Professor | 陈舌 | 数字化转型顾问

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Name	陈舌
Contact Information	shechen@fudan.edu.cn
Language ability	中文, 英文
Province	上海

Upload Avatar (500 x 500)

Name

陈舌

Contact Information

shechen@fudan.edu.cn

Language ability

中文, 英文

Province

上海

University/Lab Affiliation and Title	复旦大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	1993.09—1998.06 临床医学学士: 上海医科大学 1998.09—2003.06 生物化学与分子生物学博士: 复旦大学上海医学院
Work Experience	2003.08—2006.07 - 美国纽约州立基础研究所 - 研究科学家 2006.07—2013.01 - 美国纽约斯隆凯特琳癌症中心 - 研究助理 2013.06—至今 - 复旦大学 - 研究员 2019.11—2020.11 - 上海市崇明区医疗保障局 - 副局长
Awards	2018: 复旦大学三八红旗手 2006: 第十届国际Alzheimer’s Disease及其相关疾病大会Fellowship 2003: 上海市科学技术进步奖二等奖（第三完成者） 2002: 上海市医学科技奖二等奖（第四完成者）

University/Lab Affiliation and Title

复旦大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

1993.09—1998.06 临床医学学士: 上海医科大学
1998.09—2003.06 生物化学与分子生物学博士: 复旦大学上海医学院

Work Experience

2003.08—2006.07 - 美国纽约州立基础研究所 - 研究科学家
2006.07—2013.01 - 美国纽约斯隆凯特琳癌症中心 - 研究助理
2013.06—至今 - 复旦大学 - 研究员
2019.11—2020.11 - 上海市崇明区医疗保障局 - 副局长

Awards

2018: 复旦大学三八红旗手
2006: 第十届国际Alzheimer’s Disease及其相关疾病大会Fellowship
2003: 上海市科学技术进步奖二等奖（第三完成者）
2002: 上海市医学科技奖二等奖（第四完成者）

Areas of Focus	肿瘤发生与微环境环境与健康
Publications	A plasma SNORD33 signature predicts platinum benefit in metastatic triple-negative breast cancer patients, Wang, B., Zhao, Y., Li, Y., Xu, Y., Chen, Y., Jiang, Q., Yao, D., Zhang, L., Hu, X., Fu, C., Zhang, S., and Chen, S., 2022 Hepatic NOD2 promotes hepatocarcinogenesis via a RIP2-mediated proinflammatory response and a novel nuclear autophagy-mediated DNA damage mechanism, Zhou, Y., Hu, L., Tang, W., Li, D., Ma, L., Liu, H., Zhang, S., Zhang, X., Dong, L., Shen, X., Chen, S., Xue, R., and Zhang, S., 2021 MRCKbeta links Dasm1 to actin rearrangements to promote dendrite development, Wang, X. X., Zhang, S., Dong, P. P., Li, Y. H., Zhang, L., Shi, S. H., Yu, Z. Q., and Chen, S., 2021 Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis, Wang, S., Cai, J., Zhang, S., Dong, M., Zhang, L., Xu, Y., Shen, B., and Chen, S., 2021 Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma, Dong, P., Wang, X., Liu, L., Tang, W., Ma, L., Zeng, W., Sun, S., Zhang, L., Zhang, N., Shen, X., Janssen, H. L. A., Dong, L., Zhang, S., and Chen, S., 2020 CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation, Zhao, G. X., Xu, Y. Y., Weng, S. Q., Zhang, S., Chen, Y., Shen, X. Z., Dong, L., and Chen, S., 2019 PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia, Liu, W. A., Chen, S., Li, Z., Lee, C. H., Mirzaa, G., Dobyns, W. B., Ross, M. E., Zhang, J., and Shi, S. H., 2018 Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity, Chen, S., Chen, J., Shi, H., Wei, M., Castaneda-Castellanos, D. R., Bultje, R. S., Pei, X., Kriegstein, A. R., Zhang, M., and Shi, S. H., 2013 Clonal production and organization of inhibitory interneurons in the neocortex, Brown, K. N., Chen, S., Han, Z., Lu, C. H., Tan, X., Zhang, X. J., Ding, L., Lopez-Cruz, A., Saur, D., Anderson, S. A., Huang, K., and Shi, S. H., 2011 I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A, Chen, S., Li, B., Grundke-Iqbal, I., and Iqbal, K., 2008

Areas of Focus

肿瘤发生与微环境
环境与健康

Publications

A plasma SNORD33 signature predicts platinum benefit in metastatic triple-negative breast cancer patients, Wang, B., Zhao, Y., Li, Y., Xu, Y., Chen, Y., Jiang, Q., Yao, D., Zhang, L., Hu, X., Fu, C., Zhang, S., and Chen, S., 2022
Hepatic NOD2 promotes hepatocarcinogenesis via a RIP2-mediated proinflammatory response and a novel nuclear autophagy-mediated DNA damage mechanism, Zhou, Y., Hu, L., Tang, W., Li, D., Ma, L., Liu, H., Zhang, S., Zhang, X., Dong, L., Shen, X., Chen, S., Xue, R., and Zhang, S., 2021
MRCKbeta links Dasm1 to actin rearrangements to promote dendrite development, Wang, X. X., Zhang, S., Dong, P. P., Li, Y. H., Zhang, L., Shi, S. H., Yu, Z. Q., and Chen, S., 2021
Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis, Wang, S., Cai, J., Zhang, S., Dong, M., Zhang, L., Xu, Y., Shen, B., and Chen, S., 2021
Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1/TSC2 association in hepatocellular carcinoma, Dong, P., Wang, X., Liu, L., Tang, W., Ma, L., Zeng, W., Sun, S., Zhang, L., Zhang, N., Shen, X., Janssen, H. L. A., Dong, L., Zhang, S., and Chen, S., 2020
CAPS1 promotes colorectal cancer metastasis via Snail mediated epithelial mesenchymal transformation, Zhao, G. X., Xu, Y. Y., Weng, S. Q., Zhang, S., Chen, Y., Shen, X. Z., Dong, L., and Chen, S., 2019
PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia, Liu, W. A., Chen, S., Li, Z., Lee, C. H., Mirzaa, G., Dobyns, W. B., Ross, M. E., Zhang, J., and Shi, S. H., 2018
Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity, Chen, S., Chen, J., Shi, H., Wei, M., Castaneda-Castellanos, D. R., Bultje, R. S., Pei, X., Kriegstein, A. R., Zhang, M., and Shi, S. H., 2013
Clonal production and organization of inhibitory interneurons in the neocortex, Brown, K. N., Chen, S., Han, Z., Lu, C. H., Tan, X., Zhang, X. J., Ding, L., Lopez-Cruz, A., Saur, D., Anderson, S. A., Huang, K., and Shi, S. H., 2011
I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A, Chen, S., Li, B., Grundke-Iqbal, I., and Iqbal, K., 2008

肿瘤发生微环境癌症转移分子机制健康环境生物化学细胞生物学研究

徐国恒 - 北京大学

张炜真 - 北京大学

孔炜 - 北京大学

Area of Focus
血管 | 微环境 | 心血管 | 疾病 | 病理生理学 | 研究 | 生物学 | 临床 | 治疗 | 预防

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