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Shi Jiejun
Life Science
Tongji University
Shanghai
Language: Chinese, English
Epigenetics
Polymorphism
Gene Expression
Development
Aging
Tumor Heterogeneity
Diagnosis
Treatment
Multi-Omics
Disease Features
Areas of Focus
- Epigenetic polymorphism in gene expression regulation
- Dynamics of epigenetic polymorphism in early development and aging
- Tumor epigenetic heterogeneity in early diagnosis and treatment
- Multi-omics deep mining to reveal disease molecular features
Work Experience
- 2019-2021 Postdoctoral Fellow/Assistant Researcher at UC Irvine
- 2016-2019 Postdoctoral Fellow at Baylor College of Medicine
- 2013-2014 Visiting Scholar at Memorial Sloan-Kettering Cancer Center
Academic Background & Achievements
- 2007-2011 Bachelor of Biotechnology: Inner Mongolia University
- 2011-2016 PhD in Biology: Tongji University
- 2014 Doctoral National Scholarship
- Published paper on chromatin remodeling in Drosophila (Nucleic acids research, 2014)
Publications
- The Concurrence of DNA Methylation and Demethylation is Associated with Transcription Regulation, Shi J, Xu J, Chen EY, Li SJ, Cui Y, Shen L, Li JJ, and Li W, 2021
- Cellular heterogeneity–adjusted clonal methylation (CHALM) provides better prediction of gene expression, Xu J, Shi J, Cui X, Cui Y, Li JJ, Goel A, Chen X, Su J, Issa J-P, and Li W, 2021
- BAP1 links metabolic regulation of ferroptosis to tumour suppression, Zhang Y, Shi J, Liu X, Feng L, Gong Z, et al., 2018
- H2A monoubiquitination links glucose availability to epigenetic regulation of the endoplasmic reticulum stress response and cancer cell death, Zhang Y, Shi J, Liu X, Xiao Z, et al., 2020
- Drosophila Brahma complex remodels nucleosome organizations in multiple aspects, Shi J, Zheng M, Ye Y, Li M, Chen X, et al., 2014
- Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer, Hsu CC, Shi J, Yuan C, Zhao D, Jiang S, et al., 2018
- Gas41 links histone acetylation to H2A. Z deposition and maintenance of embryonic stem cell identity, Hsu CC, Zhao D, Shi J, Peng D, et al., 2018
- Histone H3. 3 G34 Mutations Alter Histone H3K36 and H3K27 Methylation In Cis, Shi L, Shi J, Shi X, Li W, and Wen H, 2018
- Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes, Xi Y, Shi J, Li W, Tanaka K, Allton KL, et al., 2018
- CORM: An R Package Implementing the Clustering of Regression Models Method for Gene Clustering, Shi J, and Qin L-X, 2014
- Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer, Liu X, Olszewski K, Zhang Y, Lim EW, Shi J, et al., 2020
- Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer, Zheng ZY, Anurag M, Lei JT, …, Shi J, et al., 2020
- S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling, Greco CM, Cervantes M, …, Shi J, et al., 2020
- Defining the independence of the liver circadian clock, Koronowski KB, Kinouchi K, Welz PS, Smith JG, Zinna VM, Shi J, et al., 2019
- The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3, Zhang Y, Xue Y, Shi J, Ahn JW, Mi W, et al., 2018
- Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation, Gates LA, Shi J, Rohira AD, Feng Q, Zhu B, et al., 2017
- The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate, Koppula P, Zhang Y, Shi J, Li W, and Gan B, 2017
- Integration of Feeding Behaviour by the Liver Circadian Clock Reveals Network Dependency of Metabolic Rhythms, Greco CM, Koronowski KB, Smith JG, Shi J, et al., 2021
- NG-Circos: next-generation Circos for data visualization and interpretation, Cui Y, Cui Z, Xu J, Hao D, Shi J, et al., 2020
- Statistical Assessment of Depth Normalization for Small RNA Sequencing, Qin L-X, Zhou J, Shi J, et al., 2020
- Distinct response of the hepatic transcriptome to Aflatoxin B1 induced hepatocellular carcinogenesis and resistance in rats, Shi J, He J, Lin J, Sun X, Sun F, et al., 2016
- PEpiD: a prostate epigenetic database in mammals, Shi J, Hu J, Zhou Q, Du Y, and Jiang C, 2013
- Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells, Huang K, Zhang X, Shi J, Yao M, Lin J, et al., 2015
- Profiling analysis of histone modifications and gene expression in lewis lung carcinoma murine cells resistant to anti-VEGF treatment, Li D, Shi J, Du Y, Chen K, Liu Z, et al., 2016
- A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites, Chen Y, Zhang H, …, Shi J, et al., 2019
- Chromatin remodeling during in vivo neural stem cells differentiating to neurons in early Drosophila embryos, Ye Y, Gu L, Chen X, Shi J, et al., 2017
- Chromatin remodeling during the in vivo glial differentiation in early Drosophila embryos, Ye Y, Gu L, Chen X, Shi J, et al., 2016
- Molecular Characterization and Expression Pattern of Gene IGFBP-5 in the Cashmere Goat (Capra hircus), Wang X, Shi J, Yang J, Liang Y, et al., 2012
- Cloning and expression pattern of protein kinase B/AKT gene in Inner Mongolia Cashmere Goat, Yang J, Shi J, Liang Y, Zheng X, Zhang T, Qin Y, Wang Z, Liu D, 2011
- Molecular characterization and expression pattern of Rheb gene in Inner Mongolia cashmere goat (Capra hircus), Zheng X, Yang J, …, Shi J, et al., 2011
- Molecular cloning and characterization analysis of LEF-1 gene from Inner Mongolia Cashmere Goat, Zhang T, Wang Z, Li B, Shi J, Qin Y, et al., 2010
Awards
- 2014 Doctoral National Scholarship
- 2021 Selected for Shanghai Overseas High-Level Talent Introduction Plan
