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Yi Lin
linyi@mail.tsinghua.edu.cn
Chinese, English
Beijing
Tsinghua University
Life Sciences
  • 2005-2009 Bachelor: Jiangnan University
  • 2009-2014 PhD: Marquette University
  • 2014-2020 Postdoctoral Researcher: University of Texas Southwestern Medical Center
  • 2020-2023 Assistant Professor, Tsinghua University School of Life Sciences
  • 2024-present Associate Professor, Tsinghua University School of Life Sciences
  • 2020-present Researcher, Tsinghua-IDG/McGovern Institute for Brain Science, Tsinghua-Peking University Center for Life Sciences
  • Oliver Smith Academic Achievement Award (2013)
  • Marquette University Fellowship (2012-2014)
  • Richard W. Jobling Award (2012-2013)
Phase separation in biomolecules and neurodegenerative disease research
  • Phase separation as a possible mechanism for dosage sensitivity, Liang Yang, Jiali Lyu, Xi Li, Gaigai Guo, Xueya Zhou, Taoyu Chen, Yi Lin, Tingting Li, 2024
  • Condensation matters, Ke Ruan, Yi Lin, Peiguo Yang, Wen Zhou, 2023
  • Abnormal phase separation of biomacromolecules in human diseases, Songhao Zhang, Gaofeng Pei, Boya Li, Pilong Li, Yi Lin, 2023
  • Circadian clocks are modulated by compartmentalized oscillating translation, Yanrong Zhuang, Zhiyuan Li, Shiyue Xiong, Chujie Sun, Boya Li, Shuangcheng Alivia Wu, Jiali Lyu, Xiang Shi, Liang Yang, Yutong Chen, Zhangbin Bao, Xi Li, Chuhanwen Sun, Yuling Chen, Haiteng Deng, Tingting Li, Qingfeng Wu, Ling Qi, Yue Huang, Xuerui Yang, Yi Lin, 2023
  • The mechanisms to dispose of misfolded proteins in the endoplasmic reticulum of adipocytes, Shuangcheng Alivia Wu, Chenchen Shen, Xiaoqiong Wei, Xiawei Zhang, Siwen Wang, Xinxin Chen, Mauricio Torres, You Lu, Liangguang Leo Lin, Huilun Helen Wang, Allen H Hunter, Deyu Fang, Shengyi Sun, Magdalena I Ivanova, Yi Lin, Ling Qi, 2023
  • Recruitment of TRIM33 to cell-context specific PML nuclear bodies regulates nodal signaling in mESCs, Hongyao Sun, Yutong Chen, Kun Yan, Yanqiu Shao, Qiangfeng C Zhang, Yi Lin, Qiaoran Xi, 2023
  • A brief guideline for studies of phase-separated biomolecular condensates, Yifei Gao, Xi Li, Pilong Li, Yi Lin, 2022
  • Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset, Xiang Shi, Yanrong Zhuang, Zhenhua Chen, Mingrui Xu, Junqi Kuang, Xue-Lian Sun, Lisen Gao, Xia Kuang, Huairen Zhang, Wei Li, Samuel Zheng Hao Wong, Chuanyu Liu, Longqi Liu, Danhua Jiang, Duanqing Pei, Yi Lin, QingFeng Wu, 2022
  • Phase separation in RNA biology, Yi Lin, Xiaofeng Fang, 2021
  • Redox-mediated regulation of an evolutionarily conserved cross-beta structure formed by the TDP43 LC domain, Yi Lin, Xiaoming Zhou, Masato Kato, Daifei Liu, Sina Ghaemmaghami, Benjamin P Tu, Steven L McKnight, 2020
  • Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains, Dylan T Murray, Masato Kato, Yi Lin, Kent R Thurber, Ivan Hung, Steven L McKnight, Robert Tycko, 2017
  • Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers, Yi Lin, Eiichiro Mori, Masato Kato, Siheng Xiang, Leeju Wu, Ilmin Kwon, Steven L McKnight, 2016
Phase Separation Biomolecules Neurodegenerative Diseases Cell Organelles Protein Aggregation Molecular Mechanisms Disease Models Neurobiology Cellular Functions Pathological Changes

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