Xueming Li

Chinese, English

Beijing

Tsinghua University

Life Sciences

• 1998-2002 Bachelor: Beijing University of Science and Technology, Department of Material Physics
• 2002-2005 Master: Beijing University of Science and Technology, Department of Material Physics and Chemistry
• 2005-2009 PhD: Institute of Physics, Chinese Academy of Sciences, Condensed Matter Physics

• 2009-2013 - University of California, San Francisco - Postdoctoral Researcher
• 2014-present - Tsinghua University, School of Life Sciences - Assistant Professor, Associate Professor
• 2014-present - Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology - Researcher

Theoretical and methodological research in cryo-electron microscopy
Development and application of cutting-edge electron microscopy technology for ultra-high resolution 3D reconstruction of biological structures
Application of electron microscopy in structural biology to address significant biological questions
Development of advanced experimental and image processing analysis techniques, and artificial intelligence technologies for understanding life activities at atomic or molecular levels
Promotion of cryo-electron microscopy technology in drug design and medical fields

• Locating cellular contents during cryoFIB milling using cellular secondary-electron imaging, Xueming Li et al., 2023
• CryoFIB milling large tissue samples for cryo-electron tomography, Xueming Li et al., 2023
• EPicker is an exemplar-based continual learning approach for knowledge accumulation in cryoEM particle picking, Xueming Li et al., 2022
• Structure deformation and curvature sensing of PIEZO1 in lipid membranes, Xueming Li et al., 2022
• Unit quaternion description of spatial rotations in 3D electron cryo-microscopy, Xueming Li et al., 2020
• Assembly and Substrate Recognition of Curli Biogenesis System, Xueming Li et al., 2020
• Programming conventional electron microscopes for solving ultrahigh-resolution structures of small and macro-molecules, Xueming Li et al., 2019
• Mechanism of DNA translocation underlying chromatin remodeling by Snf2, Xueming Li et al., 2019
• Using Focus Ion Beam to Prepare Crystal Lamella for Electron Diffraction, Xueming Li et al., 2019
• A particle-filter framework for robust cryoEM 3D reconstruction, Xueming Li et al., 2018