2007-2011 Bachelor of Biotechnology: Inner Mongolia University
2011-2016 PhD in Biology: Tongji University
2014 Doctoral National Scholarship
Published paper on chromatin remodeling in Drosophila (Nucleic acids research, 2014)
2019-2021 Postdoctoral Fellow/Assistant Researcher at UC Irvine
2016-2019 Postdoctoral Fellow at Baylor College of Medicine
2013-2014 Visiting Scholar at Memorial Sloan-Kettering Cancer Center
2014 Doctoral National Scholarship
2021 Selected for Shanghai Overseas High-Level Talent Introduction Plan
Research
Epigenetic polymorphism in gene expression regulation Dynamics of epigenetic polymorphism in early development and aging Tumor epigenetic heterogeneity in early diagnosis and treatment Multi-omics deep mining to reveal disease molecular features
The Concurrence of DNA Methylation and Demethylation is Associated with Transcription Regulation, Shi J, Xu J, Chen EY, Li SJ, Cui Y, Shen L, Li JJ, and Li W, 2021
Cellular heterogeneity–adjusted clonal methylation (CHALM) provides better prediction of gene expression, Xu J, Shi J, Cui X, Cui Y, Li JJ, Goel A, Chen X, Su J, Issa J-P, and Li W, 2021
BAP1 links metabolic regulation of ferroptosis to tumour suppression, Zhang Y, Shi J, Liu X, Feng L, Gong Z, et al., 2018
H2A monoubiquitination links glucose availability to epigenetic regulation of the endoplasmic reticulum stress response and cancer cell death, Zhang Y, Shi J, Liu X, Xiao Z, et al., 2020
Drosophila Brahma complex remodels nucleosome organizations in multiple aspects, Shi J, Zheng M, Ye Y, Li M, Chen X, et al., 2014
Recognition of histone acetylation by the GAS41 YEATS domain promotes H2A.Z deposition in non-small cell lung cancer, Hsu CC, Shi J, Yuan C, Zhao D, Jiang S, et al., 2018
Gas41 links histone acetylation to H2A. Z deposition and maintenance of embryonic stem cell identity, Hsu CC, Zhao D, Shi J, Peng D, et al., 2018
Histone H3. 3 G34 Mutations Alter Histone H3K36 and H3K27 Methylation In Cis, Shi L, Shi J, Shi X, Li W, and Wen H, 2018
Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes, Xi Y, Shi J, Li W, Tanaka K, Allton KL, et al., 2018
CORM: An R Package Implementing the Clustering of Regression Models Method for Gene Clustering, Shi J, and Qin L-X, 2014
Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer, Liu X, Olszewski K, Zhang Y, Lim EW, Shi J, et al., 2020
Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer, Zheng ZY, Anurag M, Lei JT, …, Shi J, et al., 2020
S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling, Greco CM, Cervantes M, …, Shi J, et al., 2020
Defining the independence of the liver circadian clock, Koronowski KB, Kinouchi K, Welz PS, Smith JG, Zinna VM, Shi J, et al., 2019
The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3, Zhang Y, Xue Y, Shi J, Ahn JW, Mi W, et al., 2018
Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation, Gates LA, Shi J, Rohira AD, Feng Q, Zhu B, et al., 2017
The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate, Koppula P, Zhang Y, Shi J, Li W, and Gan B, 2017
Integration of Feeding Behaviour by the Liver Circadian Clock Reveals Network Dependency of Metabolic Rhythms, Greco CM, Koronowski KB, Smith JG, Shi J, et al., 2021
NG-Circos: next-generation Circos for data visualization and interpretation, Cui Y, Cui Z, Xu J, Hao D, Shi J, et al., 2020
Statistical Assessment of Depth Normalization for Small RNA Sequencing, Qin L-X, Zhou J, Shi J, et al., 2020
Distinct response of the hepatic transcriptome to Aflatoxin B1 induced hepatocellular carcinogenesis and resistance in rats, Shi J, He J, Lin J, Sun X, Sun F, et al., 2016
PEpiD: a prostate epigenetic database in mammals, Shi J, Hu J, Zhou Q, Du Y, and Jiang C, 2013
Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells, Huang K, Zhang X, Shi J, Yao M, Lin J, et al., 2015
Profiling analysis of histone modifications and gene expression in lewis lung carcinoma murine cells resistant to anti-VEGF treatment, Li D, Shi J, Du Y, Chen K, Liu Z, et al., 2016
A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites, Chen Y, Zhang H, …, Shi J, et al., 2019
Chromatin remodeling during in vivo neural stem cells differentiating to neurons in early Drosophila embryos, Ye Y, Gu L, Chen X, Shi J, et al., 2017
Chromatin remodeling during the in vivo glial differentiation in early Drosophila embryos, Ye Y, Gu L, Chen X, Shi J, et al., 2016
Molecular Characterization and Expression Pattern of Gene IGFBP-5 in the Cashmere Goat (Capra hircus), Wang X, Shi J, Yang J, Liang Y, et al., 2012
Cloning and expression pattern of protein kinase B/AKT gene in Inner Mongolia Cashmere Goat, Yang J, Shi J, Liang Y, Zheng X, Zhang T, Qin Y, Wang Z, Liu D, 2011
Molecular characterization and expression pattern of Rheb gene in Inner Mongolia cashmere goat (Capra hircus), Zheng X, Yang J, …, Shi J, et al., 2011
Molecular cloning and characterization analysis of LEF-1 gene from Inner Mongolia Cashmere Goat, Zhang T, Wang Z, Li B, Shi J, Qin Y, et al., 2010
Keywords
EpigeneticsPolymorphismGene ExpressionDevelopmentAgingTumor HeterogeneityDiagnosisTreatmentMulti-OmicsDisease Features
