Professor | Weili Zhao | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Weili Zhao
Contact Information	zhaoweili@fudan.edu.cn
Language ability	English, Chinese, German
Province	Shanghai

Upload Avatar (500 x 500)

Name

Weili Zhao

Contact Information

zhaoweili@fudan.edu.cn

Language ability

English, Chinese, German

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	1998.10-2002.10 Postdoctoral: Swiss Federal Institute of Technology Zurich 1998.07-1998.10 Postdoctoral: California Institute of Technology 1997.07-1998.07 Visiting Scholar: University of California, Irvine 1994.07-1997.07 Ph.D.: Institute of Photographic Chemistry, Chinese Academy of Sciences 1987.07-1990.07 M.Sc.: Institute of Photographic Chemistry, Chinese Academy of Sciences 1983.07-1987.07 B.Sc.: Department of Chemistry, Wuhan University
Work Experience	2009.04-Present - Fudan University - Researcher, Doctoral Supervisor 2005.11-2009.03 - Roche R&D (China) Co., Ltd. - Deputy Director, Director of Drug Development 2002.10-2005.11 - Swiss Federal Institute of Technology Zurich - 'Wissenschaftlicher Mitarbeiter' 1990.07-1994.07 - Henan University - Assistant Lecturer, Lecturer

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

1998.10-2002.10 Postdoctoral: Swiss Federal Institute of Technology Zurich
1998.07-1998.10 Postdoctoral: California Institute of Technology
1997.07-1998.07 Visiting Scholar: University of California, Irvine
1994.07-1997.07 Ph.D.: Institute of Photographic Chemistry, Chinese Academy of Sciences
1987.07-1990.07 M.Sc.: Institute of Photographic Chemistry, Chinese Academy of Sciences
1983.07-1987.07 B.Sc.: Department of Chemistry, Wuhan University

Work Experience

2009.04-Present - Fudan University - Researcher, Doctoral Supervisor
2005.11-2009.03 - Roche R&D (China) Co., Ltd. - Deputy Director, Director of Drug Development
2002.10-2005.11 - Swiss Federal Institute of Technology Zurich - 'Wissenschaftlicher Mitarbeiter'
1990.07-1994.07 - Henan University - Assistant Lecturer, Lecturer

Areas of Focus	Research on anti-tumor small molecule targeted drugs Organic synthesis methods Fluorescent probes and sensors
Publications	Discovery of an Amino Acid-Modified Near-Infrared Aza-BODIPY Photosensitizer as an Immune Initiator for Potent Photodynamic Therapy in Melanoma, Zhiliang Yu, Hong Wang, Zhongjian Chen, Xiaochun Dong, Weili Zhao, Yuling Shi, Quangang Zhu, 2022 Development of environment-insensitive and highly emissive BODIPYs via installation of N, N’-dialkylsubstituted amide at meso position, Junping Bai, Junliang Zhou, Xin Ji, Nannan Wang, Xiaochun Dong, Wei Wu, Weili Zhao, 2022 Near-infrared fluorophores with absolute aggregation-caused quenching and negligible fluorescence re-illumination for in vivo bioimaging of nanocarriers, Yifan Cai, Xin Ji, Yunsen Zhang, Chang Liu, Zichen Zhang, Yongjiu Lv, Xiaochun Dong, Haisheng He, Jianping Qi, Yi Lu, Defang Ouyang, Weili Zhao, Wei Wu, 2022 Accurate and sensitive probing of onset of micellization based on absolute aggregation-caused quenching effect, Haisheng He, Chang Liu, Jiang Ming, Yongjiu Lv, Jianping Qi, Yi Lu, Xiaochun Dong, Weili Zhao, Wei Wu, 2022 Discovery of meso-(meta-pyridinium) BODIPY photosensitizers: In vitro and in vivo evaluations for antimicrobial photodynamic therapy, Guangyu Lin, Mei Hu, Rong Zhang, Yuanxing Zhu, Kedan Gu, Junping Bai, Jiyang Li, Xiaochun Dong,Weili Zhao, 2021 Discovery of a Monoiodo Aza-BODIPY Near-Infrared Photosensitizer: in vitro and in vivo Evaluation for Photodynamic Therapy, Zhiliang Yu, Junliang Zhou, Xin Ji, Guangyu Lin, Shuang Xu, Xiaochun Dong, Weili Zhao, 2020 Anchoring BODIPY photosensitizers enable pan-microbial photoinactivation, Kedan Gu, Guangyu Lin, Yuanxing Zhu, Xin Ji, Jiyang Li, Xiaochun Dong, Weili Zhao, 2020 Azetidine-Containing Heterospirocycles Enhance the Performance of Fluorophores, Junliang Zhou, Xianfeng Lin, Xin Ji, Shuang Xu, Chang Liu, Xiaochun Dong, Weili Zhao, 2020 Response to Comment on “Water-Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability Superoxide Detection in Live Cells and in Zebrafish Embryos”, Xiuhong Lu, Guangyu Lin, Xiaochun Dong, Weili Zhao, Zhongjian Chen, 2019 Fluorescent probe for sensitive discrimination of Hcy and Cys/GSH in living cells via dual-emission, Shuang Xu, Junliang Zhou, Xiaochun Dong, Weili Zhao, Quangang Zhu, 2019 Visualizing Nitric Oxide in Mitochondria and Lysosomes of Living Cells with N-Nitrosation of BODIPY-based Fluorescent Probes, Zhiliang Yu, Junliang Zhou, Xiaochun Dong, Weili Zhao, Zhongjian Chen, 2019 Pyridinium substituted BODIPY as NIR fluorescent probe for simultaneous sensing of hydrogen sulphide/glutathione and cysteine/homocysteine, Jian Zhang, Xin Ji, Junliang Zhou, Zhongjian Chen, Xiaochun Dong, Weili Zhao, 2018 Water-Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability for Selective Superoxide Detection in Live Cells and in Zebrafish Embryos, Xiuhong Lu, Zhongjian Chen, Xiaochun Dong, Weili Zhao, 2018 Overcoming the resistance mechanisms of Smoothened inhibitors, Xiaochun Dong, Chenglin Wang, Zhongjian Chen, Weili Zhao, 2018 A mitochondria-targeted turn-on fuorescent probe for the detection of glutathione in living cells, Jian Zhang, Xiaolong Bao, Junliang Zhou, Fangfang Peng, Hang Ren, Xiaochun Dong, Weili Zhao, 2016 A multi-functional probe to discriminate Lys, Arg, His, Cys, Hcy and GSH from common amino acids, Xiuhong Lu, Wen Wang, Qian Dong, Xiaolong Bao, Xianfeng Lin, Weixing Zhang, Xiaochun Dong, Weili Zhao, 2015

Areas of Focus

Research on anti-tumor small molecule targeted drugs
Organic synthesis methods
Fluorescent probes and sensors

Publications

Discovery of an Amino Acid-Modified Near-Infrared Aza-BODIPY Photosensitizer as an Immune Initiator for Potent Photodynamic Therapy in Melanoma, Zhiliang Yu, Hong Wang, Zhongjian Chen, Xiaochun Dong, Weili Zhao*, Yuling Shi*, Quangang Zhu*, 2022
Development of environment-insensitive and highly emissive BODIPYs via installation of N, N’-dialkylsubstituted amide at meso position, Junping Bai, Junliang Zhou, Xin Ji, Nannan Wang, Xiaochun Dong*, Wei Wu*, Weili Zhao*, 2022
Near-infrared fluorophores with absolute aggregation-caused quenching and negligible fluorescence re-illumination for in vivo bioimaging of nanocarriers, Yifan Cai, Xin Ji, Yunsen Zhang, Chang Liu, Zichen Zhang, Yongjiu Lv, Xiaochun Dong, Haisheng He, Jianping Qi, Yi Lu, Defang Ouyang*, Weili Zhao*, Wei Wu*, 2022
Accurate and sensitive probing of onset of micellization based on absolute aggregation-caused quenching effect, Haisheng He, Chang Liu, Jiang Ming, Yongjiu Lv, Jianping Qi, Yi Lu, Xiaochun Dong, Weili Zhao*, Wei Wu*, 2022
Discovery of meso-(meta-pyridinium) BODIPY photosensitizers: In vitro and in vivo evaluations for antimicrobial photodynamic therapy, Guangyu Lin, Mei Hu, Rong Zhang, Yuanxing Zhu, Kedan Gu, Junping Bai, Jiyang Li*, Xiaochun Dong*,Weili Zhao*, 2021
Discovery of a Monoiodo Aza-BODIPY Near-Infrared Photosensitizer: in vitro and in vivo Evaluation for Photodynamic Therapy, Zhiliang Yu, Junliang Zhou, Xin Ji, Guangyu Lin, Shuang Xu, Xiaochun Dong*, Weili Zhao*, 2020
Anchoring BODIPY photosensitizers enable pan-microbial photoinactivation, Kedan Gu, Guangyu Lin, Yuanxing Zhu, Xin Ji, Jiyang Li*, Xiaochun Dong*, Weili Zhao*, 2020
Azetidine-Containing Heterospirocycles Enhance the Performance of Fluorophores, Junliang Zhou, Xianfeng Lin, Xin Ji, Shuang Xu, Chang Liu, Xiaochun Dong*, Weili Zhao*, 2020
Response to Comment on “Water-Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability Superoxide Detection in Live Cells and in Zebrafish Embryos”, Xiuhong Lu, Guangyu Lin, Xiaochun Dong*, Weili Zhao*, Zhongjian Chen*, 2019
Fluorescent probe for sensitive discrimination of Hcy and Cys/GSH in living cells via dual-emission, Shuang Xu, Junliang Zhou, Xiaochun Dong*, Weili Zhao*, Quangang Zhu*, 2019
Visualizing Nitric Oxide in Mitochondria and Lysosomes of Living Cells with N-Nitrosation of BODIPY-based Fluorescent Probes, Zhiliang Yu, Junliang Zhou, Xiaochun Dong*, Weili Zhao*, Zhongjian Chen*, 2019
Pyridinium substituted BODIPY as NIR fluorescent probe for simultaneous sensing of hydrogen sulphide/glutathione and cysteine/homocysteine, Jian Zhang, Xin Ji, Junliang Zhou, Zhongjian Chen*, Xiaochun Dong*, Weili Zhao*, 2018
Water-Soluble Fluorescent Probe with Dual Mitochondria/Lysosome Targetability for Selective Superoxide Detection in Live Cells and in Zebrafish Embryos, Xiuhong Lu, Zhongjian Chen*, Xiaochun Dong*, Weili Zhao*, 2018
Overcoming the resistance mechanisms of Smoothened inhibitors, Xiaochun Dong, Chenglin Wang, Zhongjian Chen*, Weili Zhao*, 2018
A mitochondria-targeted turn-on fuorescent probe for the detection of glutathione in living cells, Jian Zhang, Xiaolong Bao, Junliang Zhou, Fangfang Peng, Hang Ren, Xiaochun Dong*, Weili Zhao*, 2016
A multi-functional probe to discriminate Lys, Arg, His, Cys, Hcy and GSH from common amino acids, Xiuhong Lu, Wen Wang, Qian Dong, Xiaolong Bao, Xianfeng Lin, Weixing Zhang, Xiaochun Dong*, Weili Zhao*, 2015

Anti-Tumor Small Molecule Targeted Drugs Organic Synthesis Fluorescent Probes Sensors Drug Development Photodynamic Therapy Bioimaging Chemical Research

Wenfu Tan - Fudan University

Xiaochun Dong - Fudan University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us