Professor | 张研 | 数字化转型顾问

	Upload Avatar (500 x 500)
Name	张研
Contact Information	{'en': 'Email: yanzhang (AT) pku.edu.cn, Office Phone: 62754880, Lab Phone: 62754880', 'zh': '电子邮件：yanzhang (AT) pku.edu.cn, 办公室电话：62754880, 实验室电话：62754880', 'de': 'E-Mail: yanzhang (AT) pku.edu.cn, Bürotelefon: 62754880, Labortelefon: 62754880'}
Language ability	英语, 汉语
Province	北京

Upload Avatar (500 x 500)

Name

张研

Contact Information

{'en': 'Email: yanzhang (AT) pku.edu.cn, Office Phone: 62754880, Lab Phone: 62754880', 'zh': '电子邮件：yanzhang (AT) pku.edu.cn, 办公室电话：62754880, 实验室电话：62754880', 'de': 'E-Mail: yanzhang (AT) pku.edu.cn, Bürotelefon: 62754880, Labortelefon: 62754880'}

Language ability

英语, 汉语

Province

北京

University/Lab Affiliation and Title	北京大学
Faculty	Life Sciences
Academic Background & Achievements	1999 - 2003, 理学博士, 神经内科及神经外科学系, 麦吉尔大学 1997 - 1999, 理学硕士, 心理学系, 卡尔顿大学 1993 - 1997, 理学学士, 心理学系, 北京大学
Work Experience	2012 - 至今, 教授, 北京大学生命科学学院 2005 - 2012, 副教授, 北京大学生命科学学院
Awards	2018: 中国青年女科学家奖 2014: 国家杰出青年基金

University/Lab Affiliation and Title

北京大学

Faculty

Life Sciences

Academic Background & Achievements

1999 - 2003, 理学博士, 神经内科及神经外科学系, 麦吉尔大学
1997 - 1999, 理学硕士, 心理学系, 卡尔顿大学
1993 - 1997, 理学学士, 心理学系, 北京大学

Work Experience

2012 - 至今, 教授, 北京大学生命科学学院
2005 - 2012, 副教授, 北京大学生命科学学院

Awards

2018: 中国青年女科学家奖
2014: 国家杰出青年基金

Areas of Focus	神经退行性疾病中的细胞死亡机制研究阿尔茨海默病中的淀粉样蛋白毒性和代谢，神经元极性和生物标记物研究阿尔茨海默病中轴突退行性病变的机制
Publications	High-performance plasma biomarkers panel for Alzheimer’s disease screening through an femto level label-free biosensing system, Wang S, Deng R, Chen Z-Y, Huang L, Song Y, Yuan D, Li Y, Liu H, Yang F, Fan B, Xu Y, Zhao Z, Li Y, Zhang Y, 2023 5-HT6R mull mutation induces synaptic and cognitive defects, Sun Z, Wang B, Chen C, Li C, Zhang Y, 2021 Structural basis for Draxin-modulated axon guidance and fasciculation by Netrin-1 through DCC, Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang J-H, Meijers R, 2018 Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer’s disease by regulating cilia function, Hu L, Wang B, Zhang Y, 2017 Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC, Finci L, Zhang J, Sun X, Smock RG, Meijers R, Xiao J, Zhang Y, Wang J-H, 2017 Selective filtering defect at the axon initial segment in Alzheimer, Sun X, Wu Y, Gu M, Liu Z, Ma Y, Li J, Zhang Y, 2014 The crystal structure of netrin-1 in complex with DCC reveals the bi-functionality of netrin-1 as a guidance cue, Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HDT, Svergun DI, Zhang Y, Wang J-H, Meijers R, 2014 MiR-342-5p Decreases Ankyrin G Level in Alzheimer’s Disease Transgenic Mouse Models, Sun X, Wu Y, Gu M, Zhang Y, 2014 Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70, Cui J, Wang Y, Dong Q, Wu S, Xiao X, Hu J, Chai Z, Zhang Y, 2011 Tunneling-nanotube development in astrocytes depends on p53 activation, Wang Y, Cui J, Sun X, Zhang Y, 2011

Areas of Focus

神经退行性疾病中的细胞死亡机制研究
阿尔茨海默病中的淀粉样蛋白毒性和代谢，神经元极性和生物标记物研究
阿尔茨海默病中轴突退行性病变的机制

Publications

High-performance plasma biomarkers panel for Alzheimer’s disease screening through an femto level label-free biosensing system, Wang S, Deng R, Chen Z-Y, Huang L, Song Y, Yuan D, Li Y, Liu H, Yang F, Fan B, Xu Y, Zhao Z, Li Y, Zhang Y, 2023
5-HT6R mull mutation induces synaptic and cognitive defects, Sun Z, Wang B, Chen C, Li C, Zhang Y, 2021
Structural basis for Draxin-modulated axon guidance and fasciculation by Netrin-1 through DCC, Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang J-H, Meijers R, 2018
Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer’s disease by regulating cilia function, Hu L, Wang B, Zhang Y, 2017
Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC, Finci L, Zhang J, Sun X, Smock RG, Meijers R, Xiao J, Zhang Y, Wang J-H, 2017
Selective filtering defect at the axon initial segment in Alzheimer, Sun X, Wu Y, Gu M, Liu Z, Ma Y, Li J, Zhang Y, 2014
The crystal structure of netrin-1 in complex with DCC reveals the bi-functionality of netrin-1 as a guidance cue, Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HDT, Svergun DI, Zhang Y, Wang J-H, Meijers R, 2014
MiR-342-5p Decreases Ankyrin G Level in Alzheimer’s Disease Transgenic Mouse Models, Sun X, Wu Y, Gu M, Zhang Y, 2014
Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70, Cui J, Wang Y, Dong Q, Wu S, Xiao X, Hu J, Chai Z, Zhang Y, 2011
Tunneling-nanotube development in astrocytes depends on p53 activation, Wang Y, Cui J, Sun X, Zhang Y, 2011

细胞死亡神经退行性阿尔茨海默病淀粉样蛋白神经元极性生物标记物轴突退行性毒性代谢机制

王晓丹 - 华东师范大学

Area of Focus
营养 | 代谢 | 调控 | 水生 | 动物 | 经济 | 生理 | 机制 | 分子 | 进化 | 逆境 | 生理学 | 适应 | 不利 | 条件 | 遗传

俞芳 - 上海师范大学

Area of Focus
叶绿体 | 发育 | 代谢 | 分子 | 机制 | 遗传学 | 生物化学 | 结构生物学 | 植物科学 | 细胞生物学

陈雪梅 - 北京大学

Area of Focus
花 | 发育 | 基因 | 调控 | 蛋白 | 器官 | 分化 | 小Rna | 代谢 | 功能 | 生物合成 | 降解 | 机制 | 细胞 | 运输 | 信号 | 温度 | 响应 | 修饰 | Rna | 叶绿体 | 表达 | Nad | Fad | Dpcoa | 加帽

View All

Personal Information

Academic Information

Research

联系我们

还未创建账户?

Personal Information

Academic Information

Research

联系我们