Upload Avatar (500 x 500)
项耀祖
Life Science
同济大学
上海
Language: 中文, 英语
心血管
生物学
药理学
冠心病
中医
西医
干预研究
病机
分子血液学
生物医药技术
Areas of Focus
- 心血管疾病
- 中西医结合
Work Experience
- 现任 - 同济大学 - 生物医药与技术系系主任
Academic Background & Achievements
- 医学学士、医学硕士：天津中医药大学
- 分子血液学博士：英国帝国理工学院
- 博士后：美国耶鲁大学医学院
- 国家优青获得者
- 主持国家重点研发计划课题
Publications
- Brazilin-Ce nanoparticles attenuate inflammation by de/anti-phosphorylation of IKKβ, Li S, Wang K, Jiang K, Xing D, Deng R, Xu Y, Ding Y, Guan H, Chen LL, Wang D, Chen Y, Bu W, Xiang Y, 2024
- A transient wave of Bhlhe41+ resident macrophages enables remodeling of the developing infarcted myocardium, Xu Y, Jiang K, Su F, Deng R, Cheng Z, Wang D, Yu Y, Xiang Y, 2023
- Structural repurposing of SGLT2 inhibitor empagliflozin for strengthening anti-heart failure activity with lower glycosuria, Xu Y, Zhang C, Jiang K, Yang X, Chen F, Cheng Z, Zhao J, Cheng J, Li X, Chen X, Zhou L, Duan H, Huang Y, Xiang Y, Li J, 2023
- Anti-inflammatory effect of Danhong injection through inhibition of GSDMD-mediated pyroptosis, Li Y, Tu Z, Chen F, Yang X, Deng R, Su F, Cheng Z, Li S, Ong SB, Wang D, Chen Y, Xiang Y, 2023
- Bone marrow-derived naïve B lymphocytes improve heart function after myocardial infarction: a novel cardioprotective mechanism for empagliflozin, Xu Y, Jiang K, Chen F, Qian J, Wang D, Wu Y, Zhou C, Yu Y, Chen K, Hwa J, Yang B, Wang H, Xiang Y, 2022
- Gasdermin D inhibition confers antineutrophil-mediated cardioprotection in acute myocardial infarction, Jiang K, Tu Z, Chen K, Xu Y, Chen F, Xu S, Shi T, Qian J, Shen L, Hwa J, Wang D, Xiang Y, 2022
- Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosis, Jiang K, Xu Y, Wang D, Chen F, Tu Z, Qian J, Xu S, Xu Y, Hwa J, Li J, Shang H, Xiang Y, 2022
- The prokaryotic Argonaute proteins enhance homology sequence-directed recombination in bacteria, Fu L, Xie C, Jin Z, Tu Z, Han L, Jin M, Xiang Y, Zhang A, 2019
- Diabetes Exacerbates Myocardial Ischemia/Reperfusion Injury by Down-Regulation of MicroRNA and Up-Regulation of O-GlcNAcylation, Wang D, Hu X, Lee SH, Chen F, Jiang K, Tu Z, Liu Z, Du J, Wang L, Yin C, Liao Y, Shang H, Martin KA, Herzog RI, Young LH, Qian L, Hwa J, Xiang Y, 2018
- Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor, Xiang Y, Cheng J, Wang D, Hu X, Xie Y, Stitham J, Atteya G, Du J, Tang WH, Lee SH, Leslie K, Spollett G, Liu Z, Herzog E, Herzog RI, Lu J, Martin KA, Hwa J, 2015
- Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13), Xiang Y, de Groot R, Crawley JT, Lane DA, 2011
- Platelet activation, and antiplatelet targets and agents: current and novel strategies, Xiang YZ, Xia Y, Gao XM, Shang HC, Kang LY, Zhang BL, 2008
Awards
- ISTH青年研究者奖
- NSTH科学奖
- 帝国校长奖
