Professor | Jun Liu | Asia Growth Partners

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Name	Jun Liu
Contact Information	{'en': 'Email: junliu1223 (AT) pku.edu.cn, Office Phone: 62767268, Lab Phone: 62767299', 'zh': '电子邮件：junliu1223 (AT) pku.edu.cn, 办公室电话：62767268, 实验室电话：62767299', 'de': 'E-Mail: junliu1223 (AT) pku.edu.cn, Bürotelefon: 62767268, Labortelefon: 62767299'}
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Jun Liu

Contact Information

{'en': 'Email: junliu1223 (AT) pku.edu.cn, Office Phone: 62767268, Lab Phone: 62767299', 'zh': '电子邮件：junliu1223 (AT) pku.edu.cn, 办公室电话：62767268, 实验室电话：62767299', 'de': 'E-Mail: junliu1223 (AT) pku.edu.cn, Bürotelefon: 62767268, Labortelefon: 62767299'}

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences
Academic Background & Achievements	2010-2015: PhD in Chemical Biology, Peking University 2006-2010: Bachelor of Science in Chemistry, Peking University
Work Experience	2020.9-present: Researcher, Peking University-Tsinghua University Center for Life Sciences 2020.9-present: Researcher, School of Life Sciences, Peking University 2015.11-2020.8: Postdoctoral Fellow, Department of Chemistry, University of Chicago
Awards	Bayer Scholar, 2022 Peking University Boya Young Scholar, 2022 Yifang Scholar, 2021 Beijing Science and Technology Rising Star, 2021

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences

Academic Background & Achievements

2010-2015: PhD in Chemical Biology, Peking University
2006-2010: Bachelor of Science in Chemistry, Peking University

Work Experience

2020.9-present: Researcher, Peking University-Tsinghua University Center for Life Sciences
2020.9-present: Researcher, School of Life Sciences, Peking University
2015.11-2020.8: Postdoctoral Fellow, Department of Chemistry, University of Chicago

Awards

Bayer Scholar, 2022
Peking University Boya Young Scholar, 2022
Yifang Scholar, 2021
Beijing Science and Technology Rising Star, 2021

Areas of Focus	Molecular regulatory mechanisms of RNA epigenetic modifications on chromatin structure and gene transcription Molecular regulatory mechanisms of ncRNA degradation within the cell nucleus Regulatory mechanisms of RNA epigenetic modifications on biomolecular phase transitions
Publications	METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity, Dou, X. Y., Huang, L. L., Xiao, Y., Liu, C., Li, Y. N., Zhang, X. N., Yu, L. S., Zhao, R., Yang, L., Chen, C., Yu, X. B., Gao, B. Y., Qi, M. J., Gao, Y. W., Shen, B., Sun, S. Y., He, C., Liu, J., 2023 N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription, Liu, J., Dou, X. Y., Chen, C. Y., Chen, C., Liu, C., Xu, M. M., Zhao, S. Q., Shen, B., Gao, Y. W., Han, D. L., He, C., 2020 Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer, Wang, M., Liu, J., Zhao, Y., He, R., Xu, X., Guo, X., Li, X., Xu, S., Miao, J., Guo, J., Zhang, H., Gong, J., Zhu, F., Tian, R., Shi, C., Peng, F., Feng, Y., Yu, S., Xie, Y., Jiang, J., Li, M., Wei, W., He, C., Qin, R., 2020 YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma, Hou, J., Zhang, H., Liu, J., Zhao, Z., Wang, J., Lu, Z., Hu, B., Zhou, J., Zhao, Z., Feng, M., Zhang, H., Shen, B., Huang, X., Sun, B., Smyth, M., He, C., Xia, Q., 2019 Anti-tumor immunity controlled through mRNA m6A and YTHDF1 in dendritic cells, Han, D., Liu, J., Chen, C., Dong, L., Huang, X., Liu, Y., Wang, J., Dougherty, U., Bissonnette, B., Shen, B., Weichselbaum, R., Xu, M., He, C., 2019 m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer, Liu, J., Eckert, M., Harada, B., Liu, S., Lu, Z., Yu, K., Tienda, S., Chryplewicz, A., Zhu, A., Yang, Y., Huang, J., Chen, S., Xu, Z., Leng, X., Yu, X., Cao, J., Zhang, Z., Liu, J., Lengyel, E., He, C., 2018 VIRMA mediates preferential m6A mRNA methylation in 3`UTR and near stop codon and associates with alternative polyadenylation, Yue, Y., Liu, J., Cui, X., Cao, J., Luo, G., Zhang, Z., Gao, M., Shu, X., Ma, H., Wang, F., Shen, B., Wang, Y., Feng, X., He, C., Liu, J., 2018

Areas of Focus

Molecular regulatory mechanisms of RNA epigenetic modifications on chromatin structure and gene transcription
Molecular regulatory mechanisms of ncRNA degradation within the cell nucleus
Regulatory mechanisms of RNA epigenetic modifications on biomolecular phase transitions

Publications

METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity, Dou, X. Y., Huang, L. L., Xiao, Y., Liu, C., Li, Y. N., Zhang, X. N., Yu, L. S., Zhao, R., Yang, L., Chen, C., Yu, X. B., Gao, B. Y., Qi, M. J., Gao, Y. W., Shen, B., Sun, S. Y., He, C., Liu, J., 2023
N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription, Liu, J., Dou, X. Y., Chen, C. Y., Chen, C., Liu, C., Xu, M. M., Zhao, S. Q., Shen, B., Gao, Y. W., Han, D. L., He, C., 2020
Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer, Wang, M., Liu, J., Zhao, Y., He, R., Xu, X., Guo, X., Li, X., Xu, S., Miao, J., Guo, J., Zhang, H., Gong, J., Zhu, F., Tian, R., Shi, C., Peng, F., Feng, Y., Yu, S., Xie, Y., Jiang, J., Li, M., Wei, W., He, C., Qin, R., 2020
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma, Hou, J., Zhang, H., Liu, J., Zhao, Z., Wang, J., Lu, Z., Hu, B., Zhou, J., Zhao, Z., Feng, M., Zhang, H., Shen, B., Huang, X., Sun, B., Smyth, M., He, C., Xia, Q., 2019
Anti-tumor immunity controlled through mRNA m6A and YTHDF1 in dendritic cells, Han, D., Liu, J., Chen, C., Dong, L., Huang, X., Liu, Y., Wang, J., Dougherty, U., Bissonnette, B., Shen, B., Weichselbaum, R., Xu, M., He, C., 2019
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer, Liu, J., Eckert, M., Harada, B., Liu, S., Lu, Z., Yu, K., Tienda, S., Chryplewicz, A., Zhu, A., Yang, Y., Huang, J., Chen, S., Xu, Z., Leng, X., Yu, X., Cao, J., Zhang, Z., Liu, J., Lengyel, E., He, C., 2018
VIRMA mediates preferential m6A mRNA methylation in 3`UTR and near stop codon and associates with alternative polyadenylation, Yue, Y., Liu, J., Cui, X., Cao, J., Luo, G., Zhang, Z., Gao, M., Shu, X., Ma, H., Wang, F., Shen, B., Wang, Y., Feng, X., He, C., Liu, J., 2018

Rna Epigenetics Chromatin Gene Transcription Ncrna Degradation Cell Nucleus Biomolecular Phase Transition Regulatory Mechanisms

Li Pilong - Tsinghua University

Li Pilong - Tsinghua University

Zhang He - Tongji University

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