Professor | Ying Jiang | Asia Growth Partners

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Name	Ying Jiang
Contact Information	ying_jiang@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Ying Jiang

Contact Information

ying_jiang@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2004 - Bachelor's Degree: Nanjing University, School of Life Sciences 2013 - PhD: University of Rochester, Department of Biology Published over 10 papers as first or corresponding author in journals like PNAS, Nucleic Acids Res., Oncogene, JBC
Work Experience	2013 - Present: Tongji University, School of Life Science and Technology - Assistant Researcher, Associate Researcher, Associate Professor

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2004 - Bachelor's Degree: Nanjing University, School of Life Sciences
2013 - PhD: University of Rochester, Department of Biology
Published over 10 papers as first or corresponding author in journals like PNAS, Nucleic Acids Res., Oncogene, JBC

Work Experience

2013 - Present: Tongji University, School of Life Science and Technology - Assistant Researcher, Associate Researcher, Associate Professor

Areas of Focus	Breast cancer and gynecological tumors related DNA repair regulation mechanisms Targeted DNA repair prevention and treatment methods for breast cancer and gynecological tumors
Publications	Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PKcs inhibitors, Wang C, Tang H, Geng A, Dai B, Zhang H, Sun X, Chen Y, Qiao Z, Zhu H, Yang J, Chen J, He Q, Qin N, Xie J, Tan R, Wan X, Gao S, Jiang Y, Sun FL, Mao Z, 2020 A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites, Chen Y, Zhang H, Xu Z, Tang H, Geng A, Cai B, SuT, ShiJ, Jiang C, Tian X, SeluanovA, HuangJ, WanX, Jiang Y, Gorbunova V,Mao Z, 2019 The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression, Zhang F, Tang H, Jiang Y,Mao Z, 2017 Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy, Chen Y, Li Z, Xu Z, Tang H, Guo W, Sun X, Zhang W, Zhang J, Wan X, Jiang Y,Mao Z, 2018 POT1 inhibits the efficiency but promotes the fidelity of nonhomologous end joining at non-telomeric DNA regions, Yu Y, Tang R, Ren Q, Gao B, Sheng Z, Zhang J, Zheng X, Jiang Y, Li Lan,Mao Z, 2017 Diosmetin enhances the sensitivity of radiotherapy by suppressing homologous recombination in endometrial cancer, Hu Z, Cai B, Wang M, Wen X, Geng A, Hu X, Xue R, Mao Z, Jiang Y, Wan X, 2020 Triptolide impairs genome integrity by directly blocking the enzymatic activity of DNA-PKcs in human cells, Cai B, Hu Z, Tang H, Hu Z, Mao Z, Liu B, Xu X, Jiang Y, Wan X, 2020 Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells, Zhang L, Zhang F, Zhang W, Chen L, Gao N, Men Y, Xu X, Jiang Y, 2015 Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells, Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L, 2013 DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells, Mao Z#, Jiang Y#, Liu X, Seluanov A, Gorbunova V, 2009

Areas of Focus

Breast cancer and gynecological tumors related DNA repair regulation mechanisms
Targeted DNA repair prevention and treatment methods for breast cancer and gynecological tumors

Publications

Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PKcs inhibitors, Wang C, Tang H, Geng A, Dai B, Zhang H, Sun X, Chen Y, Qiao Z, Zhu H, Yang J, Chen J, He Q, Qin N, Xie J, Tan R, Wan X, Gao S, Jiang Y*, Sun FL*, Mao Z*, 2020
A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites, Chen Y, Zhang H, Xu Z, Tang H, Geng A, Cai B, SuT, ShiJ, Jiang C, Tian X, SeluanovA, HuangJ, WanX, Jiang Y*, Gorbunova V*,Mao Z*, 2019
The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression, Zhang F, Tang H, Jiang Y*,Mao Z*, 2017
Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy, Chen Y, Li Z, Xu Z, Tang H, Guo W, Sun X, Zhang W, Zhang J, Wan X, Jiang Y*,Mao Z*, 2018
POT1 inhibits the efficiency but promotes the fidelity of nonhomologous end joining at non-telomeric DNA regions, Yu Y, Tang R, Ren Q, Gao B, Sheng Z, Zhang J, Zheng X, Jiang Y*, Li Lan*,Mao Z*, 2017
Diosmetin enhances the sensitivity of radiotherapy by suppressing homologous recombination in endometrial cancer, Hu Z, Cai B, Wang M, Wen X, Geng A, Hu X, Xue R, Mao Z, Jiang Y*, Wan X*, 2020
Triptolide impairs genome integrity by directly blocking the enzymatic activity of DNA-PKcs in human cells, Cai B, Hu Z, Tang H, Hu Z, Mao Z, Liu B, Xu X, Jiang Y*, Wan X*, 2020
Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells, Zhang L, Zhang F, Zhang W, Chen L, Gao N, Men Y, Xu X, Jiang Y*, 2015
Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells, Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L, 2013
DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells, Mao Z#, Jiang Y#, Liu X, Seluanov A, Gorbunova V, 2009

Dna Repair Breast Cancer Gynecological Tumors Regulation Mechanisms Targeted Therapy Prevention Treatment Methods Cell Models Animal Models Parp1

Ying Jiang - Tongji University

Zhengmao Hu - Central South University

Zhongbing Lu - University of Chinese Academy of Sciences

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