Areas of Focus
- Interaction and coordination of non-coding RNA and chromatin modification
Work Experience
- 2001-2007 - Postdoctoral Researcher - Uppsala University and Johns Hopkins University
- 2007-11 - Faculty and Associate Research Scientist - Columbia University, USA
- Current - PI and Researcher - Fudan University, Executive Deputy Director of Genomics and Epigenomics Institute
Academic Background & Achievements
- 1989 - Bachelor's Degree in Medicine: Fourth Military Medical University
- 2001 - Doctorate: Fourth Military Medical University
- Postdoctoral Research: Uppsala University, Sweden and Johns Hopkins University, USA
Publications
- Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA, Yu W, Gius D, Onyango P, Muldoon-Jacobs K, Karp J, Feinberg AP, Cui H, 2008
- Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation, Yu W, Ginjala V, Pant V, Chernukhin I, Whitehead J, Docquier F, Farrar D, Tavoosidana G, Mukhopadhyay R, Kanduri C, Oshimura M, Feinberg AP, Lobanenkov V, Klenova E, Ohlsson R, 2004
- Intra-individual change over time in DNA methylation with familial clustering, Bjornsson HT, Sigurdsson MI, Fallin MD, Irizarry RA, Aspelund T, Cui H, Yu W, Rongione MA, Ekström TJ, Harris TB, Launer LJ, Eiriksdottir G, Leppert MF, Sapienza C, Gudnason V, Feinberg AP, 2008
- The binding sites for the chromatin insulator protein CTCF map to DNA methylation-free domains genome-wide, Mukhopadhyay R, Yu W, Whitehead J, Xu J, Lezcano M, Pack S, Kanduri C, Kanduri M, Ginjala V, Vostrov A, Quitschke W, Chernukhin I, Klenova E, Lobanenkov V, Ohlsson R, 2004
- DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation, Sun L, Huang L, Nguyen P, Bisht KS, Bar-Sela G, Ho AS, Bradbury CM, Yu W, Cui H, Lee S, Trepel JB, Feinberg AP, Gius D, 2008
- CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide, Chernukhin I, Shamsuddin S, Kang SY, Bergström R, Kwon YW, Yu W, Whitehead J, Mukhopadhyay R, Docquier F, Farrar D, Morrison I, Vigneron M, Wu SY, Chiang CM, Loukinov D, Lobanenkov V, Ohlsson R, Klenova E, 2007
Awards
- Research published in Nature, Nature Genetics, JAMA