Upload Avatar (500 x 500)
孙域
Pharmaceutical Sciences
复旦大学
上海
Language: 中文, 英语
天然产物
全合成
生物活性
过渡金属
立体专一性反应
药物合成
先导化合物
构效关系
有机化学
催化
Areas of Focus
- 具有生物活性的复杂天然产物的全合成
- 过渡金属催化的高立体专一性反应的开发及其在天然产物、药物合成中的应用
- 基于天然产物的先导化合物发现及构效关系研究
Work Experience
- 2020-至今 - 复旦大学 - 青年研究员
- 2017-2020 - 波士顿学院 - 博士后 (导师: Prof. Amir H. Hoveyda)
- 2016-2017 - 中国科学院上海有机化学研究所 - 助理研究员
Academic Background & Achievements
- 2011-2016 博士: 中国科学院上海有机化学研究所 (导师: 李昂)
- 2007-2011 学士: 复旦大学药学院
- 2016 Reaxys PhD Prize（入围奖）
- 2014 中国科学院院长优秀奖
- 2013 Special Symposium Award, Roche and Royal Society of Chemistry Symposium
Publications
- Copper?Hydride-Catalyzed Enantioselective Processes with Allenyl Boronates. Mechanistic Nuances, Scope, and Utility in Target-Oriented Synthesis, Y. Sun, Y. Zhou, Y. Shi, J. del Pozo, S. Torker, and A. H. Hoveyda, 2019
- Bioinspired Total Synthesis of Sespenine, Y. Sun, P. Chen, D. Zhang, M. Baunach, C. Hertweck, and A. Li, 2014
- Total Synthesis of Indotertine A and Drimentines A, F, and G, Y. Sun, R. Li, W. Zhang, and A. Li, 2013
- A concise total synthesis of sespenine, a structurally unusual indole terpenoid from Streptomyces, Y. Sun, Z. Meng, P. Chen, D. Zhang, M. Baunach, C. Hertweck, and A. Li, 2016
- Elucidating the Cyclization Cascades in Xiamycin Biosynthesis by Substrate Synthesis and Enzyme Characterizations, H. Li, Y. Sun, Q. Zhang, Y. Zhu, S. Li, A. Li, and C. Zhang, 2015
- Characterization of the flavoenzyme Xia K as an N-hydroxylase and implications in indolosesquiterpene diversification, Q. Zhang, H. Li, Y. Sun, L. Yu, Y. Zhu, H. Zhu, L. Zhang, S. Li, Y. Shen, C. Tian, A. Li, H. Liu and C. Zhang, 2017
- Identification and mechanistic studies of a cell cycle regulator JP18 from a library of synthetic indole terpenoid mimics, J. Pei, S. Zhou, F. Yang, Y. Sun, A. Li, W. Zhang, and W. He, 2016
- Synthesis of Indole Terpenoid Mimics via a Functionality-Tolerated Eu(fod)3-Catalyzed Conjugate Addition, X. Xiong, D. Zhang, J. Li, Y. Sun, S. Zhou, M. Yang, H. Shao, and A. Li, 2015
- Intermolecular Conjugate Addition of Pyrroloindoline and Furoindoline Radicals to α,β-Unsaturated Enones via Photoredox Catalysis, S. Zhou, D. Zhang, Y. Sun, R. Li, W. Zhang, and A. Li, 2014
- Total Syntheses of Anominine and Tubingensin A, M. Bian, Z. Wang, X. C. Xiong, Y. Sun, C. Matera, K. C. Nicolaou, and A. Li, 2012
Awards
- Reaxys PhD Prize (2016): 入围奖
- 中国科学院院长优秀奖 (2014)
- Special Symposium Award, Roche and Royal Society of Chemistry Symposium (2013)
