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Baidong Hou
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
B Cells
Immune Response
Novel Antigens
Epigenetics
Transcriptional Regulation
Immune Repertoire
Disease
Vaccines
Pathogen-Like Antigens
Synthetic Biology
Areas of Focus
- B cell immune response to novel antigens
- Epigenetic and transcriptional regulation of B cell differentiation
- Immune repertoire and disease
- New concept vaccines
Academic Background & Achievements
- 1997-09 - Medical Doctor: Peking Union Medical College
- 1989-08 - Medical Bachelor: Peking University Health Science Center
Publications
- B cells are the dominant antigen-presenting cells that activate naïve CD4+ T cells upon immunization with a virus-derived nanoparticle antigen., Hong S, Zhang Zhimin, Liu H, Tian M, Zhu X, Zhang Zhuqiang, Wang W, Zhu B, Zhou X, Zhang F, Ge Q, Tang H, Hua Z, Hou B, 2018
- B Cell-Intrinsic MyD88 Signaling Promotes Initial Cell Proliferation and Differentiation To Enhance the Germinal Center Response to a Virus-like Particle., Tian M, Hua Z, Hong S, Liu C, Lin L, Chen J, Zhang Z, Zhang W, Zhou X, Zhang F, DeFranco AL, Hou B, 2018
- Characterization of T-dependent and T-independent B cell response to a virus-like particle antigen., Liao W, Hua Z, Liu C, Lin L, Chen R, Hou B, 2017
- Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice., Hua Z, Gross AJ, Lamagna C, Ramos-Hernández N, Scapini P, Ji M, Shao H, Lowell CA, Hou B, DeFranco AL, 2014
- Selective utilization of TLR/MyD88 signaling in B cells for enhancement of the anti-viral germinal center response., Hou B, Saudan P, Ott G, Wheeler ML, Ji M, Kuzmich L, Lee L, Coffman R, Bachmann M, DeFranco AL, 2011
