Areas of Focus
- Antiviral Immunity
- Tumor Immunity
- Viral Infection
- Cell Damage
- Autoimmune Diseases
Work Experience
- 2019-present - Editorial Board Member - Frontiers in Immunology
Academic Background & Achievements
- Research on antiviral innate immunity and autoimmune diseases
- Published in Cell, Nature Immunology, Molecular Cell, and Nature Communications
- Research selected as one of China's Top 10 Scientific Advances in 2019
- Recipient of the National Science Fund for Distinguished Young Scholars
- Selected for the National Hundred, Thousand, and Ten Thousand Talent Project
- Recipient of the Tan Jiazhen Life Science Innovation Award
Publications
- GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein, Zhao M, Yu Y, Sun LM, Xing JQ, Li T, Zhu Y, Wang M, Yu Y, Xue W, Xia T, Cai H, Han QY, Yin X, Li WH, Li AL, Cui J, Yuan Z, Zhang R, Zhou T, Zhang XM, Li T*, 2021
- Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity, Dai J, Huang YJ, He X, Zhao M, Wang X, Liu ZS, Xue W, Cai H, Zhan XY, Huang SY, He K, Wang H, Wang N, Sang Z, Li T, Han QY, Mao J, Diao X, Song N, Chen Y, Li WH, Man JH, Li AL, Zhou T, Liu ZG, Zhang XM, Li T*, 2019
- G3BP1 promotes DNA binding and activation of cGAS, Liu ZS, Cai H, Xue W, Wang M, Xia T, Li WJ, Xing JQ, Zhao M, Huang YJ, Chen S, Wu SM, Wang X, Liu X, Pang X, Zhang ZY, Li T, Dai J, Dong F, Xia Q, Li AL, Zhou T, Liu ZG, Zhang XM, Li T*, 2019
- NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation, Song N, Liu ZS, Xue W, Bai ZF, Wang QY, Dai J, Liu X, Huang YJ, Cai H, Zhan XY, Han QY, Wang H, Chen Y, Li HY, Li AL, Zhang XM, Zhou T, Li T*, 2017
- Regulation of NLRP3 Inflammasome by Phosphorylation, Song N, Li T*, 2018
- RINCK-mediated monoubiquitination of cGAS promotes antiviral innate immune responses, Liu ZS, Zhang ZY, Cai H, Zhao M, Mao J, Dai J, Xia T, Zhang XM, Li T*, 2018
Awards
- National Science Fund for Distinguished Young Scholars (2019)
- National Hundred, Thousand, and Ten Thousand Talent Project (2019)
- Tan Jiazhen Life Science Innovation Award (2019)
- National Innovation Talent Promotion Plan - Young and Middle-aged Science and Technology Innovation Leading Talent (2018)
