Professor | Anke Geng | Asia Growth Partners

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Name	Anke Geng
Contact Information	anke_geng@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

Upload Avatar (500 x 500)

Name

Anke Geng

Contact Information

anke_geng@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2020 - PhD in Biology: Tongji University Supervised by Professor Mao Zhiyong Hosted National Natural Science Foundation Youth Project (2021) Hosted Shanghai Science and Technology Committee Sail Plan (2021) Received Shanghai Medical Science and Technology Award (2021) Received Outstanding Doctoral Dissertation at Tongji University (2022)
Work Experience	2020-09 - Present: Tongji University, Research Intern, Assistant Researcher, Pre-appointed Assistant Professor
Awards	Shanghai Medical Science and Technology Award (2021): Detail not specified Outstanding Doctoral Dissertation at Tongji University (2022): Detail not specified

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2020 - PhD in Biology: Tongji University
Supervised by Professor Mao Zhiyong
Hosted National Natural Science Foundation Youth Project (2021)
Hosted Shanghai Science and Technology Committee Sail Plan (2021)
Received Shanghai Medical Science and Technology Award (2021)
Received Outstanding Doctoral Dissertation at Tongji University (2022)

Work Experience

2020-09 - Present: Tongji University, Research Intern, Assistant Researcher, Pre-appointed Assistant Professor

Awards

Shanghai Medical Science and Technology Award (2021): Detail not specified
Outstanding Doctoral Dissertation at Tongji University (2022): Detail not specified

Areas of Focus	Mechanisms of longevity-related DNA repair and genome stability New functions of longevity genes in maintaining genome stability Mechanisms by which longevity organisms maintain genome stability Targeted genome stability interventions for aging and related diseases
Publications	SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner, Geng A, Sun J, Tang H, Yu Y, Wang X, Zhang J, Wang X, Sun X, Zhou X, Gao N, Tan R, Xu Z, Jiang Y, Mao Z, 2024 The deacetylase SIRT6 promotes the repair of UV-induced DNA damage by targeting DDB2, Geng A, Tang H, Huang J, Qian Z, Qin N, Yao Y, Xu Z, Chen H, Lan L, Xie H, Zhang J, Jiang Y, Mao Z, 2020 Single senescent cell sequencing reveals heterogeneity in senescent cells induced by telomere erosion, Tang H, Geng A, Zhang T, Wang C, Jiang Y, Mao Z, 2019 Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PK inhibitors, Wang C, Tang H, Geng A, Dai B, Zhang H, Sun X, Chen Y, Qiao Z, Zhu H, Yang J, Chen J, He Q, Qin N, Xie J, Tan R, Wan X, Gao S, Jiang Y, Sun F, Mao Z, 2020 Chrysin impairs genomic stability by suppressing DNA double-strand break repair in breast cancer cells, Geng A, Xu S, Yao Y, Qian Z, Wang X, Sun J, Zhang J, Shi F, Chen Z, Zhang W, Mao Z, Lu W, Jiang Y, 2022 Tanshinone I suppresses hepatocellular carcinoma cells growth through targeting DNA double-strand break repair, Qian Z, Feng N, Geng A, 2023

Areas of Focus

Mechanisms of longevity-related DNA repair and genome stability
New functions of longevity genes in maintaining genome stability
Mechanisms by which longevity organisms maintain genome stability
Targeted genome stability interventions for aging and related diseases

Publications

SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner, Geng A, Sun J, Tang H, Yu Y, Wang X, Zhang J, Wang X, Sun X, Zhou X, Gao N, Tan R, Xu Z, Jiang Y, Mao Z, 2024
The deacetylase SIRT6 promotes the repair of UV-induced DNA damage by targeting DDB2, Geng A, Tang H, Huang J, Qian Z, Qin N, Yao Y, Xu Z, Chen H, Lan L, Xie H, Zhang J, Jiang Y, Mao Z, 2020
Single senescent cell sequencing reveals heterogeneity in senescent cells induced by telomere erosion, Tang H, Geng A, Zhang T, Wang C, Jiang Y, Mao Z, 2019
Rational combination therapy for hepatocellular carcinoma with PARP1 and DNA-PK inhibitors, Wang C, Tang H, Geng A, Dai B, Zhang H, Sun X, Chen Y, Qiao Z, Zhu H, Yang J, Chen J, He Q, Qin N, Xie J, Tan R, Wan X, Gao S, Jiang Y, Sun F, Mao Z, 2020
Chrysin impairs genomic stability by suppressing DNA double-strand break repair in breast cancer cells, Geng A, Xu S, Yao Y, Qian Z, Wang X, Sun J, Zhang J, Shi F, Chen Z, Zhang W, Mao Z, Lu W, Jiang Y, 2022
Tanshinone I suppresses hepatocellular carcinoma cells growth through targeting DNA double-strand break repair, Qian Z, Feng N, Geng A, 2023

Longevity Dna Repair Genome Stability Molecular Mechanisms Sirtuins Aging Disease Intervention Biomedical Research Gene Therapy Cellular Senescence

Le Rongrong - Tongji University

Changdong Lin - Tongji University

Zhiyong Mao - Tongji University

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