Professor | Shan Bian | Asia Growth Partners

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Name	Shan Bian
Contact Information	shan_bian@tongji.edu.cn
Language ability	Chinese, English, German
Province	Shanghai

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Name

Shan Bian

Contact Information

shan_bian@tongji.edu.cn

Language ability

Chinese, English, German

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2004 - Bachelor and Master's degrees from China Pharmaceutical University 2009 - PhD from University of Freiburg, Germany, under Melitta Schachner Published as first and corresponding author in journals like Nature Methods, Cell Research
Work Experience	2010-2013 - Postdoctoral Research at Weill Medical College of Cornell University, USA 2014-2018 - Postdoctoral Research at Institute of Molecular Biotechnology, Austrian Academy of Sciences 2019-present - Distinguished Researcher at Tongji University, School of Life Sciences and Technology

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2004 - Bachelor and Master's degrees from China Pharmaceutical University
2009 - PhD from University of Freiburg, Germany, under Melitta Schachner
Published as first and corresponding author in journals like Nature Methods, Cell Research

Work Experience

2010-2013 - Postdoctoral Research at Weill Medical College of Cornell University, USA
2014-2018 - Postdoctoral Research at Institute of Molecular Biotechnology, Austrian Academy of Sciences
2019-present - Distinguished Researcher at Tongji University, School of Life Sciences and Technology

Areas of Focus	Development of human nervous system using brain and optic nerve organoids Mechanisms and treatments of neurological diseases using organoids Brain and optic nerve tumor research using organoids
Publications	RGCC balances self-renewal and neuronal differentiation of neural stem cells in the developing mammalian neocortex, Guo Z, Chen M, Chao Y, Cai C, Liu L, Zhao L, Li L, Bai QR, Xu Y, Niu W, Shi L, Bi Y, Ren D, Yuan F, Shi S, Zeng Q, Han K, Shi Y, Bian S, He G, 2021 Maternal sevoflurane exposure induces temporary defects in interkinetic nuclear migration of radial glial progenitors in the fetal cerebral cortex through the Notch signalling pathway, Jiang M, Tang T, Liang X, Li J, Qiu Y, Liu S, Bian S, Xie Y, Fang F, Cang J, 2021 PAUPAR and PAX6 sequentially regulate human embryonic stem cell cortical differentiation, Xu Y, Xi J, Wang G, Guo Z, Sun Q, Lu C, Ma L, Wu Y, Jia W, Zhu S, Guo X, Bian S, Kang J, 2021 Application of fused organoid models to study human brain development and neural disorders, Chen A, Guo Z, Fang L, Bian S, 2020 Genetically engineered cerebral organoids model formation of brain tumors, Bian S, Repic M, Guo Z, Kavirayani A, Burkard T, Bagley J, Krauditsch C, Knoblich JA, 2018 Opposite Roles of Wnt7a and Sfrp1 in Modulating Proper Development of Neural Progenitors in the Mouse Cerebral Cortex, Miao N, Bian S, Lee T, Mubarak T, Huang S, Wen Z, Hussain G, Sun T, 2018 Fused cerebral organoids model interactions between brain regions, Bagley JA, Reumann D, Bian S, Lévi-Strauss J, Knoblich JA, 2017 Self-organized developmental patterning and differentiation in cerebral organoids, Renner M, Lancaster MA, Bian S, Choi H, Ku T, Peer A, Chung K, Knoblich JA, 2017

Areas of Focus

Development of human nervous system using brain and optic nerve organoids
Mechanisms and treatments of neurological diseases using organoids
Brain and optic nerve tumor research using organoids

Publications

RGCC balances self-renewal and neuronal differentiation of neural stem cells in the developing mammalian neocortex, Guo Z, Chen M, Chao Y, Cai C, Liu L, Zhao L, Li L, Bai QR, Xu Y, Niu W, Shi L, Bi Y, Ren D, Yuan F, Shi S, Zeng Q, Han K, Shi Y, Bian S, He G, 2021
Maternal sevoflurane exposure induces temporary defects in interkinetic nuclear migration of radial glial progenitors in the fetal cerebral cortex through the Notch signalling pathway, Jiang M, Tang T, Liang X, Li J, Qiu Y, Liu S, Bian S, Xie Y, Fang F, Cang J, 2021
PAUPAR and PAX6 sequentially regulate human embryonic stem cell cortical differentiation, Xu Y, Xi J, Wang G, Guo Z, Sun Q, Lu C, Ma L, Wu Y, Jia W, Zhu S, Guo X, Bian S, Kang J, 2021
Application of fused organoid models to study human brain development and neural disorders, Chen A, Guo Z, Fang L, Bian S, 2020
Genetically engineered cerebral organoids model formation of brain tumors, Bian S, Repic M, Guo Z, Kavirayani A, Burkard T, Bagley J, Krauditsch C, Knoblich JA, 2018
Opposite Roles of Wnt7a and Sfrp1 in Modulating Proper Development of Neural Progenitors in the Mouse Cerebral Cortex, Miao N, Bian S, Lee T, Mubarak T, Huang S, Wen Z, Hussain G, Sun T, 2018
Fused cerebral organoids model interactions between brain regions, Bagley JA, Reumann D, Bian S, Lévi-Strauss J, Knoblich JA, 2017
Self-organized developmental patterning and differentiation in cerebral organoids, Renner M, Lancaster MA, Bian S, Choi H, Ku T, Peer A, Chung K, Knoblich JA, 2017

Organoids Neurodevelopment Neurological Diseases Treatment Brain Tumors Optic Nerve Tumors Gene Editing Single-Cell Genomics Neural Stem Cells Cerebral Cortex

Shan Bian - Tongji University

Jie Li - Central South University

Ling Yuan - Central South University

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