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Zhou Fan
Life Science
Tsinghua University
Beijing
Language: Chinese, English
Single-Cell
Multi-Omics
Lineage Specialization
Mammalian Development
Human Embryonic Development
In Vivo Models
In Vitro Models
Cell Fate Transitions
Embryo Implantation
Reproductive System Tumors
Areas of Focus
- Development of novel single-cell multi-omics analyses to decode lineage specialization in mammalian and human embryonic development
- Development of in vivo and in vitro models to understand the molecular mechanisms of cell fate transitions during embryonic development
- Exploration of regulatory mechanisms related to embryo implantation and the progression of reproductive system tumors
Work Experience
- 2020-present - Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor
- 2020-present - Tsinghua-Peking Life Science Joint Center - Researcher
Academic Background & Achievements
- 2005-2010 Bachelor: Datong University
- 2010-2016 PhD: Military Medical Science Academy
- 2016-2020 Postdoctoral Research: Peking University
Publications
- Cynomolgus monkey embryo model captures gastrulation and early pregnancy, Li J, Zhu Q, Cao J, Liu Y, Lu Y, Sun Y, Li Q, Huang Y, Shang S, Bian X, Li C, Zhang L, Wang Y, Nie Y, Fu J, Li W, Mazid MA, Jiang Y, Jia W, Wang X, Sun Y, Esteban MA, Sun Q, Zhou F, Liu Z, 2023
- Decoding Anterior-Posterior Axis Emergence among Mouse, Monkey, and Human Embryos, Zhu Q, Ge J, Liu Y, Xu J, Yan S, Zhou F, 2023
- Genomic Architecture of Cells in Tissues (GeACT): Study of Human Mid-gestation Fetus, Tian F, Zhou F, Li X, Ma W, Wu H, Yang M, Chapman AR, Lee DF, Tan L, Xing D, Yin G, Semayel A, Wang J, Wang J, Sun W, He R, Zhang S, Cao Z, Wei L, Lu S, Yang D, Mao Y, Gao Y, Chen K, Zhang Y, Liu X, Yong J, Yan L, Huang Y, Qiao J, Tang F, Gao G, Xie XS, 2020
- Reconstituting the transcriptome and DNA methylome landscapes of human implantation, Zhou F, Wang R, Yuan P, Ren Y, Mao Y, Li R, Lian Y, Li J, Wen L, Yan L, Qiao J, Tang F, 2019
- Tracing haematopoietic stem cell formation at single-cell resolution, Zhou F, Li X, Wang W, Zhu P, Zhou J, He W, Ding M, Xiong F, Zheng X, Li Z, Ni Y, Mu X, Wen L, Cheng T, Lan Y, Yuan W, Tang F, Liu B, 2016
- Generation of hematopoietic stem cells from purified embryonic endothelial cells by a simple and efficient strategy, Li Z, Zhou F, Chen D, He W, Ni Y, Luo L, Liu B, 2013
Awards
- 2019: Top Ten Advances in Life Sciences in China (Single-cell technology for human embryo implantation)
- 2017: Bayer Postdoctoral Award
- 2017: China Association for Science and Technology Youth Talent Lift Project
- 2016: Peking-Tsinghua Life Science Joint Center Postdoctoral Fund (Special)
- 2016: Wu Rui Scholarship
- 2016: National Excellent Doctoral Dissertation
