Upload Avatar (500 x 500)
Dongyun Shi
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Metabolic Regulation
Targeted Intervention
Stress Microenvironment
Tumors
Diabetes
Hypoxia Protection
Redox Balance
Major Diseases
Precise Intervention
Scientific Definition
Areas of Focus
- Research on metabolic regulation and targeted intervention in the stress microenvironment of tumors and diabetes
- Research on hypoxia protection mechanisms and interventions
- Scientific definition and precise intervention strategies for redox balance in major diseases
Work Experience
- 2009-present - Fudan University, School of Basic Medical Sciences - Associate Professor, Professor
- 1997-2003 - Fudan University, Shanghai Medical College - Lecturer
- 1991-1996 - Shanghai Second Medical University, School of Basic Medical Sciences - Assistant Lecturer, Lecturer
Academic Background & Achievements
- 1987.9-1991.7 Bachelor's in Chemistry: Fudan University
- 1998.9-2002.7 Master's in Biochemistry and Molecular Biology: Fudan University
- 2003.9-2007.7 PhD: King's College, University of London
Publications
- Compartmentally scavenging hepatic oxidants through AMPK/ SIRT3-PGC1α axis improves mitochondrial biogenesis and glucose catabolism, Meiling Wu, Chunwang Zhang, Mengdan Xie, Yuansheng Zhen, Ben Lai, Jiankang Liu, Liang Qiao, Shanlin Liu, Dongyun Shi, 2021
- Liver-targeted Nano-MitoPBN normalizes glucose metabolism through improving mitochondrial redox balance, Meiling Wu, Lihao Liao, Lihan Jiang, Chunwang Zhang, Hongyang Gao, Liang Qiao, Shanlin Liu, Dongyun Shi, 2019
- NAC selectively inhibit cancer telomerase activity: A higher redox homeostasis threshold exists in cancer cells, Pengying Li, Meilin Wu, Jing Wang, Yilun Sui, Shanlin Liu, Dongyun Shi, 2016
- Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes, Kelei Dong, Meiling Wu, Xiaomin Liu, Dongyang Zhang, Yanjie Huang, Yiting Wang, Liang-Jun Yan, Dongyun Shi, 2016
- Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells, Li P, Zhang D, Shen L, Dong K, Wu M, Ou Z, Shi D, 2016
Awards
- 2010: Second Prize in Natural Science by the Ministry of Education
- 2019: Excellent Mentor Award by Shanghai Municipal Education Commission
- 2020: Excellence Award in the Outstanding Reward Program by Fudan University, School of Basic Medical Sciences
