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Feng Li
Medical School
Wuhan University
Hubei
Language: English, Chinese
Tumor
Therapy
Targeted
Epigenetics
Signaling
Protein
Identification
Subcellular
Genesis
Pathophysiology
Areas of Focus
- Tumor targeted therapy
- Epigenetic-based targeted therapy research
- Tumor cell signaling pathway protein complex identification and function
- Novel subcellular structure genesis and pathophysiological function
Work Experience
- 2008-2013: Postdoctoral Researcher at University of Kentucky College of Medicine
- 2013-present: Professor at Wuhan University, Department of Medical Genetics
Academic Background & Achievements
- 1998-2002: Bachelor's Degree from Huazhong Agricultural University
- 2002-2008: Joint PhD program at Huazhong Agricultural University & Institute of Biophysics, Chinese Academy of Sciences
Publications
- Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer, Feng Li et al., 2024
- KDM5C mediated recruitment of BRD4 to chromatin regulates enhancer activation and BET inhibitor sensitivity, Feng Li et al., 2024
- A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis (NASH) in mice via binding and relocating acetyl-coA carboxylase, Feng Li et al., 2023
- Oncogenic BRAF noncanonically promotes tumor metastasis by mediating VASP phosphorylation and filopodia formation, Feng Li et al., 2023
- The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region, Feng Li et al., 2023
- Deficiency of the X-inactivation escaping gene KDM5C in clear cell renal cell carcinoma promotes tumorigenicity by reprogramming glycogen metabolism and inhibiting ferroptosis, Feng Li et al., 2021
- Detectable Serum Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load (RNAemia) Is Closely Correlated With Drastically Elevated Interleukin 6 Level in Critically Ill Patients With Coronavirus Disease 2019, Feng Li et al., 2020
- Histone demethylase KDM4B promotes DNA damage by activating long interspersed nuclear element-1, Feng Li et al., 2019
- E6 Protein Expressed by High-Risk HPV Activates Super-Enhancers of the EGFR and c-MET Oncogenes by Destabilizing the Histone Demethylase KDM5C, Feng Li et al., 2018
- Regulation of Mismatch Repair by Histone Code and Posttranslational Modifications in Eukaryotic Cells, Feng Li et al., 2016
- The histone mark H3K36me3 regulate human mismatch repair through its interaction with MutSalpha, Feng Li et al., 2013
