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Hu Zheng
Medical School
Wuhan University
Hubei
Language: Chinese, English
Hpv
Cervical Cancer
Genome Integration
Pathophysiology
Molecular Editing
Crispr
Oncogenes
Cancer Therapy
Gene Targeting
Precision Medicine
Areas of Focus
- HPV integration in cervical cancer
- Mechanisms of HPV integration and pathophysiology in cervical cancer
- Design of molecular editing techniques targeting HPV oncogenes
Work Experience
- 2022-12 to present - Vice President, Professor, Chief Physician at Central South Hospital of Wuhan University
- 2016-04 to 2022-12 - Researcher at the First Affiliated Hospital of Sun Yat-sen University
- 2013-12 to 2016-04 - Attending Physician at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
- 2012-07 to 2013-12 - Resident Physician at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Academic Background & Achievements
- 2009-09 to 2012-06 - PhD in Gynecology, Huazhong University of Science and Technology
- 2006-09 to 2009-06 - Master's in Urology, Huazhong University of Science and Technology
- 2001-09 to 2006-06 - Bachelor in Clinical Medicine, Huazhong University of Science and Technology
Publications
- Massively parallel CRISPR off-target detection enables rapid off-target prediction model building, Hu, Z.*, 2023
- HPV integration generates a cellular super-enhancer which functions as ecDNA to regulate genome-wide transcription, Hu, Z.*, 2023
- FrCas9 is a CRISPR/Cas9 system with high editing efficiency and fidelity, Hu, Z.*, 2022
- A Fifteen-Gene Classifier to Predict Neoadjuvant Chemotherapy Responses in Patients with Stage IB to IIB Squamous Cervical Cancer, Hu, Z.*, 2021
- Hyperbranched poly(β-amino ester) based polyplex nanoparticles for delivery of CRISPR/Cas9 system and treatment of HPV infection associated cervical cancer, Hu, Z.*, 2020
Awards
- 2019 - First Prize, National Maternal and Child Health Science and Technology Award
- 2020 - First Prize, Chinese Medical Science and Technology Award
- 2020 - Second Prize, Guangdong University Achievement Roadshow Competition
- 2020 - Excellence Award, First China Health and Longevity Innovation Competition
