Professor | Chen She | Asia Growth Partners

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Name	Chen She
Contact Information	shechen@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Chen She

Contact Information

shechen@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1993.09—1998.06 Bachelor in Clinical Medicine: Shanghai Medical University 1998.09—2003.06 PhD in Biochemistry and Molecular Biology: Fudan University Shanghai Medical College
Work Experience	2003.08—2006.07 - New York State Institute for Basic Research - Research Scientist 2006.07—2013.01 - Memorial Sloan Kettering Cancer Center - Research Associate 2013.06—Present - Fudan University - Researcher 2019.11—2020.11 - Chongming District Medical Insurance Bureau, Shanghai - Deputy Director
Awards	2018: Fudan University March 8th Red Banner Holder 2006: Fellowship at the 10th International Conference on Alzheimer's Disease and Related Disorders 2003: Second Prize of Shanghai Science and Technology Progress Award (Third Contributor) 2002: Second Prize of Shanghai Medical Science and Technology Award (Fourth Contributor)

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1993.09—1998.06 Bachelor in Clinical Medicine: Shanghai Medical University
1998.09—2003.06 PhD in Biochemistry and Molecular Biology: Fudan University Shanghai Medical College

Work Experience

2003.08—2006.07 - New York State Institute for Basic Research - Research Scientist
2006.07—2013.01 - Memorial Sloan Kettering Cancer Center - Research Associate
2013.06—Present - Fudan University - Researcher
2019.11—2020.11 - Chongming District Medical Insurance Bureau, Shanghai - Deputy Director

Awards

2018: Fudan University March 8th Red Banner Holder
2006: Fellowship at the 10th International Conference on Alzheimer's Disease and Related Disorders
2003: Second Prize of Shanghai Science and Technology Progress Award (Third Contributor)
2002: Second Prize of Shanghai Medical Science and Technology Award (Fourth Contributor)

Areas of Focus	Tumorigenesis and Microenvironment Environment and Health
Publications	A plasma SNORD33 signature predicts platinum benefit in metastatic triple-negative breast cancer patients, Wang, B., Zhao, Y., Li, Y., Xu, Y., Chen, Y., Jiang, Q., Yao, D., Zhang, L., Hu, X., Fu, C., Zhang, S., and Chen, S., 2022 Hepatic NOD2 promotes hepatocarcinogenesis via a RIP2-mediated proinflammatory response and a novel nuclear autophagy-mediated DNA damage mechanism, Zhou, Y., Hu, L., Tang, W., Li, D., Ma, L., Liu, H., Zhang, S., Zhang, X., Dong, L., Shen, X., Chen, S., Xue, R., and Zhang, S., 2021 MRCKbeta links Dasm1 to actin rearrangements to promote dendrite development, Wang, X. X., Zhang, S., Dong, P. P., Li, Y. H., Zhang, L., Shi, S. H., Yu, Z. Q., and Chen, S., 2021 Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis, Wang, S., Cai, J., Zhang, S., Dong, M., Zhang, L., Xu, Y., Shen, B., and Chen, S., 2021 Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma, Dong, P., Wang, X., Liu, L., Tang, W., Ma, L., Zeng, W., Sun, S., Zhang, L., Zhang, N., Shen, X., Janssen, H. L. A., Dong, L., Zhang, S., and Chen, S., 2020 CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation, Zhao, G. X., Xu, Y. Y., Weng, S. Q., Zhang, S., Chen, Y., Shen, X. Z., Dong, L., and Chen, S., 2019 PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia, Liu, W. A., Chen, S., Li, Z., Lee, C. H., Mirzaa, G., Dobyns, W. B., Ross, M. E., Zhang, J., and Shi, S. H., 2018 Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity, Chen, S., Chen, J., Shi, H., Wei, M., Castaneda-Castellanos, D. R., Bultje, R. S., Pei, X., Kriegstein, A. R., Zhang, M., and Shi, S. H., 2013 Clonal production and organization of inhibitory interneurons in the neocortex, Brown, K. N., Chen, S., Han, Z., Lu, C. H., Tan, X., Zhang, X. J., Ding, L., Lopez-Cruz, A., Saur, D., Anderson, S. A., Huang, K., and Shi, S. H., 2011 I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A, Chen, S., Li, B., Grundke-Iqbal, I., and Iqbal, K., 2008

Areas of Focus

Tumorigenesis and Microenvironment
Environment and Health

Publications

A plasma SNORD33 signature predicts platinum benefit in metastatic triple-negative breast cancer patients, Wang, B., Zhao, Y., Li, Y., Xu, Y., Chen, Y., Jiang, Q., Yao, D., Zhang, L., Hu, X., Fu, C., Zhang, S., and Chen, S., 2022
Hepatic NOD2 promotes hepatocarcinogenesis via a RIP2-mediated proinflammatory response and a novel nuclear autophagy-mediated DNA damage mechanism, Zhou, Y., Hu, L., Tang, W., Li, D., Ma, L., Liu, H., Zhang, S., Zhang, X., Dong, L., Shen, X., Chen, S., Xue, R., and Zhang, S., 2021
MRCKbeta links Dasm1 to actin rearrangements to promote dendrite development, Wang, X. X., Zhang, S., Dong, P. P., Li, Y. H., Zhang, L., Shi, S. H., Yu, Z. Q., and Chen, S., 2021
Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis, Wang, S., Cai, J., Zhang, S., Dong, M., Zhang, L., Xu, Y., Shen, B., and Chen, S., 2021
Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma, Dong, P., Wang, X., Liu, L., Tang, W., Ma, L., Zeng, W., Sun, S., Zhang, L., Zhang, N., Shen, X., Janssen, H. L. A., Dong, L., Zhang, S., and Chen, S., 2020
CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation, Zhao, G. X., Xu, Y. Y., Weng, S. Q., Zhang, S., Chen, Y., Shen, X. Z., Dong, L., and Chen, S., 2019
PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia, Liu, W. A., Chen, S., Li, Z., Lee, C. H., Mirzaa, G., Dobyns, W. B., Ross, M. E., Zhang, J., and Shi, S. H., 2018
Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity, Chen, S., Chen, J., Shi, H., Wei, M., Castaneda-Castellanos, D. R., Bultje, R. S., Pei, X., Kriegstein, A. R., Zhang, M., and Shi, S. H., 2013
Clonal production and organization of inhibitory interneurons in the neocortex, Brown, K. N., Chen, S., Han, Z., Lu, C. H., Tan, X., Zhang, X. J., Ding, L., Lopez-Cruz, A., Saur, D., Anderson, S. A., Huang, K., and Shi, S. H., 2011
I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A, Chen, S., Li, B., Grundke-Iqbal, I., and Iqbal, K., 2008

Tumorigenesis Microenvironment Cancer Metastasis Molecular Mechanisms Health Environment Biochemistry Cell Biology Research

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