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Guohua Ding
Medical School
Wuhan University
Hubei
Language: English, Chinese
Podocyte
Glomerular Sclerosis
Pathobiology
Diabetic Nephropathy
Molecular Mechanism
Nephro-Immunology
Interstitial Inflammation
Kidney Disease
Cell Signaling
Molecular Biology
Areas of Focus
- Pathobiology of glomerular podocyte and glomerular sclerosis
- Molecular mechanism of diabetic nephropathy
- Nephro-immunology and interstitial inflammation
Work Experience
- 1974.07-1984.09 Resident Physician, Renmin Hospital, Wuhan University
- 1993.07-1997.06 Assistant Professor, Pennsylvania State University Medical School, USA
- 1997.07-2001.06 Deputy Director of Nephrology and Internal Medicine
- 2001.07-2018.06 Director of Nephrology and Deputy Director of Internal Medicine
- 1997.07-present Professor of Internal Medicine, Renmin Hospital, Wuhan University
- 2001.07-present Director, Institute of Urinary System Diseases, Wuhan University
Academic Background & Achievements
- 1971.02-1974.07 Bachelor: Wuhan University Medical College
- 1984.09-1990.12 Master and PhD: Albert Einstein College of Medicine, USA
- 1991.09-1993.06 Postdoctoral Research: Pennsylvania State University Medical School, USA
- Published over 500 papers, including more than 100 SCI-indexed articles
Publications
- Reduction of anaerobic glycolysis contributes to angiotensin II-induced podocyte injury with foot process effacement, Chen Z, Zhu Z, Liang W, Ding G, 2023
- PFKFB3 downregulation aggravates Angiotensin II-induced podocyte detachment, Huang X, Chen Z, Ding G, 2023
- STING deletion alleviates podocyte injury through suppressing inflammation by targeting NLRP3 in diabetic kidney disease, Yang X, Chen Z, Ding G, 2023
- AKAP1 contributes to impaired mtDNA replication and mitochondrial dysfunction in podocytes of diabetic kidney disease, Feng J, Chen Z, Ding G, 2022
- Angiotensin II induces podocyte metabolic reprogramming from glycolysis to glycerol-3-phosphate biosynthesis, Luo Z, Chen Z, Ding G, 2022
- Sirt6 deficiency contributes to mitochondrial fission and oxidative damage in podocytes via ROCK1-Drp1 signalling pathway, Chen Z, Liang W, Ding G, 2022
- Roles of Mitochondrial DNA Damage in Kidney Diseases: A New Biomarker, Feng J, Chen Z, Ding G, 2022
- Mfn2 Regulates High Glucose-Induced MAMs Dysfunction and Apoptosis in Podocytes via PERK Pathway, Cao Y, Chen Z, Ding G, 2021
- PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease, Zhang Z, Liang W, Ding G, 2022
- Roles of SIRT6 in kidney disease: a novel therapeutic target, Yang X, Feng J, Ding G, 2021
Awards
- 2002 Hubei Province Natural Science Second Prize
- 2004 Hubei Province Science and Technology Progress Third Prize
- 2006 Hubei Province Science and Technology Progress Second Prize
- 2011 Hubei Province Science and Technology Progress First Prize
- 2019 Hubei Province Science and Technology Progress Second Prize
