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Jingdong Cheng
Biomedical Sciences
Fudan University
Shanghai
Language: English, Chinese, German
Translational Regulation
Molecular Mechanisms
Structural Biology
Cryo-Em
X-Ray Crystallography
Ribosome Assembly
Ribosome Degradation
Ribosome Modification
Ribosome Quality Control
Nucleic Acid-Protein Complexes
Areas of Focus
- Molecular Mechanisms of Translational Regulation
Work Experience
- 2021.7-present - Fudan University - Young Researcher
- 2015.3-2021.6 - University of Munich - Postdoctoral Researcher
Academic Background & Achievements
- 2009.9-2014.6 PhD: Fudan University
- 2005.9-2009.7 Bachelor's: Shandong University
- 2006.7-2007.7 Exchange Student: Xiamen University
Publications
- A distinct assembly pathway of the human 39S late pre-mitoribosome, Cheng J, Berninghausen O, Beckmann R, 2023
- Structural basis of L-tryptophan-dependent inhibition of Release Factor 2 by the TnaC arrest peptide, Su T, Kudva R, Becker T, Buschauer R, Komar T, Berninghausen O, Heijne G, Cheng J, Beckmann R, 2023
- Architecture of the active post-translational Sec translocon, Weng T, Steinchen W, Beatrix B, Berninghausen O, Becker T, Bange G, Cheng J, Beckmann R, 2021
- Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes, Wells JN, Buschauer R, Mackens-Kiani T, Best K, Kratzat H, Berninghausen O, Becker T, Gilbert W, Cheng J, Beckmann R, 2020
- Structure of the maturing 90S pre-ribosome in association with the RNA exosome, Lau B, Cheng J, Flemming D, La Venuta G, Berninghausen O, Beckmann R, Hurt E, 2021
- 90S pre-ribosome transformation into the primordial 40S subunit, Cheng J, Lau B, La Venuta G, Ameismeier M, Berninghausen O, Hurt E, Beckmann R, 2020
- Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration, Cheng J, Baßler J, Fischer P, Lau B, Kellner N, Kunze R, Griesel S, Kallas M, Berninghausen O, Strauss D, Beckmann R, Hurt E, 2019
- Visualizing late states of human 40S ribosomal subunit maturation, Ameismeier M, Cheng J, Berninghausen O, Beckmann R, 2018
- 3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage, Cheng J, Kellner N, Berninghausen O, Hurt E, Beckmann R, 2017
- Structural insight into substrate preference for TET-mediated oxidation, Hu L, Lu J, Cheng J, Rao Q, Li Z, Hou H, Lou Z, Zhang L, Li W, Gong W, Liu M, Sun C, Yin X, Li J, Tan X, Wang P, Wang Y, Fang D, Cui Q, Yang P, He C, Jiang H, Luo C, Xu Y, 2015
- Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation, Hu L, Li Z, Cheng J, Rao Q, Gong W, Liu M, Shi YG, Zhu J, Wang P, Xu Y, 2013
- Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation, Cheng J, Yang H, Fang J, Ma L, Gong R, Wang P, Li Z, Xu Y, 2015
Awards
- Römer-Preise (2018): University of Munich
- First Prize in Natural Science by Ministry of Education (2016): 4/5
- National Scholarship (2013)
