Professor | Yaozu Xiang | Asia Growth Partners

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Name	Yaozu Xiang
Contact Information	yaozu.xiang@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Yaozu Xiang

Contact Information

yaozu.xiang@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	Bachelor and Master of Medicine: Tianjin University of Traditional Chinese Medicine PhD in Molecular Hematology: Imperial College London Postdoctoral Researcher: Yale University School of Medicine National Outstanding Youth Fund recipient Lead on national key research and development programs
Work Experience	Current - Tongji University - Professor and Director of the Department of Biomedical and Technology
Awards	ISTH Young Investigators Award NSTH Science Prize Imperial Rector’s Award

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

Bachelor and Master of Medicine: Tianjin University of Traditional Chinese Medicine
PhD in Molecular Hematology: Imperial College London
Postdoctoral Researcher: Yale University School of Medicine
National Outstanding Youth Fund recipient
Lead on national key research and development programs

Work Experience

Current - Tongji University - Professor and Director of the Department of Biomedical and Technology

Awards

ISTH Young Investigators Award
NSTH Science Prize
Imperial Rector’s Award

Areas of Focus	Cardiovascular diseases Integration of Chinese and Western medicine
Publications	Brazilin-Ce nanoparticles attenuate inflammation by de/anti-phosphorylation of IKKβ, Li S, Wang K, Jiang K, Xing D, Deng R, Xu Y, Ding Y, Guan H, Chen LL, Wang D, Chen Y, Bu W, Xiang Y, 2024 A transient wave of Bhlhe41+ resident macrophages enables remodeling of the developing infarcted myocardium, Xu Y, Jiang K, Su F, Deng R, Cheng Z, Wang D, Yu Y, Xiang Y, 2023 Structural repurposing of SGLT2 inhibitor empagliflozin for strengthening anti-heart failure activity with lower glycosuria, Xu Y, Zhang C, Jiang K, Yang X, Chen F, Cheng Z, Zhao J, Cheng J, Li X, Chen X, Zhou L, Duan H, Huang Y, Xiang Y, Li J, 2023 Anti-inflammatory effect of Danhong injection through inhibition of GSDMD-mediated pyroptosis, Li Y, Tu Z, Chen F, Yang X, Deng R, Su F, Cheng Z, Li S, Ong SB, Wang D, Chen Y, Xiang Y, 2023 Bone marrow-derived naïve B lymphocytes improve heart function after myocardial infarction: a novel cardioprotective mechanism for empagliflozin, Xu Y, Jiang K, Chen F, Qian J, Wang D, Wu Y, Zhou C, Yu Y, Chen K, Hwa J, Yang B, Wang H, Xiang Y, 2022 Gasdermin D inhibition confers antineutrophil-mediated cardioprotection in acute myocardial infarction, Jiang K, Tu Z, Chen K, Xu Y, Chen F, Xu S, Shi T, Qian J, Shen L, Hwa J, Wang D, Xiang Y, 2022 Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosis, Jiang K, Xu Y, Wang D, Chen F, Tu Z, Qian J, Xu S, Xu Y, Hwa J, Li J, Shang H, Xiang Y, 2022 The prokaryotic Argonaute proteins enhance homology sequence-directed recombination in bacteria, Fu L, Xie C, Jin Z, Tu Z, Han L, Jin M, Xiang Y, Zhang A, 2019 Diabetes Exacerbates Myocardial Ischemia/Reperfusion Injury by Down-Regulation of MicroRNA and Up-Regulation of O-GlcNAcylation, Wang D, Hu X, Lee SH, Chen F, Jiang K, Tu Z, Liu Z, Du J, Wang L, Yin C, Liao Y, Shang H, Martin KA, Herzog RI, Young LH, Qian L, Hwa J, Xiang Y, 2018 Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor, Xiang Y, Cheng J, Wang D, Hu X, Xie Y, Stitham J, Atteya G, Du J, Tang WH, Lee SH, Leslie K, Spollett G, Liu Z, Herzog E, Herzog RI, Lu J, Martin KA, Hwa J, 2015 Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13), Xiang Y, de Groot R, Crawley JT, Lane DA, 2011 Platelet activation, and antiplatelet targets and agents: current and novel strategies, Xiang YZ, Xia Y, Gao XM, Shang HC, Kang LY, Zhang BL, 2008

Areas of Focus

Cardiovascular diseases
Integration of Chinese and Western medicine

Publications

Brazilin-Ce nanoparticles attenuate inflammation by de/anti-phosphorylation of IKKβ, Li S, Wang K, Jiang K, Xing D, Deng R, Xu Y, Ding Y, Guan H, Chen LL, Wang D, Chen Y, Bu W, Xiang Y, 2024
A transient wave of Bhlhe41+ resident macrophages enables remodeling of the developing infarcted myocardium, Xu Y, Jiang K, Su F, Deng R, Cheng Z, Wang D, Yu Y, Xiang Y, 2023
Structural repurposing of SGLT2 inhibitor empagliflozin for strengthening anti-heart failure activity with lower glycosuria, Xu Y, Zhang C, Jiang K, Yang X, Chen F, Cheng Z, Zhao J, Cheng J, Li X, Chen X, Zhou L, Duan H, Huang Y, Xiang Y, Li J, 2023
Anti-inflammatory effect of Danhong injection through inhibition of GSDMD-mediated pyroptosis, Li Y, Tu Z, Chen F, Yang X, Deng R, Su F, Cheng Z, Li S, Ong SB, Wang D, Chen Y, Xiang Y, 2023
Bone marrow-derived naïve B lymphocytes improve heart function after myocardial infarction: a novel cardioprotective mechanism for empagliflozin, Xu Y, Jiang K, Chen F, Qian J, Wang D, Wu Y, Zhou C, Yu Y, Chen K, Hwa J, Yang B, Wang H, Xiang Y, 2022
Gasdermin D inhibition confers antineutrophil-mediated cardioprotection in acute myocardial infarction, Jiang K, Tu Z, Chen K, Xu Y, Chen F, Xu S, Shi T, Qian J, Shen L, Hwa J, Wang D, Xiang Y, 2022
Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosis, Jiang K, Xu Y, Wang D, Chen F, Tu Z, Qian J, Xu S, Xu Y, Hwa J, Li J, Shang H, Xiang Y, 2022
The prokaryotic Argonaute proteins enhance homology sequence-directed recombination in bacteria, Fu L, Xie C, Jin Z, Tu Z, Han L, Jin M, Xiang Y, Zhang A, 2019
Diabetes Exacerbates Myocardial Ischemia/Reperfusion Injury by Down-Regulation of MicroRNA and Up-Regulation of O-GlcNAcylation, Wang D, Hu X, Lee SH, Chen F, Jiang K, Tu Z, Liu Z, Du J, Wang L, Yin C, Liao Y, Shang H, Martin KA, Herzog RI, Young LH, Qian L, Hwa J, Xiang Y, 2018
Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor, Xiang Y, Cheng J, Wang D, Hu X, Xie Y, Stitham J, Atteya G, Du J, Tang WH, Lee SH, Leslie K, Spollett G, Liu Z, Herzog E, Herzog RI, Lu J, Martin KA, Hwa J, 2015
Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13), Xiang Y, de Groot R, Crawley JT, Lane DA, 2011
Platelet activation, and antiplatelet targets and agents: current and novel strategies, Xiang YZ, Xia Y, Gao XM, Shang HC, Kang LY, Zhang BL, 2008

Cardiovascular Biology Pharmacology Coronary Heart Disease Traditional Chinese Medicine Western Medicine Intervention Research Disease Mechanism Molecular Hematology Biomedical Technology

Yaozu Xiang - Tongji University

Ji Huang - Shanghai Normal University

Qing-Ping Yao - Shanghai Jiao Tong University

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