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李枫
Medical School
武汉大学
湖北省
Language: 英语, 汉语
肿瘤
治疗
靶向
表观遗传学
信号
蛋白
鉴定
亚细胞
发生
病理生理
Areas of Focus
- 肿瘤靶向治疗
- 基于肿瘤表观遗传的靶向治疗研究
- 肿瘤细胞信号通路蛋白复合物的鉴定和功能研究
- 新型亚细胞结构的发生机制与病理生理功能研究
Work Experience
- 2008-2013: University of Kentucky College of Medicine, 博士后
- 2013-至今: 武汉大学医学遗传学系，教授、博导
Academic Background & Achievements
- 1998-2002: 华中农业大学，学士学位
- 2002-2008: 华中农业大学&中国科学院生物物理研究所联合培养，硕博连读
Publications
- Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer, 李枫 等., 2024
- KDM5C mediated recruitment of BRD4 to chromatin regulates enhancer activation and BET inhibitor sensitivity, 李枫 等., 2024
- A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis (NASH) in mice via binding and relocating acetyl-coA carboxylase, 李枫 等., 2023
- Oncogenic BRAF noncanonically promotes tumor metastasis by mediating VASP phosphorylation and filopodia formation, 李枫 等., 2023
- The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region, 李枫 等., 2023
- Deficiency of the X-inactivation escaping gene KDM5C in clear cell renal cell carcinoma promotes tumorigenicity by reprogramming glycogen metabolism and inhibiting ferroptosis, 李枫 等., 2021
- Detectable Serum Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load (RNAemia) Is Closely Correlated With Drastically Elevated Interleukin 6 Level in Critically Ill Patients With Coronavirus Disease 2019, 李枫 等., 2020
- Histone demethylase KDM4B promotes DNA damage by activating long interspersed nuclear element-1, 李枫 等., 2019
- E6 Protein Expressed by High-Risk HPV Activates Super-Enhancers of the EGFR and c-MET Oncogenes by Destabilizing the Histone Demethylase KDM5C, 李枫 等., 2018
- Regulation of Mismatch Repair by Histone Code and Posttranslational Modifications in Eukaryotic Cells, 李枫 等., 2016
- The histone mark H3K36me3 regulate human mismatch repair through its interaction with MutSalpha, 李枫 等., 2013
