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Xiaozhou Luo
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: English, Chinese
Directed Evolution
Protein Engineering
High-Throughput Screening
Biosynthesis
Natural Compounds
Non-Natural Compounds
Synthetic Biology
Enzyme Engineering
Metabolic Engineering
Biotechnology
Areas of Focus
- Directed Evolution
- Protein Engineering
- High-Throughput Screening
- Biosynthesis of Natural and Non-Natural Compounds
Work Experience
- 2019-09~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Researcher
- 2016-09~2019-09 - The Scripps Research Institute - Postdoctoral Researcher
- 2016-09~2019-09 - University of California, Berkeley - Postdoctoral Researcher
Academic Background & Achievements
- 2010-08--2016-05 PhD: The Scripps Research Institute
- 2006-08--2010-05 Bachelor: Nanyang Technological University
Publications
- Elucidation of genes enhancing natural product biosynthesis through co - evolution analysis, Corresponding Author, 2024
- Co-evolved genes improve the biosynthesis of secondary metabolites, Second Author, 2024
- Engineering yeast for the de novo synthesis of jasmonates, Corresponding Author, 2024
- Pathway Evolution Through a Bottlenecking ‐ Debottlenecking Strategy and Machine Learning ‐Aided Flux Balancing, Corresponding Author, 2024
- UniKP: a unified framework for the prediction of enzyme kinetic parameters, Corresponding Author, 2023
- One-pot selective biosynthesis of Tyrian purple in Escherichia coli, Corresponding Author, 2023
- Dynamic upregulation of the rate -limiting enzyme for valerolactam biosynthesis in Corynebacterium glutamicum, Corresponding Author, 2023
- Systematic genetic modifications of cell wall biosynthesis enhanced the secretion and surface -display of polysaccharide degrading enzymes in Saccharomyces cerevisiae, Corresponding Author, 2023
- Development of an efficient yeast platform for cannabigerolic acid biosynthesis, Corresponding Author, 2023
- IPPF-FE: an integrated peptide and protein function prediction framework based on fused features and ensemble models, Corresponding Author, 2023
- Creation of a Yeast Strain with Co - Translationally Acylated Nucleosomes, Corresponding Author, 2022
- Harnessing nature's biosynthetic capacity to facilitate total synthesis, Corresponding Author, 2022
- Machine learning for synthetic biology:Methods and applications, Sixth Author, 2021
- Metabolic engineering of Saccharomyces cerevisiae chassis, Fifth Author, 2021
- Expanding the Structural Diversity of Protein Building Blocks with Noncanonical Amino Acids Biosynthesized from Aromatic Thiols, Tenth Author, 2021
- Promoter Architecture and Promoter Engineering in Saccharomyces cerevisiae, Corresponding Author, 2020
- Promoter Architecture and Promoter Engineering in Saccharomyces cerevisiae, Seventh Author, 2020
- Complete biosynthesis of cannabinoids and their unnatural analogues in yeast, First Author, 2019
- Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria, First Author, 2017
- Recombinant thiopeptides containing noncanonical amino acids, First Author, 2016
- Stabilizing Protein Motifs with a Genetically Encoded Metal-Ion Chelator, First Author, 2016
