Professor | 袁凯 | 数字化转型顾问

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Name	袁凯
Contact Information	yuankai@csu.edu.cn
Language ability	中文, 英语
Province	湖南省

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Name

袁凯

Contact Information

yuankai@csu.edu.cn

Language ability

中文, 英语

Province

湖南省

University/Lab Affiliation and Title	中南大学
Faculty	Life Sciences
Academic Background & Achievements	2000.9-2004.7 中国科学技术大学生命科学学院理学学士 2004.9-2009.12 中国科学技术大学细胞与分子生物学系理学博士
Work Experience	2010.4-2016.3 美国加州大学旧金山分校生物化学系博士后 2016.4-2017.1 美国加州大学旧金山分校生物化学系Specialist 2017.2-至今中南大学湘雅医院精准分子医学研究所研究员 2019.11-至今中南大学湘雅医院临床生物样本中心主任
Awards	湖湘高层次人才聚集工程创新团队成员（2019）国家海外高层次人才引进计划（2017）湖南省科技创新平台与人才计划-优秀人才（2017）湖湘青年英才（2017） The Clinical & Translational Science Institute (CTSI)-Strategic Opportunities Support (SOS) Award for Junior Investigator –UCSF（2014） Program for Breakthrough Biomedical Research (PBBR) Award –UCSF（2014）中国科学院院长奖（优秀奖）（2009）中国科学院朱李月华博士研究生奖学金（2008）香港“求是”奖学金（2007）

University/Lab Affiliation and Title

中南大学

Faculty

Life Sciences

Academic Background & Achievements

2000.9-2004.7 中国科学技术大学生命科学学院理学学士
2004.9-2009.12 中国科学技术大学细胞与分子生物学系理学博士

Work Experience

2010.4-2016.3 美国加州大学旧金山分校生物化学系博士后
2016.4-2017.1 美国加州大学旧金山分校生物化学系Specialist
2017.2-至今中南大学湘雅医院精准分子医学研究所研究员
2019.11-至今中南大学湘雅医院临床生物样本中心主任

Awards

湖湘高层次人才聚集工程创新团队成员（2019）
国家海外高层次人才引进计划（2017）
湖南省科技创新平台与人才计划-优秀人才（2017）
湖湘青年英才（2017）
The Clinical & Translational Science Institute (CTSI)-Strategic Opportunities Support (SOS) Award for Junior Investigator –UCSF（2014）
Program for Breakthrough Biomedical Research (PBBR) Award –UCSF（2014）
中国科学院院长奖（优秀奖）（2009）
中国科学院朱李月华博士研究生奖学金（2008）
香港“求是”奖学金（2007）

Areas of Focus	肿瘤细胞生物学发育细胞生物学表观遗传学
Publications	Functional reciprocity of proteins involved in mitosis and endocytosis, Yu H, Li Y, Li L, Huang J, Wang X, Tang R, Jiang Z, Lv L, Chen F, Yu C, Yuan K, 2020 Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate Mid-Blastula Transition events at a low nuclear-cytoplasmic ratio, Strong I, Lei X, Chen F, Yuan K, O’Farrell P, 2020 The kinase activity of Drosophila BubR1 is required for insulin signaling-dependent stem cell maintenance, Tang R, Jiang Z, Chen F, Yu W, Fan K, Tan J, Zhang Z, Liu X, Li P, Yuan K, 2020 Timing the Drosophila Mid-Blastula Transition: a cell cycle-centered view, Yuan K, Seller CA, Shermoen AW, O’Farrell PH, 2016 TALE-light imaging reveals maternally-guided, H3K9me2/3-independent emergence of functional heterochromatin in Drosophila embryos, Yuan K, O’Farrell PH, 2016 Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition, Yuan K, O’Farrell PH, 2015 Illuminating DNA replication during Drosophila development using TALE-lights, Yuan K, Shermoen AW, O’Farrell PH, 2014 Different cyclin-types collaborate to reverse the S phase checkpoint and permit prompt mitosis, Yuan K, Farrell JA, O’Farrell PH, 2012 Illumination of mitotic orchestra during cell division: A polo view, Yuan K, Huang Y, Yao X, 2011 PinX1 is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation, Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw AP, Thomas K, Zhang J, Mann D, Liao J, Jin C, Yao X, 2009 Recruitment of separase to mitotic chromosomes is regulated by Aurora B, Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C, Yao X, 2009 Phospho-regulation of HsCDC14A by polo-like kinase 1 is essential for mitotic progression, Yuan K, Hu H, Guo Z, Fu G, Shaw AP, Hu R, Yao X, 2007

Areas of Focus

肿瘤细胞生物学
发育细胞生物学
表观遗传学

Publications

Functional reciprocity of proteins involved in mitosis and endocytosis, Yu H, Li Y, Li L, Huang J, Wang X, Tang R, Jiang Z, Lv L, Chen F, Yu C, Yuan K, 2020
Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate Mid-Blastula Transition events at a low nuclear-cytoplasmic ratio, Strong I, Lei X, Chen F, Yuan K, O’Farrell P, 2020
The kinase activity of Drosophila BubR1 is required for insulin signaling-dependent stem cell maintenance, Tang R, Jiang Z, Chen F, Yu W, Fan K, Tan J, Zhang Z, Liu X, Li P, Yuan K, 2020
Timing the Drosophila Mid-Blastula Transition: a cell cycle-centered view, Yuan K, Seller CA, Shermoen AW, O’Farrell PH, 2016
TALE-light imaging reveals maternally-guided, H3K9me2/3-independent emergence of functional heterochromatin in Drosophila embryos, Yuan K, O’Farrell PH, 2016
Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition, Yuan K, O’Farrell PH, 2015
Illuminating DNA replication during Drosophila development using TALE-lights, Yuan K, Shermoen AW, O’Farrell PH, 2014
Different cyclin-types collaborate to reverse the S phase checkpoint and permit prompt mitosis, Yuan K, Farrell JA, O’Farrell PH, 2012
Illumination of mitotic orchestra during cell division: A polo view, Yuan K, Huang Y, Yao X, 2011
PinX1 is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation, Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw AP, Thomas K, Zhang J, Mann D, Liao J, Jin C, Yao X, 2009
Recruitment of separase to mitotic chromosomes is regulated by Aurora B, Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C, Yao X, 2009
Phospho-regulation of HsCDC14A by polo-like kinase 1 is essential for mitotic progression, Yuan K, Hu H, Guo Z, Fu G, Shaw AP, Hu R, Yao X, 2007

癌症细胞信号基因表达胚胎发育分子机制基因组学高通量筛选 Crispr 疾病干预生物标志物

刘琦 - 同济大学

肖毅 - 上海交通大学

袁凯 - 中南大学

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