Professor | Jie Liu | Asia Growth Partners

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Name	Jie Liu
Contact Information	jieliu@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Jie Liu

Contact Information

jieliu@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Biomedical Sciences
Academic Background & Achievements	1996-1999 PhD: Fourth Military Medical University, Internal Medicine 1990-1993 Master's: Fourth Military Medical University, Internal Medicine 1982-1987 Bachelor's: Fourth Military Medical University, Clinical Medicine National Outstanding Youth Science Fund New Century Talents Project 'National Level' Candidate State Council 'Special Government Allowance' Shanghai 'Outstanding Academic Leader' Shanghai 'Leading Talent'
Work Experience	2009.10-Present - Fudan University, Huashan Hospital - Professor, Chief Physician 2003.2-2009.09 - Fourth Military Medical University, Xijing Hospital - Associate Chief Physician/Chief Physician 2000.09-2003.01 - Thomas Jefferson University - Postdoctoral Researcher
Awards	National Science and Technology Progress Award First Prize (Fifth Contributor): Ministry of Education Shanghai Excellent Invention Silver Award: Shanghai Association for Science and Technology

University/Lab Affiliation and Title

Fudan University

Faculty

Biomedical Sciences

Academic Background & Achievements

1996-1999 PhD: Fourth Military Medical University, Internal Medicine
1990-1993 Master's: Fourth Military Medical University, Internal Medicine
1982-1987 Bachelor's: Fourth Military Medical University, Clinical Medicine
National Outstanding Youth Science Fund
New Century Talents Project 'National Level' Candidate
State Council 'Special Government Allowance'
Shanghai 'Outstanding Academic Leader'
Shanghai 'Leading Talent'

Work Experience

2009.10-Present - Fudan University, Huashan Hospital - Professor, Chief Physician
2003.2-2009.09 - Fourth Military Medical University, Xijing Hospital - Associate Chief Physician/Chief Physician
2000.09-2003.01 - Thomas Jefferson University - Postdoctoral Researcher

Awards

National Science and Technology Progress Award First Prize (Fifth Contributor): Ministry of Education
Shanghai Excellent Invention Silver Award: Shanghai Association for Science and Technology

Areas of Focus	Inflammation, Metabolism, and Cancer Basic Research Clinical Translation and Precision Medicine
Publications	5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers, Li, W., Zhang, X., Lu, X., You, L., Song, Y., Luo, Z., Zhang, J., Nie, J., Zheng, W., Xu, D., Wang, Y., Dong, Y., Yu, S., Hong, J., Shi, J., Hao, H., Luo, F., Hua, L., Wang, P., Qian, X., Yuan, F., Wei, L., Cui, M., Zhang, T., Liao, Q., Dai, M., Liu, Z., Chen, G., Meckel, K., Adhikari, S., Jia, G., Bissonnette, M.B., Zhang, X., Zhao, Y., Zhang, W., He, C., Liu, J., 2017 Bifunctional alphaHER2/CD3 RNA-engineered CART-like human T cells specifically eliminate HER2(+) gastric cancer, Luo, F., Qian, J., Yang, J., Deng, Y., Zheng, X., Liu, J., and Chu, Y., 2016 Hippocalcin-like 1 suppresses hepatocellular carcinoma progression by promoting p21 stabilization by activating the ERK1/2-MAPK pathway, Zhang, Y., Liu, Y., Duan, J., Yan, H., Zhang, J., Zhang, H., Fan, Q., Luo, F., Yan, G., Qiao, K., and Liu, J., 2016 The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth, Luo, Z., Yu, G., Lee, H.W., Li, L., Wang, L., Yang, D., Pan, Y., Ding, C., Qian, J., Wu, L., Chu, Y., Yi, J., Wang, X., Sun, Y., Jeong, L.S., Liu, J., and Jia, L., 2012 Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells, Yang, D., Li, L., Liu, H., Wu, L., Luo, Z., Li, H., Zheng, S., Gao, H., Chu, Y., Sun, Y., Liu, J., and Jia, L., 2013 The novel protective role of P27 in MLN4924-treated gastric cancer cells, Zhang, Q., Hou, D., Luo, Z., Chen, P., Lv, B., Wu, L., Ma, Y., Chu, Y., Liu, H., Liu, F., Yu, S., Zhang, J., Yang, D., and Liu, J., 2015 Blocking preferential glucose uptake sensitizes liver tumor-initiating cells to glucose restriction and sorafenib treatment, Zhang, H.L., Wang, M.D., Zhou, X., Qin, C.J., Fu, G.B., Tang, L., Wu, H., Huang, S., Zhao, L.H., Zeng, M., Liu, J., Cao, D., Guo, L.N., Wang, H.Y., Yan, H.X., and Liu, J., 2017 Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells, Yang, H., Shi, L., Wang, B.A., Liang, D., Zhong, C., Liu, W., Nie, Y., Liu, J., Zhao, J., Gao, X., Li, D., Xu, G.L., and Li, J., 2012 S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites, Deng, J., Liu, Y., Lee, H., Herrmann, A., Zhang, W., Zhang, C., Shen, S., Priceman, S.J., Kujawski, M., Pal, S.K., Raubitschek, A., Hoon, D.S., Forman, S., Figlin, R.A., Liu, J., Jove, R., and Yu, H., 2012 NADP(+)-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance, Li, F., He, X., Ye, D., Lin, Y., Yu, H., Yao, C., Huang, L., Zhang, J., Wang, F., Xu, S., Wu, X., Liu, L., Yang, C., Shi, J., He, X., Liu, J., Qu, Y., Guo, F., Zhao, J., Xu, W., and Zhao, S., 2015 Hepatitis B x antigen up-regulates vascular endothelial growth factor receptor 3 in hepatocarcinogenesis, Lian, Z., Liu, J., Wu, M., Wang, H.Y., Arbuthnot, P., Kew, M., and Feitelson, M.A., 2007 Hepatitis B in China, Liu, J., and Fan, D.M., 2007 Downregulation of E-cadherin by hepatitis B virus X antigen in hepatocellullar carcinoma, Liu, J., Lian, Z., Han, S., Waye, M.M., Wang, H., Wu, M.C., Wu, K., Ding, J., Arbuthnot, P., Kew, M., Fan, D., and Feitelson, M.A., 2006 COX2-related multicentric mixed-type Castleman's disease in a young man, Liu, J., Han, S., Ding, J., Wu, K., Miao, J., and Fan, D., 2005

Areas of Focus

Inflammation, Metabolism, and Cancer
Basic Research
Clinical Translation and Precision Medicine

Publications

5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers, Li, W., Zhang, X., Lu, X., You, L., Song, Y., Luo, Z., Zhang, J., Nie, J., Zheng, W., Xu, D., Wang, Y., Dong, Y., Yu, S., Hong, J., Shi, J., Hao, H., Luo, F., Hua, L., Wang, P., Qian, X., Yuan, F., Wei, L., Cui, M., Zhang, T., Liao, Q., Dai, M., Liu, Z., Chen, G., Meckel, K., Adhikari, S., Jia, G., Bissonnette, M.B., Zhang, X., Zhao, Y., Zhang, W., He, C., Liu, J., 2017
Bifunctional alphaHER2/CD3 RNA-engineered CART-like human T cells specifically eliminate HER2(+) gastric cancer, Luo, F., Qian, J., Yang, J., Deng, Y., Zheng, X., Liu, J., and Chu, Y., 2016
Hippocalcin-like 1 suppresses hepatocellular carcinoma progression by promoting p21 stabilization by activating the ERK1/2-MAPK pathway, Zhang, Y., Liu, Y., Duan, J., Yan, H., Zhang, J., Zhang, H., Fan, Q., Luo, F., Yan, G., Qiao, K., and Liu, J., 2016
The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth, Luo, Z., Yu, G., Lee, H.W., Li, L., Wang, L., Yang, D., Pan, Y., Ding, C., Qian, J., Wu, L., Chu, Y., Yi, J., Wang, X., Sun, Y., Jeong, L.S., Liu, J., and Jia, L., 2012
Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells, Yang, D., Li, L., Liu, H., Wu, L., Luo, Z., Li, H., Zheng, S., Gao, H., Chu, Y., Sun, Y., Liu, J., and Jia, L., 2013
The novel protective role of P27 in MLN4924-treated gastric cancer cells, Zhang, Q., Hou, D., Luo, Z., Chen, P., Lv, B., Wu, L., Ma, Y., Chu, Y., Liu, H., Liu, F., Yu, S., Zhang, J., Yang, D., and Liu, J., 2015
Blocking preferential glucose uptake sensitizes liver tumor-initiating cells to glucose restriction and sorafenib treatment, Zhang, H.L., Wang, M.D., Zhou, X., Qin, C.J., Fu, G.B., Tang, L., Wu, H., Huang, S., Zhao, L.H., Zeng, M., Liu, J., Cao, D., Guo, L.N., Wang, H.Y., Yan, H.X., and Liu, J., 2017
Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells, Yang, H., Shi, L., Wang, B.A., Liang, D., Zhong, C., Liu, W., Nie, Y., Liu, J., Zhao, J., Gao, X., Li, D., Xu, G.L., and Li, J., 2012
S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites, Deng, J., Liu, Y., Lee, H., Herrmann, A., Zhang, W., Zhang, C., Shen, S., Priceman, S.J., Kujawski, M., Pal, S.K., Raubitschek, A., Hoon, D.S., Forman, S., Figlin, R.A., Liu, J., Jove, R., and Yu, H., 2012
NADP(+)-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance, Li, F., He, X., Ye, D., Lin, Y., Yu, H., Yao, C., Huang, L., Zhang, J., Wang, F., Xu, S., Wu, X., Liu, L., Yang, C., Shi, J., He, X., Liu, J., Qu, Y., Guo, F., Zhao, J., Xu, W., and Zhao, S., 2015
Hepatitis B x antigen up-regulates vascular endothelial growth factor receptor 3 in hepatocarcinogenesis, Lian, Z., Liu, J., Wu, M., Wang, H.Y., Arbuthnot, P., Kew, M., and Feitelson, M.A., 2007
Hepatitis B in China, Liu, J., and Fan, D.M., 2007
Downregulation of E-cadherin by hepatitis B virus X antigen in hepatocellullar carcinoma, Liu, J., Lian, Z., Han, S., Waye, M.M., Wang, H., Wu, M.C., Wu, K., Ding, J., Arbuthnot, P., Kew, M., Fan, D., and Feitelson, M.A., 2006
COX2-related multicentric mixed-type Castleman's disease in a young man, Liu, J., Han, S., Ding, J., Wu, K., Miao, J., and Fan, D., 2005

Inflammation Metabolism Cancer Amino Acid Metabolism Gut-Liver Axis Microbiome Epigenetics Ubiquitin System Lipid Metabolism Digestive System Tumors

Xianghuo He - Fudan University

Qunying Lei - Fudan University

Yujiang Geno Shi - Fudan University

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