Upload Avatar (500 x 500)
Yu Sun
Pharmaceutical Sciences
Fudan University
Shanghai
Language: Chinese, English
Natural Products
Total Synthesis
Biological Activity
Transition Metals
Stereospecific Reactions
Drug Synthesis
Lead Compounds
Structure-Activity Relationship
Organic Chemistry
Catalysis
Areas of Focus
- Total synthesis of complex natural products with biological activity
- Development of highly stereospecific reactions catalyzed by transition metals and their application in the synthesis of natural products and drugs
- Discovery of lead compounds based on natural products and structure-activity relationship studies
Work Experience
- 2020-present - Fudan University - Junior Researcher
- 2017-2020 - Boston College - Postdoctoral Researcher (Supervisor: Prof. Amir H. Hoveyda)
- 2016-2017 - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2011-2016 PhD: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (Supervisor: Ang Li)
- 2007-2011 Bachelor: School of Pharmacy, Fudan University
- 2016 Reaxys PhD Prize (Finalist)
- 2014 Excellent Award of the President of the Chinese Academy of Sciences
- 2013 Special Symposium Award, Roche and Royal Society of Chemistry Symposium
Publications
- Copper?Hydride-Catalyzed Enantioselective Processes with Allenyl Boronates. Mechanistic Nuances, Scope, and Utility in Target-Oriented Synthesis, Y. Sun, Y. Zhou, Y. Shi, J. del Pozo, S. Torker, and A. H. Hoveyda, 2019
- Bioinspired Total Synthesis of Sespenine, Y. Sun, P. Chen, D. Zhang, M. Baunach, C. Hertweck, and A. Li, 2014
- Total Synthesis of Indotertine A and Drimentines A, F, and G, Y. Sun, R. Li, W. Zhang, and A. Li, 2013
- A concise total synthesis of sespenine, a structurally unusual indole terpenoid from Streptomyces, Y. Sun, Z. Meng, P. Chen, D. Zhang, M. Baunach, C. Hertweck, and A. Li, 2016
- Elucidating the Cyclization Cascades in Xiamycin Biosynthesis by Substrate Synthesis and Enzyme Characterizations, H. Li, Y. Sun, Q. Zhang, Y. Zhu, S. Li, A. Li, and C. Zhang, 2015
- Characterization of the flavoenzyme Xia K as an N-hydroxylase and implications in indolosesquiterpene diversification, Q. Zhang, H. Li, Y. Sun, L. Yu, Y. Zhu, H. Zhu, L. Zhang, S. Li, Y. Shen, C. Tian, A. Li, H. Liu and C. Zhang, 2017
- Identification and mechanistic studies of a cell cycle regulator JP18 from a library of synthetic indole terpenoid mimics, J. Pei, S. Zhou, F. Yang, Y. Sun, A. Li, W. Zhang, and W. He, 2016
- Synthesis of Indole Terpenoid Mimics via a Functionality-Tolerated Eu(fod)3-Catalyzed Conjugate Addition, X. Xiong, D. Zhang, J. Li, Y. Sun, S. Zhou, M. Yang, H. Shao, and A. Li, 2015
- Intermolecular Conjugate Addition of Pyrroloindoline and Furoindoline Radicals to α,β-Unsaturated Enones via Photoredox Catalysis, S. Zhou, D. Zhang, Y. Sun, R. Li, W. Zhang, and A. Li, 2014
- Total Syntheses of Anominine and Tubingensin A, M. Bian, Z. Wang, X. C. Xiong, Y. Sun, C. Matera, K. C. Nicolaou, and A. Li, 2012
Awards
- Reaxys PhD Prize (2016): Finalist
- Excellent Award of the President of the Chinese Academy of Sciences (2014)
- Special Symposium Award, Roche and Royal Society of Chemistry Symposium (2013)
