Professor | Li Pilong | Asia Growth Partners

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Name	Li Pilong
Contact Information	pilongli@mail.tsinghua.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Li Pilong

Contact Information

pilongli@mail.tsinghua.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Tsinghua University
Faculty	Life Sciences
Academic Background & Achievements	1996-2000 Bachelor: Peking University 2000-2002 Master: Hong Kong University of Science and Technology 2002-2009 PhD: University of Texas Southwestern Medical Center Postdoctoral Research: University of Texas Southwestern Medical Center, University of Pennsylvania
Work Experience	2016-present: Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor
Awards	Vice Chairman of the Biophysical Society of China on Biomolecular Phase Separation and Transition Editorial Board Member of Molecular Cell Associate Editor of Biochemical Journal Reviewer for journals like Cell, Nature, Science

University/Lab Affiliation and Title

Tsinghua University

Faculty

Life Sciences

Academic Background & Achievements

1996-2000 Bachelor: Peking University
2000-2002 Master: Hong Kong University of Science and Technology
2002-2009 PhD: University of Texas Southwestern Medical Center
Postdoctoral Research: University of Texas Southwestern Medical Center, University of Pennsylvania

Work Experience

2016-present: Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor

Awards

Vice Chairman of the Biophysical Society of China on Biomolecular Phase Separation and Transition
Editorial Board Member of Molecular Cell
Associate Editor of Biochemical Journal
Reviewer for journals like Cell, Nature, Science

Areas of Focus	Universal regulatory mechanisms and laws of phase separation phenomena Biological significance of phase separation in autophagy, transcriptional regulation, and epigenetics Technology development and applications based on phase separation
Publications	Dual-Role Transcription Factors Stabilize Intermediate Expression Levels, He J, Huo X, Pei G, Jia Z, Yan Y, Yu J, Qu H, Xie Y, Yuan J, Zheng Y, Hu Y, Shi M, You K, Li T, Ma T, Zhang M Q, Ding S, Li P, Li Y, 2024 An all-in-one targeted protein degradation platform guided by degradation condensates-bridging bi-specific nanobodies, Jia W, Li W, Li Z, Li P, 2024 Prevalent aberrant condensates of onco-fusion transcription factors and their dissolution as potential cancer therapy, Wang Y, Yu C, Pei G, Jia W, Li T, Li P, 2023 Programming cell-surface signaling by phase-separation-controlled compartmentalization, Li R, Li T, Lu G, Cao Z, Chen B, Wang Y, Du J, Li P, 2022 Histone H2B.8 compacts flowering plant sperm through chromatin phase separation, Buttress T, He S, Wang L, Zhou S, Saalbach G, Vickers M, Li G, Li P, Feng X, 2022 Screening membraneless organelle participants with machine-learning models that integrate multimodal features, Chen Z, Hou C, Wang L, Yu C, Chen T, Shen B, Hou Y, Li P, Li T, 2022 Myosin 1D and the branched actin network control the condensation of p62 bodies, Feng X, Du W, Ding M, Zhao W, Xirefu X, Ma M, Zhuang Y, Fu X, Shen J, Zhang J, Lei X, Sun D, Xi Q, Aisa Y, Chen Q, Li Y, Wang W, Huang S, Yu L, Li P, Mi N, 2022 Compartmentalization-aided interaction screening reveals extensive high-order complexes within the SARS-CoV-2 proteome, Xu W, Pei G, Liu H, Ju X, Wang J, Ding Q, Li P, 2021 Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes, Fang X, Wang L, Ishikawa R, Li Y, Fiedler M, Liu F, Calder G, Rowan B, Weigel D, Li P, Dean C, 2019 Phase transitions in the assembly of multivalent signalling proteins, Li P, Banjade S, Cheng HC, Kim S, Chen B, Guo L, Llaguno M, Hollingsworth JV, King DS, Banani SF, Russo PS, Jiang QX, Nixon BT, Rosen MK, 2012

Areas of Focus

Universal regulatory mechanisms and laws of phase separation phenomena
Biological significance of phase separation in autophagy, transcriptional regulation, and epigenetics
Technology development and applications based on phase separation

Publications

Dual-Role Transcription Factors Stabilize Intermediate Expression Levels, He J, Huo X, Pei G, Jia Z, Yan Y, Yu J, Qu H, Xie Y, Yuan J, Zheng Y, Hu Y, Shi M, You K, Li T, Ma T, Zhang M Q, Ding S, Li P*, Li Y*, 2024
An all-in-one targeted protein degradation platform guided by degradation condensates-bridging bi-specific nanobodies, Jia W, Li W, Li Z*, Li P*, 2024
Prevalent aberrant condensates of onco-fusion transcription factors and their dissolution as potential cancer therapy, Wang Y, Yu C, Pei G, Jia W, Li T*, Li P*, 2023
Programming cell-surface signaling by phase-separation-controlled compartmentalization, Li R, Li T, Lu G, Cao Z, Chen B, Wang Y, Du J*, Li P*, 2022
Histone H2B.8 compacts flowering plant sperm through chromatin phase separation, Buttress T, He S, Wang L, Zhou S, Saalbach G, Vickers M, Li G, Li P*, Feng X*, 2022
Screening membraneless organelle participants with machine-learning models that integrate multimodal features, Chen Z, Hou C, Wang L, Yu C, Chen T, Shen B, Hou Y, Li P*, Li T*, 2022
Myosin 1D and the branched actin network control the condensation of p62 bodies, Feng X, Du W, Ding M, Zhao W, Xirefu X, Ma M, Zhuang Y, Fu X, Shen J, Zhang J, Lei X, Sun D, Xi Q, Aisa Y, Chen Q, Li Y, Wang W, Huang S, Yu L, Li P*, Mi N*, 2022
Compartmentalization-aided interaction screening reveals extensive high-order complexes within the SARS-CoV-2 proteome, Xu W, Pei G, Liu H, Ju X, Wang J, Ding Q, Li P*, 2021
Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes, Fang X, Wang L, Ishikawa R, Li Y, Fiedler M, Liu F, Calder G, Rowan B, Weigel D, Li P*, Dean C*, 2019
Phase transitions in the assembly of multivalent signalling proteins, Li P, Banjade S, Cheng HC, Kim S, Chen B, Guo L, Llaguno M, Hollingsworth JV, King DS, Banani SF, Russo PS, Jiang QX, Nixon BT, Rosen MK*, 2012

Phase Separation Regulatory Mechanisms Universal Laws Autophagy Transcriptional Regulation Epigenetics Technology Development Biological Significance Applications Biomolecular

Ping Chen - Tongji University

Chenguang Liu - Shanghai Jiao Tong University

Li Pilong - Tsinghua University

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