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Qianhui Qu
qqh@fudan.edu.cn
Chinese, English
Shanghai
Fudan University
Biomedical Sciences
  • 2009-2012 PhD: Institute of Biophysics, Chinese Academy of Sciences, Biochemistry and Molecular Biology
  • 2006-2009 Master's: Institute of Biophysics, Chinese Academy of Sciences, Biochemistry and Molecular Biology
  • 2002-2006 Bachelor's: Wuhan University, School of Life Sciences
  • 2020.12-Present - Fudan University, School of Stomatology/Affiliated Stomatological Hospital - Researcher
  • 2020.9-Present - Fudan University, Institute of Biomedical Sciences/School of Basic Medical Sciences, Department of Systems Biology - Young Researcher
  • 2017.6-2020.8 - Stanford University - Research Scientist
  • 2016.1-2017.5 - University of Michigan - Postdoctoral Fellow
  • 2012.9-2016.1 - University of Texas Southwestern Medical Center - Postdoctoral Fellow
Neural signal transduction processes, especially membrane protein receptors such as GPCRs and transport proteins related to human physiological functions and disease development.
  • Transport and inhibition mechanism for VMAT2-mediated synaptic vesicle loading of monoamines, Yuwei Wang, Pei Zhang, Yulin Chao, Zhini Zhu, Chuanhui Yang, Zixuan Zhou, Yaohui Li, Yonghui Long, Yuehua Liu, Dianfan Li, Sheng Wang, Qianhui Qu, 2024
  • Molecular basis of the inositol deacylase PGAP1 involved in quality control of GPI-AP biogenesis, Jingjing Hong, Tingting Li, Yulin Chao, Yidan Xu, Zhini Zhu, Zixuan Zhou, Weijie Gu, Qianhui Qu, Dianfan Li, 2024
  • Structures of substrates- and products-bound glycosylphophatidylinositol transamidase illuminate GPI-AP biogenesis, Yidan Xu, Tingting Li, Zixuan Zhou, Jingjing Hong, Yulin Chao, Zhini Zhu, Ying Zhang, Qianhui Qu, Dianfan Li, 2023
  • Cryo-EM structure of the RuvAB-Holiday junction intermediate complex from Pseudomonas aeruginosa, Xu Zhang, Zixuan Zhou, Lin Dai, Yulin Chao, Zheng Liu, Mingdong Huang, Qianhui Qu, Zhonghui Lin, 2023
  • Molecular insights into the biogenesis of glycosylphosphatidylinositol anchor proteins, Yidan Xu, Guowen Jia, Tingting Li, Zixuan Zhou, Yitian Luo, Yulin Chao, Juan Bao, Zhaoming Su, Qianhui Qu, Dianfan Li, 2022
  • Cryo-EM study of patched in lipid nanodisc suggests a structural basis for its clustering in caveolae, Yitian Luo, Guoyue Wan, Xiang Zhang, Xuan Zhou, Qiuwen Wang, Jialin Fan, Hongmin Cai, Liya Ma, Hailong Wu, Qianhui Qu, Yao Cong, Yun Zhao, Dianfan Li, 2021
  • Insights into distinct signaling profiles of the μOR activated by diverse agonists, Qianhui Qu, Weijiao Huang, Deniz Aydin, Joseph M. Paggi, Alpay B. Seven, Haoqing Wang, Soumen Chakraborty, Tao Che, Jeffrey F. DiBerto, Michael J. Robertson, Asuka Inoue, Carl-Mikael Suomivuori, Bryan L. Roth, Susruta Majumdar, Ron O. Dror, Brian K. Kobilka, Georgios Skiniotis, 2023
  • Structure-based design of functionally selective bitopic ligands for the μ-opioid receptor, Abdelfattah Faouzi, Haoqing Wang, Saheem A. Zaidi, Tao Che, Jeffrey F. DiBerto, Qianhui Qu, Michael J. Robertson, Manish K. Madasu, Amal El Daibani, Balazs R. Varga, Kevin Appourchaux, Tiffany Zhang, Samuel T. Slocum, Shainnel O. Eans, Ream Al-Hasani, Ying Xian Pan, Bryan L. Roth, Jay P. McLaughlin, Georgios Skiniotis, Vsevolod Katritch, Brian K. Kobilka, Susruta Majumdar, 2023
  • Structure-based Evolution of G protein-biased μ-opioid Receptor Agonists, Haoqing Wang, Florian Hetzer, Weijiao Huang, Qianhui Qu, Justin Meyerowitz, Jonas Kaindl, Harald Hübner, Georgios Skiniotis, Brian K. Kobilka, Peter Gmeiner, 2022
  • Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins, Naotaka Tsutsumi, Shoji Maeda, Qianhui Qu, Martin Vögele, Kevin M Jude, Carl-Mikael Suomivuori, Ouliana Panova, Deepa Waghray, Hideaki E Kato, Andrew Velasco, Ron O Dror, Georgios Skiniotis, Brian K Kobilka, K Christopher Garcia, 2022
  • Structure and mechanism of the SGLT family of glucose transporters, Lei Han, Qianhui Qu, Deniz Aydin, Ouliana Panova, Michael J. Robertson, Yan Xu, Ron O. Dror, Georgios Skiniotis, Liang Feng, 2022
  • Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1, Naotaka Tsutsumi, Qianhui Qu, Masa Mavri, Maibritt Baggesen, Shoji Maeda, Deepa Waghray, Christian Berg, Brian K. Kobilka, Mette M. Rosenkilde, Georgios Skiniotis, Christopher K Garcia, 2021
  • Structure of the Neurotensin Receptor 1 in complex with β-arrestin 1, Weijiao Huang, Matthieu Masureel, Qianhui Qu, John Janetzko, Asuka Inoue, Khanh Nguyen, Hideaki Kato, Jeffrey Glenn, Michael Robertson, Georgios Skiniotis, Brian K. Kobilka, 2020
  • Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes, Shoji Maeda, Qianhui Qu, Michael J. Robertson, Georgios Skiniotis, Brian K. Kobilka, 2019
  • SET de-protects centromeric cohesion through inhibiting interaction of Sgo1 and cohesin, Qianhui Qu, Qian Zhang, Lu Yang, Xiaofeng Zhu, Hong Liu, 2019
  • Structure and conformational dynamics of COMPASS histone H3K4 methyltransferase, Qianhui Qu, Yohhei Takahashi, Yidai Yang, Hongli Hu, Yan Zhang, Joseph S Brunzelle, Jean-François Couture, Ali Shilatifard, Georgios Skiniotis, 2018
Neural Signal Transduction Membrane Protein Receptors Gpcr Transport Proteins Human Physiology Disease Development Structural Biology Cryo-Em X-Ray Crystallography Biochemistry

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