focus

Synthetic machinery of natural products
Cryo-EM techniques for protein structure analysis
Synthetic machinery for antibiotics like erythromycin and penicillin
Synthetic machinery for lovastatin and related compounds

Publications

C-N bond formation by a polyketide synthase, Wang J, Wang X, Li X, Kong L, Du Z, Li D, Gou L, Wu H, Cao W, Wang X, Lin S, Shi T, Deng Z, Wang Z, Liang J, 2023
Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain, Wang J, Li D, Chen L, Cao W, Kong L, Zhang W, Croll T, Deng Z, Liang J, Wang Z, 2022
Structural basis for the biosynthesis of Lovastatin, Wang J, Liang J, Chen L, Zhang W, Kong L, Peng C, Su C, Tang Y, Deng X, Wang Z, 2021
An in vitro DNA Phosphorothioate Modification Reaction, Pu T, Mei Z, Zhang W, Liang W, Zhou X, Liang J, Deng Z, Wang Z, 2020
Phosphorothioated DNA is shielded from oxidative damage, Pu T, Liang J, Mei Z, Yang Y, Wang J, Zhang W, Liang W, Zhou X, Deng Z, Wang Z, 2019
Recycling of Overactivated Acyls by a Type II Thioesterase during Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882, Wu H, Liang J, Gou L, Wu Q, Liang W, Zhou X, Bruce IJ, Deng Z, Wang Z, 2018
Cezomycin Is Activated by CalC to Its Ester Form for Further Biosynthesis Steps in the Production of Calcimycin in Streptomyces chartreusis NRRL 3882, Wu H, Liang J, Wang J, Liang W, Gou L, Wu Q, Zhou X, Bruce IJ, Deng Z, Wang Z, 2018
CRISPR/dCas9-Mediated Multiplex Gene Repression in Streptomyces, Zhao Y, Li L, Zheng G, Jiang W, Deng Z, Wang Z, Lu Y, 2018
Phosphorothioate DNA as an antioxidant in bacteria, Xie X, Liang J, Pu T, Xu F, Yao F, Yang Y, Zhao Y, You D, Zhou X, Deng Z, Wang Z, 2012
DNA modification by sulfur: analysis of the sequence recognition specificity surrounding the modification sites, Liang J, Wang Z, He X, Li J, Zhou X, Deng Z, 2007

Synthesis Natural Products Cryo-Em Protein Structure Antibiotics Erythromycin Penicillin Lovastatin Lipid-Lowering Drugs Cancer Treatment

Hua Yuan - Shanghai Normal University

Hongbo Hu - Shanghai Jiao Tong University

Shuangjun Lin - Shanghai Jiao Tong University

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