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Yuan Kai
Life Science
Central South University
Hunan
Language: Chinese, English
Cancer
Cell Signaling
Gene Expression
Embryonic Development
Molecular Mechanisms
Genomics
High-Throughput Screening
Crispr
Disease Intervention
Biomarkers
Areas of Focus
- Tumor Cell Biology
- Developmental Cell Biology
- Epigenetics
Work Experience
- 2010.4-2016.3 Postdoctoral Researcher, Department of Biochemistry, University of California, San Francisco
- 2016.4-2017.1 Specialist, Department of Biochemistry, University of California, San Francisco
- 2017.2-present Researcher, Institute of Precision Molecular Medicine, Xiangya Hospital, Central South University
- 2019.11-present Director, Clinical Biobank Center, Xiangya Hospital, Central South University
Academic Background & Achievements
- 2000.9-2004.7 Bachelor of Science: University of Science and Technology of China, School of Life Sciences
- 2004.9-2009.12 Doctor of Science: University of Science and Technology of China, Department of Cell and Molecular Biology
Publications
- Functional reciprocity of proteins involved in mitosis and endocytosis, Yu H, Li Y, Li L, Huang J, Wang X, Tang R, Jiang Z, Lv L, Chen F, Yu C, Yuan K, 2020
- Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate Mid-Blastula Transition events at a low nuclear-cytoplasmic ratio, Strong I, Lei X, Chen F, Yuan K, O’Farrell P, 2020
- The kinase activity of Drosophila BubR1 is required for insulin signaling-dependent stem cell maintenance, Tang R, Jiang Z, Chen F, Yu W, Fan K, Tan J, Zhang Z, Liu X, Li P, Yuan K, 2020
- Timing the Drosophila Mid-Blastula Transition: a cell cycle-centered view, Yuan K, Seller CA, Shermoen AW, O’Farrell PH, 2016
- TALE-light imaging reveals maternally-guided, H3K9me2/3-independent emergence of functional heterochromatin in Drosophila embryos, Yuan K, O’Farrell PH, 2016
- Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition, Yuan K, O’Farrell PH, 2015
- Illuminating DNA replication during Drosophila development using TALE-lights, Yuan K, Shermoen AW, O’Farrell PH, 2014
- Different cyclin-types collaborate to reverse the S phase checkpoint and permit prompt mitosis, Yuan K, Farrell JA, O’Farrell PH, 2012
- Illumination of mitotic orchestra during cell division: A polo view, Yuan K, Huang Y, Yao X, 2011
- PinX1 is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation, Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw AP, Thomas K, Zhang J, Mann D, Liao J, Jin C, Yao X, 2009
- Recruitment of separase to mitotic chromosomes is regulated by Aurora B, Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C, Yao X, 2009
- Phospho-regulation of HsCDC14A by polo-like kinase 1 is essential for mitotic progression, Yuan K, Hu H, Guo Z, Fu G, Shaw AP, Hu R, Yao X, 2007
Awards
- Member of the Innovation Team of the Hunan High-level Talent Gathering Project (2019)
- National Overseas High-level Talent Introduction Plan (2017)
- Hunan Science and Technology Innovation Platform and Talent Plan-Outstanding Talent (2017)
- Hunan Youth Talent (2017)
- CTSI-SOS Award for Junior Investigator – UCSF (2014)
- PBBR Award – UCSF (2014)
- Chinese Academy of Sciences President's Award (Excellence) (2009)
- Zhu Li Yuehua Scholarship for Doctoral Students, Chinese Academy of Sciences (2008)
- Hong Kong 'Qiushi' Scholarship (2007)
