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侯百东
Life Science
中国科学院大学
北京
Language: 中文, 英语
B细胞
免疫反应
新型抗原
表观遗传
转录调控
免疫图谱
疾病
疫苗
病原样抗原
合成生物学
Areas of Focus
- 新型抗原的B细胞免疫反应
- B细胞分化的表观遗传和转录调控
- 免疫图谱与疾病
- 新概念疫苗
Academic Background & Achievements
- 1997-09 - 医学博士: 中国协和医科大学
- 1989-08 - 医学学士: 北京医科大学
Publications
- B cells are the dominant antigen-presenting cells that activate naïve CD4+ T cells upon immunization with a virus-derived nanoparticle antigen., Hong S, Zhang Zhimin, Liu H, Tian M, Zhu X, Zhang Zhuqiang, Wang W, Zhu B, Zhou X, Zhang F, Ge Q, Tang H, Hua Z, Hou B, 2018
- B Cell-Intrinsic MyD88 Signaling Promotes Initial Cell Proliferation and Differentiation To Enhance the Germinal Center Response to a Virus-like Particle., Tian M, Hua Z, Hong S, Liu C, Lin L, Chen J, Zhang Z, Zhang W, Zhou X, Zhang F, DeFranco AL, Hou B, 2018
- Characterization of T-dependent and T-independent B cell response to a virus-like particle antigen., Liao W, Hua Z, Liu C, Lin L, Chen R, Hou B, 2017
- Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice., Hua Z, Gross AJ, Lamagna C, Ramos-Hernández N, Scapini P, Ji M, Shao H, Lowell CA, Hou B, DeFranco AL, 2014
- Selective utilization of TLR/MyD88 signaling in B cells for enhancement of the anti-viral germinal center response., Hou B, Saudan P, Ott G, Wheeler ML, Ji M, Kuzmich L, Lee L, Coffman R, Bachmann M, DeFranco AL, 2011
