Professor | Yuan Kai | Asia Growth Partners

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Name	Yuan Kai
Contact Information	yuankai@csu.edu.cn
Language ability	Chinese, English
Province	Hunan

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Name

Yuan Kai

Contact Information

yuankai@csu.edu.cn

Language ability

Chinese, English

Province

Hunan

University/Lab Affiliation and Title	Central South University
Faculty	Life Sciences
Academic Background & Achievements	2000.9-2004.7 Bachelor of Science: University of Science and Technology of China, School of Life Sciences 2004.9-2009.12 Doctor of Science: University of Science and Technology of China, Department of Cell and Molecular Biology
Work Experience	2010.4-2016.3 Postdoctoral Researcher, Department of Biochemistry, University of California, San Francisco 2016.4-2017.1 Specialist, Department of Biochemistry, University of California, San Francisco 2017.2-present Researcher, Institute of Precision Molecular Medicine, Xiangya Hospital, Central South University 2019.11-present Director, Clinical Biobank Center, Xiangya Hospital, Central South University
Awards	Member of the Innovation Team of the Hunan High-level Talent Gathering Project (2019) National Overseas High-level Talent Introduction Plan (2017) Hunan Science and Technology Innovation Platform and Talent Plan-Outstanding Talent (2017) Hunan Youth Talent (2017) CTSI-SOS Award for Junior Investigator – UCSF (2014) PBBR Award – UCSF (2014) Chinese Academy of Sciences President's Award (Excellence) (2009) Zhu Li Yuehua Scholarship for Doctoral Students, Chinese Academy of Sciences (2008) Hong Kong 'Qiushi' Scholarship (2007)

University/Lab Affiliation and Title

Central South University

Faculty

Life Sciences

Academic Background & Achievements

2000.9-2004.7 Bachelor of Science: University of Science and Technology of China, School of Life Sciences
2004.9-2009.12 Doctor of Science: University of Science and Technology of China, Department of Cell and Molecular Biology

Work Experience

2010.4-2016.3 Postdoctoral Researcher, Department of Biochemistry, University of California, San Francisco
2016.4-2017.1 Specialist, Department of Biochemistry, University of California, San Francisco
2017.2-present Researcher, Institute of Precision Molecular Medicine, Xiangya Hospital, Central South University
2019.11-present Director, Clinical Biobank Center, Xiangya Hospital, Central South University

Awards

Member of the Innovation Team of the Hunan High-level Talent Gathering Project (2019)
National Overseas High-level Talent Introduction Plan (2017)
Hunan Science and Technology Innovation Platform and Talent Plan-Outstanding Talent (2017)
Hunan Youth Talent (2017)
CTSI-SOS Award for Junior Investigator – UCSF (2014)
PBBR Award – UCSF (2014)
Chinese Academy of Sciences President's Award (Excellence) (2009)
Zhu Li Yuehua Scholarship for Doctoral Students, Chinese Academy of Sciences (2008)
Hong Kong 'Qiushi' Scholarship (2007)

Areas of Focus	Tumor Cell Biology Developmental Cell Biology Epigenetics
Publications	Functional reciprocity of proteins involved in mitosis and endocytosis, Yu H, Li Y, Li L, Huang J, Wang X, Tang R, Jiang Z, Lv L, Chen F, Yu C, Yuan K, 2020 Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate Mid-Blastula Transition events at a low nuclear-cytoplasmic ratio, Strong I, Lei X, Chen F, Yuan K, O’Farrell P, 2020 The kinase activity of Drosophila BubR1 is required for insulin signaling-dependent stem cell maintenance, Tang R, Jiang Z, Chen F, Yu W, Fan K, Tan J, Zhang Z, Liu X, Li P, Yuan K, 2020 Timing the Drosophila Mid-Blastula Transition: a cell cycle-centered view, Yuan K, Seller CA, Shermoen AW, O’Farrell PH, 2016 TALE-light imaging reveals maternally-guided, H3K9me2/3-independent emergence of functional heterochromatin in Drosophila embryos, Yuan K, O’Farrell PH, 2016 Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition, Yuan K, O’Farrell PH, 2015 Illuminating DNA replication during Drosophila development using TALE-lights, Yuan K, Shermoen AW, O’Farrell PH, 2014 Different cyclin-types collaborate to reverse the S phase checkpoint and permit prompt mitosis, Yuan K, Farrell JA, O’Farrell PH, 2012 Illumination of mitotic orchestra during cell division: A polo view, Yuan K, Huang Y, Yao X, 2011 PinX1 is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation, Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw AP, Thomas K, Zhang J, Mann D, Liao J, Jin C, Yao X, 2009 Recruitment of separase to mitotic chromosomes is regulated by Aurora B, Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C, Yao X, 2009 Phospho-regulation of HsCDC14A by polo-like kinase 1 is essential for mitotic progression, Yuan K, Hu H, Guo Z, Fu G, Shaw AP, Hu R, Yao X, 2007

Areas of Focus

Tumor Cell Biology
Developmental Cell Biology
Epigenetics

Publications

Functional reciprocity of proteins involved in mitosis and endocytosis, Yu H, Li Y, Li L, Huang J, Wang X, Tang R, Jiang Z, Lv L, Chen F, Yu C, Yuan K, 2020
Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate Mid-Blastula Transition events at a low nuclear-cytoplasmic ratio, Strong I, Lei X, Chen F, Yuan K, O’Farrell P, 2020
The kinase activity of Drosophila BubR1 is required for insulin signaling-dependent stem cell maintenance, Tang R, Jiang Z, Chen F, Yu W, Fan K, Tan J, Zhang Z, Liu X, Li P, Yuan K, 2020
Timing the Drosophila Mid-Blastula Transition: a cell cycle-centered view, Yuan K, Seller CA, Shermoen AW, O’Farrell PH, 2016
TALE-light imaging reveals maternally-guided, H3K9me2/3-independent emergence of functional heterochromatin in Drosophila embryos, Yuan K, O’Farrell PH, 2016
Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition, Yuan K, O’Farrell PH, 2015
Illuminating DNA replication during Drosophila development using TALE-lights, Yuan K, Shermoen AW, O’Farrell PH, 2014
Different cyclin-types collaborate to reverse the S phase checkpoint and permit prompt mitosis, Yuan K, Farrell JA, O’Farrell PH, 2012
Illumination of mitotic orchestra during cell division: A polo view, Yuan K, Huang Y, Yao X, 2011
PinX1 is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation, Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw AP, Thomas K, Zhang J, Mann D, Liao J, Jin C, Yao X, 2009
Recruitment of separase to mitotic chromosomes is regulated by Aurora B, Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C, Yao X, 2009
Phospho-regulation of HsCDC14A by polo-like kinase 1 is essential for mitotic progression, Yuan K, Hu H, Guo Z, Fu G, Shaw AP, Hu R, Yao X, 2007

Cancer Cell Signaling Gene Expression Embryonic Development Molecular Mechanisms Genomics High-Throughput Screening Crispr Disease Intervention Biomarkers

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