Professor | Xiangjun Tong | Asia Growth Partners

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Name	Xiangjun Tong
Contact Information	xiangjuntong@pku.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Xiangjun Tong

Contact Information

xiangjuntong@pku.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences
Academic Background & Achievements	1999 - 2002: Postdoctoral, UCLA School of Medicine, USA 1998 - 1999: Postdoctoral, University of Tokyo Medical School, Japan 1995 - 1998: PhD in Cell Biology, Peking University School of Life Sciences 1992 - 1995: Master of Science in Cell Biology, Peking University School of Life Sciences 1988 - 1992: Bachelor of Science in Cell Biology, Peking University Department of Biology
Work Experience	Since August 2017: Professor and PhD Supervisor, Peking University School of Life Sciences 2002 - 2017: Associate Professor, Peking University School of Life Sciences 1998 - 2002: Lecturer, Peking University School of Life Sciences
Awards	Peking University Teaching Excellence Award, 2016 Peking University Teaching Excellence Award, 2012 Peking University Teaching Demonstration Competition First Prize, 2012 Peking University Teaching Excellence Award, 2010 Capital Education Pioneer - Teaching Innovation Advanced Individual, 2009 Ministry of Education 'New Century Excellent Talents Support Plan' Awardee, 2008 10th Huo Yingdong Young Teacher Award (Research Third Prize), 2006 Peking University 'Dongbao' Teaching Award, 2005 Peking University Teaching Excellence Award, 2003

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences

Academic Background & Achievements

1999 - 2002: Postdoctoral, UCLA School of Medicine, USA
1998 - 1999: Postdoctoral, University of Tokyo Medical School, Japan
1995 - 1998: PhD in Cell Biology, Peking University School of Life Sciences
1992 - 1995: Master of Science in Cell Biology, Peking University School of Life Sciences
1988 - 1992: Bachelor of Science in Cell Biology, Peking University Department of Biology

Work Experience

Since August 2017: Professor and PhD Supervisor, Peking University School of Life Sciences
2002 - 2017: Associate Professor, Peking University School of Life Sciences
1998 - 2002: Lecturer, Peking University School of Life Sciences

Awards

Peking University Teaching Excellence Award, 2016
Peking University Teaching Excellence Award, 2012
Peking University Teaching Demonstration Competition First Prize, 2012
Peking University Teaching Excellence Award, 2010
Capital Education Pioneer - Teaching Innovation Advanced Individual, 2009
Ministry of Education 'New Century Excellent Talents Support Plan' Awardee, 2008
10th Huo Yingdong Young Teacher Award (Research Third Prize), 2006
Peking University 'Dongbao' Teaching Award, 2005
Peking University Teaching Excellence Award, 2003

Areas of Focus	Formation of internal organs in zebrafish, especially the development of the cardiovascular system Research on the pathogenesis of congenital heart diseases in humans based on zebrafish models Development and refinement of CRISPR/Cas-based genome editing techniques using zebrafish (Danio rerio) as a model organism
Publications	Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish, Tong X, Zu Y, Li Z, Li W, Ying L, Yang J, Wang X, He S, Liu D, Zhu Z, Chen J, Lin S, Zhang B, 2014 Eif3ba regulates cranial neural crest development by modulating p53 in zebrafish, Xia Z, Tong X, Liang F, Zhang Y, Kuok C, Zhang Y, Liu X, Zhu Z, Lin S, Zhang B, 2013 Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish, Xiao A, Wang Z, Hu Y, Wu Y, Luo Z, Yang Z, Zu Y, Li W, Huang P, Tong X, Zhu Z, Lin S, Zhang B, 2013 TALEN mediated precise genome modification by homologous recombination in zebrafish, Zu Y, Tong X, Wang Z, Liu D, Pan R, Li Z, Hu Y, Luo Z, Huang P, Wu Q, Zhu Z, Zhang B, Lin S, 2013 ngs (Notochord Granular Surface) Gene Encodes a Novel Type of Intermediate Filament Family Protein Essential for Notochord Maintenance in Zebrafish, Tong X, Xia Z, Zu Y, Telfer H, Hu J, Yu J, Liu H, Zhang Q, Sodmergen, Lin S, Zhang B, 2013 EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration, Ji XD, Li G, Feng YX, Zhao JS, Li JJ, Sun ZJ, Shi S, Deng YZ, Xu JF, Zhu YQ, Koeffler HP, Tong XJ, Xie D, 2011 Involvement of Cyr61 in growth, migration and metastasis of prostate cancer cells, Sun ZJ, Wang Y, Cai Z, Chen PP, Tong XJ, Xie D, 2008 Negative feedback regulation of IFN-gamma pathway by IFN regulatory factor 2 in esophageal cancers, Wang Y, Liu D, Chen P, Koeffler HP, Tong X, Xie D, 2008 Involvements of IFN Regulatory Factor-1 and IFN Regulatory Factor-2 in the Formation and Progression of Human Esophageal Cancers, Wang Y, Liu D, Chen PP, Koeffler HP, Tong X, and Xie D, 2007 Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through beta-catenin-T-cell factor/Lef signaling, Deng YZ, Chen PP, Wang Y, Yin D, Koeffler HP, Li B, Tong XJ, Xie D, 2007 Analyses for binding of the transferrin family of proteins to the transferrin receptor 2, Kawabata H, Tong X, Kawanami T, Wano Y, Hirose Y, Sugai S, Koeffler HP, 2004 RWJ-241947 (MCC-555), a unique peroxisome proliferator-activated receptor-gamma ligand with antitumor activity against human prostate cancer in vitro and in beige/nude/ X-linked immunodeficient mice and enhancement of apoptosis in myeloma cells induced by, Kumagai T, Ikezoe T, Gui D, O`Kelly J, Tong XJ, Cohen FJ, Said JW, Koeffler HP, 2004 Cyr61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway, Tong X, O`Kelly J, Xie D, Mori A, Lemp N, McKenna R, Miller CW, Koeffler HP, 2004 Cyr61 is overexpressed in gliomas and involved in integrin-linked kinase-mediated Akt and beta-catenin-TCF/Lef signaling pathways, Xie D, Yin D, Tong X, O`Kelly J, Mori A, Miller C, Black K, Gui D, Said JW, Koeffler HP, 2004 NADE (p75NTR-associated cell death executor) suppresses cellular growth in vivo, Tong X, Xie D, Roth W, Reed J, Koeffler HP, 2003 Mutation analysis of transferrin-receptor 2 in patients with atypical hemochromatosis, Hoffman WK, Tong XJ, Ajioka RS, Kushner JP, Koeffler HP, 2002 Iron deficiency can upregulate expression of transferrin receptor at both the mRNA and protein level, Tong X, Kawabata H, Koeffler HP, 2002 Cyr61, a member of CCN family, is a tumor suppressor in non-small cell lung cancer, Tong X, Xie D, O`Kelly J, Miller CW, Muller-Tidow C, Koeffler HP, 2001 Regulation of expression of murine transferrin receptor 2, Kawabata H, Germain RS, Ikezoe T, Tong X, Green EM, Gombart AF, Koeffler HP, 2001

Areas of Focus

Formation of internal organs in zebrafish, especially the development of the cardiovascular system
Research on the pathogenesis of congenital heart diseases in humans based on zebrafish models
Development and refinement of CRISPR/Cas-based genome editing techniques using zebrafish (Danio rerio) as a model organism

Publications

Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish, Tong X, Zu Y, Li Z, Li W, Ying L, Yang J, Wang X, He S, Liu D, Zhu Z, Chen J, Lin S, Zhang B, 2014
Eif3ba regulates cranial neural crest development by modulating p53 in zebrafish, Xia Z, Tong X, Liang F, Zhang Y, Kuok C, Zhang Y, Liu X, Zhu Z, Lin S, Zhang B, 2013
Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish, Xiao A, Wang Z, Hu Y, Wu Y, Luo Z, Yang Z, Zu Y, Li W, Huang P, Tong X, Zhu Z, Lin S, Zhang B, 2013
TALEN mediated precise genome modification by homologous recombination in zebrafish, Zu Y, Tong X, Wang Z, Liu D, Pan R, Li Z, Hu Y, Luo Z, Huang P, Wu Q, Zhu Z, Zhang B, Lin S, 2013
ngs (Notochord Granular Surface) Gene Encodes a Novel Type of Intermediate Filament Family Protein Essential for Notochord Maintenance in Zebrafish, Tong X, Xia Z, Zu Y, Telfer H, Hu J, Yu J, Liu H, Zhang Q, Sodmergen, Lin S, Zhang B, 2013
EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration, Ji XD, Li G, Feng YX, Zhao JS, Li JJ, Sun ZJ, Shi S, Deng YZ, Xu JF, Zhu YQ, Koeffler HP, Tong XJ, Xie D, 2011
Involvement of Cyr61 in growth, migration and metastasis of prostate cancer cells, Sun ZJ, Wang Y, Cai Z, Chen PP, Tong XJ, Xie D, 2008
Negative feedback regulation of IFN-gamma pathway by IFN regulatory factor 2 in esophageal cancers, Wang Y, Liu D, Chen P, Koeffler HP, Tong X, Xie D, 2008
Involvements of IFN Regulatory Factor-1 and IFN Regulatory Factor-2 in the Formation and Progression of Human Esophageal Cancers, Wang Y, Liu D, Chen PP, Koeffler HP, Tong X, and Xie D, 2007
Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through beta-catenin-T-cell factor/Lef signaling, Deng YZ, Chen PP, Wang Y, Yin D, Koeffler HP, Li B, Tong XJ, Xie D, 2007
Analyses for binding of the transferrin family of proteins to the transferrin receptor 2, Kawabata H, Tong X, Kawanami T, Wano Y, Hirose Y, Sugai S, Koeffler HP, 2004
RWJ-241947 (MCC-555), a unique peroxisome proliferator-activated receptor-gamma ligand with antitumor activity against human prostate cancer in vitro and in beige/nude/ X-linked immunodeficient mice and enhancement of apoptosis in myeloma cells induced by, Kumagai T, Ikezoe T, Gui D, O`Kelly J, Tong XJ, Cohen FJ, Said JW, Koeffler HP, 2004
Cyr61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway, Tong X, O`Kelly J, Xie D, Mori A, Lemp N, McKenna R, Miller CW, Koeffler HP, 2004
Cyr61 is overexpressed in gliomas and involved in integrin-linked kinase-mediated Akt and beta-catenin-TCF/Lef signaling pathways, Xie D, Yin D, Tong X, O`Kelly J, Mori A, Miller C, Black K, Gui D, Said JW, Koeffler HP, 2004
NADE (p75NTR-associated cell death executor) suppresses cellular growth in vivo, Tong X, Xie D, Roth W, Reed J, Koeffler HP, 2003
Mutation analysis of transferrin-receptor 2 in patients with atypical hemochromatosis, Hoffman WK, Tong XJ, Ajioka RS, Kushner JP, Koeffler HP, 2002
Iron deficiency can upregulate expression of transferrin receptor at both the mRNA and protein level, Tong X, Kawabata H, Koeffler HP, 2002
Cyr61, a member of CCN family, is a tumor suppressor in non-small cell lung cancer, Tong X, Xie D, O`Kelly J, Miller CW, Muller-Tidow C, Koeffler HP, 2001
Regulation of expression of murine transferrin receptor 2, Kawabata H, Germain RS, Ikezoe T, Tong X, Green EM, Gombart AF, Koeffler HP, 2001

Zebrafish Internal Organs Cardiovascular Development Congenital Heart Disease Pathogenesis Crispr/Cas Genome Editing Model Organism Gene Function Gene Regulation

Xueyan Yang - Fudan University

Bo Zhang - Peking University

Ren X - Huazhong University of Science and Technology

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