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Lian Duan
Medical School
Wuhan University
Hubei
Language: Chinese, English
Enzymes
Protein Structure
Molecular Interactions
Biosynthetic Pathways
Natural Products
Drug Discovery
Catalytic Functions
Enzyme Engineering
Substrate Specificity
Mechanistic Studies
Areas of Focus
- Enzymatic Mechanisms
- Structural Biology
- Natural Drug Biosynthesis
Work Experience
- 2018 - Present Wuhan University, Associate Research Fellow
- 2012-2017 Brown University, USA, Postdoctoral Research Fellow
- 2011-2012 Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Assistant Researcher
Academic Background & Achievements
- 2006-2011 PhD in Organic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 2002-2006 Bachelor's Degree in Chemistry, Wuhan University
Publications
- The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism, Lian Duan, Gerwald Jogl and David E. Cane, 2016
- Insights into Quinaldic Acid Moiety Formation in Thiostrepton Biosynthesis Facilitating Fluorinated Thiopeptide Generation, Lian Duan, Shoufeng Wang, Rijing Liao and Wen Liu, 2012
- Thiopeptide Biosynthesis Featuring Ribosomally Synthesized Precursor Peptides and Conserved Posttranslational Modifications, R. Liao, L. Duan, C. Lei, H. Pan, Y. Ding, Q. Zhang, D. Chen, B. Shen, Y. Yu and W. Liu, 2009
