Professor | Yan Qin | Asia Growth Partners

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Name	Yan Qin
Contact Information	qiny@ibp.ac.cn
Language ability	Chinese, German, English
Province	Beijing

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Name

Yan Qin

Contact Information

qiny@ibp.ac.cn

Language ability

Chinese, German, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	1995/09-1999/06 Bachelor's Degree: Nankai University, School of Life Sciences 2001/10-2003/04 Master's Degree: Free University of Berlin, Department of Chemistry 2003/05-2006/02 PhD: Max Planck Institute for Molecular Genetics/Free University of Berlin, Department of Chemistry 2006/03- Postdoctoral Research: Max Planck Institute for Molecular Genetics
Work Experience	2006-present - Institute of Biophysics, Chinese Academy of Sciences - Researcher, Chief Technical Expert of RNA Platform 2007-present - Institute of Biophysics, Chinese Academy of Sciences - Innovation Group Leader, Doctoral Supervisor, Professor at the Graduate School of the Chinese Academy of Sciences (Courses taught: Introduction to Structural Biology) 2014-present - University of Chinese Academy of Sciences - Professor (Courses taught: Molecular Biology)
Awards	Outstanding Youth: Regulation of Protein Translation in Mitochondria

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

1995/09-1999/06 Bachelor's Degree: Nankai University, School of Life Sciences
2001/10-2003/04 Master's Degree: Free University of Berlin, Department of Chemistry
2003/05-2006/02 PhD: Max Planck Institute for Molecular Genetics/Free University of Berlin, Department of Chemistry
2006/03- Postdoctoral Research: Max Planck Institute for Molecular Genetics

Work Experience

2006-present - Institute of Biophysics, Chinese Academy of Sciences - Researcher, Chief Technical Expert of RNA Platform
2007-present - Institute of Biophysics, Chinese Academy of Sciences - Innovation Group Leader, Doctoral Supervisor, Professor at the Graduate School of the Chinese Academy of Sciences (Courses taught: Introduction to Structural Biology)
2014-present - University of Chinese Academy of Sciences - Professor (Courses taught: Molecular Biology)

Awards

Outstanding Youth: Regulation of Protein Translation in Mitochondria

Areas of Focus	Ribosome Biology Cancer and Ribosome Relationship
Publications	TGF-β changes cyto/mito-ribosome balance to target respiratory chain complex V biogenesis in pulmonary fibrosis therapy, Na Zhang, Zunling Zhao, Yin Zhao, Lei Yang, Yanhong Xue, Yun Feng, Jianjun Luo, Runsheng Chen, Wei Wei, Yan Qin, 2023 Organelle biogenesis: ribosomes as organizer and performer, Wang, Qi, Wang, Yibo, Li, Shuoguo, Zhou, Aoqi, Qin, Yan, 2022 A male germ-cell-specific ribosome controls male fertility, 秦燕, 2022 The mTORC1-eIF4F axis controls paused pluripotency, Xu, Xueting, Ahmed, Tanveer, Wang, Lulu, Cao, Xintao, Zhang, Zeyu, Wang, Ming, Lv, Yuan, Kanwal, Shahzina, Tariq, Muqddas, Lin, Runxia, Zhang, Hui, Huang, Yinghua, Peng, Hao, Lin, Danni, Shi, Xue, Geng, Didi, Liu, Baohua, Zhang, Xiaofei, Yi, Wen, Qin, Yan, Esteban, Miguel A, Qin, Baoming, 2022 Amino porphyrin-peptide assemblies induce ribosome damage and cancer stem cell inhibition for an enhanced photodynamic therapy, Jian Wang, Baochan Yang, Chaofan Lv, Tiancheng Chen, Lixin Sun, Lei Sun, Junfeng Hao, Fang Ding, Tianyu Wang, Jianzhuang Jiang, Yan Qin, 2022 Modulated Ultrasmall γ-Fe2O3 Nanocrystal Assemblies for Switchable Magnetic Resonance Imaging and Photothermal-Ferroptotic-Chemical Synergistic Cancer Therapy, Baochan Yang, Yiming Zhang, lixin sun, Jian Wang, Zunling Zhao, Zhuoyue Huang, Wei Mao, Rong Xue, runsheng chen, jianjun luo, Tianyu Wang, jianzhuang jiang, Yan Qin, 2022 Nanofibrous composite aerogel with multi-bioactive and fluid gating characteristics for promoting diabetic wound healing, Zhang, Kexin, Jiao, Xiangyu, Zhou, Liping, Wang, Jian, Wang, Cheng, Qin, Yan, Wen, Yongqiang, 2021 beta-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus, Zhang, Meng, Lai, Yiwei, Krupalnik, Vladislav, Guo, Pengcheng, Guo, Xiangpeng, Zhou, Jianguo, Xu, Yan, Yu, Zhijun, Liu, Longqi, Jiang, Ao, Li, Wenjuan, Ma, Gang, Li, Na, Fu, Xiuling, Lv, Yuan, Jiang, Mengling, Tariq, Muqddas, Kanwal, Shahzina, Liu, Hao, Xu, Xueting, Zhang, Hui, Huang, Yinghua, Wang, Lulu, Chen, Shuhan, Babarinde, Isaac A, Luo, Zhiwei, Wang, Dongye, Zhou, Tiantian, Ward, Carl, He, Minghui, Ibanez, David P, Li, Yunpan, Zhou, Jiajian, Yuan, Jie, Feng, Yayan, Arumugam, Karthik, Di Vicino, Umberto, Bao, Xichen, Wu, Guangming, Schambach, Axel, Wang, Huating, Sun, Hao, Gao, Fei, Qin, Baoming, Hutchins, Andrew P, Doble, Bradley W, Hartmann, Christine, Cosma, Maria Pia, Qin, Yan, Xu, GuoLiang, Chen, Runsheng, Volpe, Giacomo, Chen, Liang, Hanna, Jacob H, Esteban, Miguel A, 2020 Cellular Nanofiber Structure with Secretory Activity-Promoting Characteristics for Multicellular Spheroid Formation and Hair Follicle Regeneration, Zhang, Kexin, Bai, Xiufeng, Yuan, Zhipeng, Cao, Xintao, Jiao, Xiangyu, Qin, Yan, Wen, Yongqiang, Zhang, Xueji, 2020 Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy, Wu, Hao, Wei, Huifang, Zhang, Di, Sehgal, Sheikh Arslan, Zhang, Dejiu, Wang, Xiaohui, Qin, Yan, Liu, Lei, Chen, Quan, 2020 Conformational activation of ribosome recycling by intra- and inter-molecular dynamics of RRF, Song, Guangtao, Xu, Benjin, Shi, Huigang, Zhang, Yong, Zhang, Dejiu, Cao, Xintao, Liu, Zengrui, Guo, Ran, Guan, YanZhong, Chu, Yanhui, Zhang, Xinzheng, Lou, Jizhong, Qin, Yan, 2020 Naringenin Enhances the Antitumor Effect of Therapeutic Vaccines by Promoting Antigen Cross-Presentation, Wang, Luoyang, Zeng, Wenfeng, Wang, Luyao, Wang, Zihao, Yin, Xiaozhe, Qin, Yan, Zhang, Fayun, Zhang, Chunling, Liang, Wei, 2020 Layered nanofiber sponge with an improved capacity for promoting blood coagulation and wound healing, Zhang, Kexin, Bai, Xiufeng, Yuan, Zhipeng, Cao, Xintao, Jiao, Xiangyu, Li, Yansheng, Qin, Yan, Wen, Yongqiang, Zhang, Xueji, 2019 A brief review: the mitochondrial translation factor EF4 regulated mitochondrial respiratory chain and induced the production of ROS, Yan Qin, 2019 AtTrm5a catalyses 1-methylguanosine and 1-methylinosine formation on tRNAs and is important for vegetative and reproductive growth in Arabidopsis thaliana, Jin, Xiaohuan, Lv, Zhengyi, Gao, Junbao, Zhang, Rui, Zheng, Ting, Yin, Ping, Li, Dongqin, Peng, Liangcai, Cao, Xintao, Qin, Yan, Persson, Staffan, Zheng, Bo, Chen, Peng, 2019 Genome wide analyses uncover allele-specific RNA editing in human and mouse, Zhou, ZhongYin, Hu, Yue, Li, Aimin, Li, YingJu, Zhao, Hui, Wang, SiQi, Otecko, Newton O, Zhang, Dejiu, Wang, JinHuan, Liu, Yajun, Irwin, David M, Qin, Yan, Zhang, YaPing, 2018 SmProt: a database of small proteins encoded by annotated coding and non-coding RNA loci, Hao, Yajing, Zhang, Lili, Niu, Yiwei, Cai, Tanxi, Luo, Jianjun, He, Shunmin, Zhang, Bao, Zhang, Dejiu, Qin, Yan, Yang, Fuquan, Chen, Runsheng, 2018 A novel class of microRNA-recognition elements that function only within open reading frames, Zhang, Kai, Zhang, Xiaorong, Cai, Zhiqiang, Zhou, Jie, Cao, Ran, Zhao, Ya, Chen, Zonggui, Wang, Dehe, Ruan, Wen, Zhao, Qian, Liu, Guangqiao, Xue, Yuanchao, Qin, Yan, Zhou, Bing, Wu, Ligang, Nilsen, Timothy, Zhou, Yu, Fu, XiangDong, 2018 Mitochondrial translation factor EF4 regulates oxidative phosphorylation complexes and the production of ROS, Li, Guichen, Qin, Yan, 2018 单分子荧光共振能量转移技术在核糖体移位研究中的进展, 徐本锦, 宋广涛, 秦燕, 2018 smFRET Study Progress in The Dynamics of Ribosome Translocation, Xu BenJin, Song GuangTao, Qin Yan, 2018 Stimuli-Responsive Nanocarrier for Co-delivery of MiR-31 and Doxorubicin To Suppress High MtEF4 Cancer, Wang, Fang, Zhang, Lingyun, Bai, Xiufeng, Cao, Xintao, Jiao, Xiangyu, Huang, Yan, Li, Yansheng, Qin, Yan, Wen, Yongqiang, 2018 Human Elongation Factor 4 Regulates Cancer Bioenergetics by Acting as a Mitochondrial Translation Switch, Zhu, Ping, Liu, Yongzhang, Zhang, Fenglin, Bai, Xiufeng, Chen, Zilei, Shangguan, Fugen, Zhang, Bo, Zhang, Lingyun, Chen, Qianqian, Xie, Deyao, Lan, Linhua, Xue, Xiangdong, Liang, XingJie, Lu, Bin, Wei, Taotao, Qin, Yan, 2018 CpG loaded MoS2 nanosheets as multifunctional agents for photothermal enhanced cancer immunotherapy, Han, Qiusen, Wang, Xinhuan, Jia, Xinghang, Cai, Shuangfei, Liang, Wei, Qin, Yan, Yang, Rong, Wang, Chen, 2017 Coordinating antigen cytosolic delivery and danger signaling to program potent cross-priming by micelle-based nanovaccine, Liu, Zhida, Zhou, Chang, Qin, Yan, Wang, Zihao, Wang, Luyao, Wei, Xiuli, Zhou, Yinjian, Li, Qicheng, Zhou, Hang, Wang, Wenjun, Fu, YangXin, Zhu, Mingzhao, Liang, Wei, 2017 SmProt: a database of small proteins encoded by annotated coding and non-coding RNA loci, Hao Y, Zhang L, Niu Y, Cai T, Luo JJ, He S, Zhang B, Zhang D, Qin Y, Yang Fuquan, Chen Runsheng, 2017

Areas of Focus

Ribosome Biology
Cancer and Ribosome Relationship

Publications

TGF-β changes cyto/mito-ribosome balance to target respiratory chain complex V biogenesis in pulmonary fibrosis therapy, Na Zhang, Zunling Zhao, Yin Zhao, Lei Yang, Yanhong Xue, Yun Feng, Jianjun Luo, Runsheng Chen, Wei Wei, Yan Qin, 2023
Organelle biogenesis: ribosomes as organizer and performer, Wang, Qi, Wang, Yibo, Li, Shuoguo, Zhou, Aoqi, Qin, Yan, 2022
A male germ-cell-specific ribosome controls male fertility, 秦燕, 2022
The mTORC1-eIF4F axis controls paused pluripotency, Xu, Xueting, Ahmed, Tanveer, Wang, Lulu, Cao, Xintao, Zhang, Zeyu, Wang, Ming, Lv, Yuan, Kanwal, Shahzina, Tariq, Muqddas, Lin, Runxia, Zhang, Hui, Huang, Yinghua, Peng, Hao, Lin, Danni, Shi, Xue, Geng, Didi, Liu, Baohua, Zhang, Xiaofei, Yi, Wen, Qin, Yan, Esteban, Miguel A, Qin, Baoming, 2022
Amino porphyrin-peptide assemblies induce ribosome damage and cancer stem cell inhibition for an enhanced photodynamic therapy, Jian Wang, Baochan Yang, Chaofan Lv, Tiancheng Chen, Lixin Sun, Lei Sun, Junfeng Hao, Fang Ding, Tianyu Wang, Jianzhuang Jiang, Yan Qin, 2022
Modulated Ultrasmall γ-Fe2O3 Nanocrystal Assemblies for Switchable Magnetic Resonance Imaging and Photothermal-Ferroptotic-Chemical Synergistic Cancer Therapy, Baochan Yang, Yiming Zhang, lixin sun, Jian Wang, Zunling Zhao, Zhuoyue Huang, Wei Mao, Rong Xue, runsheng chen, jianjun luo, Tianyu Wang, jianzhuang jiang, Yan Qin, 2022
Nanofibrous composite aerogel with multi-bioactive and fluid gating characteristics for promoting diabetic wound healing, Zhang, Kexin, Jiao, Xiangyu, Zhou, Liping, Wang, Jian, Wang, Cheng, Qin, Yan, Wen, Yongqiang, 2021
beta-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus, Zhang, Meng, Lai, Yiwei, Krupalnik, Vladislav, Guo, Pengcheng, Guo, Xiangpeng, Zhou, Jianguo, Xu, Yan, Yu, Zhijun, Liu, Longqi, Jiang, Ao, Li, Wenjuan, Ma, Gang, Li, Na, Fu, Xiuling, Lv, Yuan, Jiang, Mengling, Tariq, Muqddas, Kanwal, Shahzina, Liu, Hao, Xu, Xueting, Zhang, Hui, Huang, Yinghua, Wang, Lulu, Chen, Shuhan, Babarinde, Isaac A, Luo, Zhiwei, Wang, Dongye, Zhou, Tiantian, Ward, Carl, He, Minghui, Ibanez, David P, Li, Yunpan, Zhou, Jiajian, Yuan, Jie, Feng, Yayan, Arumugam, Karthik, Di Vicino, Umberto, Bao, Xichen, Wu, Guangming, Schambach, Axel, Wang, Huating, Sun, Hao, Gao, Fei, Qin, Baoming, Hutchins, Andrew P, Doble, Bradley W, Hartmann, Christine, Cosma, Maria Pia, Qin, Yan, Xu, GuoLiang, Chen, Runsheng, Volpe, Giacomo, Chen, Liang, Hanna, Jacob H, Esteban, Miguel A, 2020
Cellular Nanofiber Structure with Secretory Activity-Promoting Characteristics for Multicellular Spheroid Formation and Hair Follicle Regeneration, Zhang, Kexin, Bai, Xiufeng, Yuan, Zhipeng, Cao, Xintao, Jiao, Xiangyu, Qin, Yan, Wen, Yongqiang, Zhang, Xueji, 2020
Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy, Wu, Hao, Wei, Huifang, Zhang, Di, Sehgal, Sheikh Arslan, Zhang, Dejiu, Wang, Xiaohui, Qin, Yan, Liu, Lei, Chen, Quan, 2020
Conformational activation of ribosome recycling by intra- and inter-molecular dynamics of RRF, Song, Guangtao, Xu, Benjin, Shi, Huigang, Zhang, Yong, Zhang, Dejiu, Cao, Xintao, Liu, Zengrui, Guo, Ran, Guan, YanZhong, Chu, Yanhui, Zhang, Xinzheng, Lou, Jizhong, Qin, Yan, 2020
Naringenin Enhances the Antitumor Effect of Therapeutic Vaccines by Promoting Antigen Cross-Presentation, Wang, Luoyang, Zeng, Wenfeng, Wang, Luyao, Wang, Zihao, Yin, Xiaozhe, Qin, Yan, Zhang, Fayun, Zhang, Chunling, Liang, Wei, 2020
Layered nanofiber sponge with an improved capacity for promoting blood coagulation and wound healing, Zhang, Kexin, Bai, Xiufeng, Yuan, Zhipeng, Cao, Xintao, Jiao, Xiangyu, Li, Yansheng, Qin, Yan, Wen, Yongqiang, Zhang, Xueji, 2019
A brief review: the mitochondrial translation factor EF4 regulated mitochondrial respiratory chain and induced the production of ROS, Yan Qin, 2019
AtTrm5a catalyses 1-methylguanosine and 1-methylinosine formation on tRNAs and is important for vegetative and reproductive growth in Arabidopsis thaliana, Jin, Xiaohuan, Lv, Zhengyi, Gao, Junbao, Zhang, Rui, Zheng, Ting, Yin, Ping, Li, Dongqin, Peng, Liangcai, Cao, Xintao, Qin, Yan, Persson, Staffan, Zheng, Bo, Chen, Peng, 2019
Genome wide analyses uncover allele-specific RNA editing in human and mouse, Zhou, ZhongYin, Hu, Yue, Li, Aimin, Li, YingJu, Zhao, Hui, Wang, SiQi, Otecko, Newton O, Zhang, Dejiu, Wang, JinHuan, Liu, Yajun, Irwin, David M, Qin, Yan, Zhang, YaPing, 2018
SmProt: a database of small proteins encoded by annotated coding and non-coding RNA loci, Hao, Yajing, Zhang, Lili, Niu, Yiwei, Cai, Tanxi, Luo, Jianjun, He, Shunmin, Zhang, Bao, Zhang, Dejiu, Qin, Yan, Yang, Fuquan, Chen, Runsheng, 2018
A novel class of microRNA-recognition elements that function only within open reading frames, Zhang, Kai, Zhang, Xiaorong, Cai, Zhiqiang, Zhou, Jie, Cao, Ran, Zhao, Ya, Chen, Zonggui, Wang, Dehe, Ruan, Wen, Zhao, Qian, Liu, Guangqiao, Xue, Yuanchao, Qin, Yan, Zhou, Bing, Wu, Ligang, Nilsen, Timothy, Zhou, Yu, Fu, XiangDong, 2018
Mitochondrial translation factor EF4 regulates oxidative phosphorylation complexes and the production of ROS, Li, Guichen, Qin, Yan, 2018
单分子荧光共振能量转移技术在核糖体移位研究中的进展, 徐本锦, 宋广涛, 秦燕, 2018
smFRET Study Progress in The Dynamics of Ribosome Translocation, Xu BenJin, Song GuangTao, Qin Yan, 2018
Stimuli-Responsive Nanocarrier for Co-delivery of MiR-31 and Doxorubicin To Suppress High MtEF4 Cancer, Wang, Fang, Zhang, Lingyun, Bai, Xiufeng, Cao, Xintao, Jiao, Xiangyu, Huang, Yan, Li, Yansheng, Qin, Yan, Wen, Yongqiang, 2018
Human Elongation Factor 4 Regulates Cancer Bioenergetics by Acting as a Mitochondrial Translation Switch, Zhu, Ping, Liu, Yongzhang, Zhang, Fenglin, Bai, Xiufeng, Chen, Zilei, Shangguan, Fugen, Zhang, Bo, Zhang, Lingyun, Chen, Qianqian, Xie, Deyao, Lan, Linhua, Xue, Xiangdong, Liang, XingJie, Lu, Bin, Wei, Taotao, Qin, Yan, 2018
CpG loaded MoS2 nanosheets as multifunctional agents for photothermal enhanced cancer immunotherapy, Han, Qiusen, Wang, Xinhuan, Jia, Xinghang, Cai, Shuangfei, Liang, Wei, Qin, Yan, Yang, Rong, Wang, Chen, 2017
Coordinating antigen cytosolic delivery and danger signaling to program potent cross-priming by micelle-based nanovaccine, Liu, Zhida, Zhou, Chang, Qin, Yan, Wang, Zihao, Wang, Luyao, Wei, Xiuli, Zhou, Yinjian, Li, Qicheng, Zhou, Hang, Wang, Wenjun, Fu, YangXin, Zhu, Mingzhao, Liang, Wei, 2017
SmProt: a database of small proteins encoded by annotated coding and non-coding RNA loci, Hao Y, Zhang L, Niu Y, Cai T, Luo JJ, He S, Zhang B, Zhang D, Qin Y, Yang Fuquan, Chen Runsheng, 2017

Protein Synthesis Ribosome Biogenesis Mechanism Cancer Disease Model Diagnosis Treatment Translation Regulation Stem Cell Differentiation

Gao Ning - Peking University

Yihua Huang - University of Chinese Academy of Sciences

Yihua Huang - University of Chinese Academy of Sciences

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