Professor | Yan Zhang | Asia Growth Partners

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Name	Yan Zhang
Contact Information	{'en': 'Email: yanzhang (AT) pku.edu.cn, Office Phone: 62754880, Lab Phone: 62754880', 'zh': '电子邮件：yanzhang (AT) pku.edu.cn, 办公室电话：62754880, 实验室电话：62754880', 'de': 'E-Mail: yanzhang (AT) pku.edu.cn, Bürotelefon: 62754880, Labortelefon: 62754880'}
Language ability	English, Chinese
Province	Beijing

Upload Avatar (500 x 500)

Name

Yan Zhang

Contact Information

{'en': 'Email: yanzhang (AT) pku.edu.cn, Office Phone: 62754880, Lab Phone: 62754880', 'zh': '电子邮件：yanzhang (AT) pku.edu.cn, 办公室电话：62754880, 实验室电话：62754880', 'de': 'E-Mail: yanzhang (AT) pku.edu.cn, Bürotelefon: 62754880, Labortelefon: 62754880'}

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences
Academic Background & Achievements	1999 - 2003, PhD in Neurology and Neurosurgery, McGill University 1997 - 1999, Master of Science in Psychology, Carleton University 1993 - 1997, Bachelor of Science in Psychology, Peking University
Work Experience	2012 - Present, Professor, School of Life Sciences, Peking University 2005 - 2012, Associate Professor, School of Life Sciences, Peking University
Awards	2018: China Young Women Scientist Award 2014: National Science Fund for Distinguished Young Scholars

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences

Academic Background & Achievements

1999 - 2003, PhD in Neurology and Neurosurgery, McGill University
1997 - 1999, Master of Science in Psychology, Carleton University
1993 - 1997, Bachelor of Science in Psychology, Peking University

Work Experience

2012 - Present, Professor, School of Life Sciences, Peking University
2005 - 2012, Associate Professor, School of Life Sciences, Peking University

Awards

2018: China Young Women Scientist Award
2014: National Science Fund for Distinguished Young Scholars

Areas of Focus	Mechanisms of cell death in neurodegenerative diseases Amyloid toxicity and metabolism in Alzheimer's disease, neuronal polarity, and biomarkers Mechanisms of axonal degeneration in Alzheimer's disease
Publications	High-performance plasma biomarkers panel for Alzheimer’s disease screening through an femto level label-free biosensing system, Wang S, Deng R, Chen Z-Y, Huang L, Song Y, Yuan D, Li Y, Liu H, Yang F, Fan B, Xu Y, Zhao Z, Li Y, Zhang Y, 2023 5-HT6R mull mutation induces synaptic and cognitive defects, Sun Z, Wang B, Chen C, Li C, Zhang Y, 2021 Structural basis for Draxin-modulated axon guidance and fasciculation by Netrin-1 through DCC, Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang J-H, Meijers R, 2018 Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer’s disease by regulating cilia function, Hu L, Wang B, Zhang Y, 2017 Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC, Finci L, Zhang J, Sun X, Smock RG, Meijers R, Xiao J, Zhang Y, Wang J-H, 2017 Selective filtering defect at the axon initial segment in Alzheimer, Sun X, Wu Y, Gu M, Liu Z, Ma Y, Li J, Zhang Y, 2014 The crystal structure of netrin-1 in complex with DCC reveals the bi-functionality of netrin-1 as a guidance cue, Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HDT, Svergun DI, Zhang Y, Wang J-H, Meijers R, 2014 MiR-342-5p Decreases Ankyrin G Level in Alzheimer’s Disease Transgenic Mouse Models, Sun X, Wu Y, Gu M, Zhang Y, 2014 Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70, Cui J, Wang Y, Dong Q, Wu S, Xiao X, Hu J, Chai Z, Zhang Y, 2011 Tunneling-nanotube development in astrocytes depends on p53 activation, Wang Y, Cui J, Sun X, Zhang Y, 2011

Areas of Focus

Mechanisms of cell death in neurodegenerative diseases
Amyloid toxicity and metabolism in Alzheimer's disease, neuronal polarity, and biomarkers
Mechanisms of axonal degeneration in Alzheimer's disease

Publications

High-performance plasma biomarkers panel for Alzheimer’s disease screening through an femto level label-free biosensing system, Wang S, Deng R, Chen Z-Y, Huang L, Song Y, Yuan D, Li Y, Liu H, Yang F, Fan B, Xu Y, Zhao Z, Li Y, Zhang Y, 2023
5-HT6R mull mutation induces synaptic and cognitive defects, Sun Z, Wang B, Chen C, Li C, Zhang Y, 2021
Structural basis for Draxin-modulated axon guidance and fasciculation by Netrin-1 through DCC, Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang J-H, Meijers R, 2018
Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer’s disease by regulating cilia function, Hu L, Wang B, Zhang Y, 2017
Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC, Finci L, Zhang J, Sun X, Smock RG, Meijers R, Xiao J, Zhang Y, Wang J-H, 2017
Selective filtering defect at the axon initial segment in Alzheimer, Sun X, Wu Y, Gu M, Liu Z, Ma Y, Li J, Zhang Y, 2014
The crystal structure of netrin-1 in complex with DCC reveals the bi-functionality of netrin-1 as a guidance cue, Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HDT, Svergun DI, Zhang Y, Wang J-H, Meijers R, 2014
MiR-342-5p Decreases Ankyrin G Level in Alzheimer’s Disease Transgenic Mouse Models, Sun X, Wu Y, Gu M, Zhang Y, 2014
Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70, Cui J, Wang Y, Dong Q, Wu S, Xiao X, Hu J, Chai Z, Zhang Y, 2011
Tunneling-nanotube development in astrocytes depends on p53 activation, Wang Y, Cui J, Sun X, Zhang Y, 2011

Cell Death Neurodegeneration Alzheimer'S Disease Amyloid Neuronal Polarity Biomarkers Axonal Degeneration Toxicity Metabolism Mechanisms

Ping Yong - Shanghai Jiao Tong University

Haiming Luo - Huazhong University of Science and Technology

Yu Chen - University of Chinese Academy of Sciences

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