Professor | Yu Bo | Asia Growth Partners

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Name	Yu Bo
Contact Information	yub@im.ac.cn
Language ability	Chinese, English, German
Province	Beijing

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Name

Yu Bo

Contact Information

yub@im.ac.cn

Language ability

Chinese, English, German

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2001-09--2006-06 PhD: Shandong University 2008-2010 Postdoctoral: Helmholtz Centre for Infection Research, Germany 2008-2010 Postdoctoral: Hamburg University of Technology, Germany
Work Experience	2006-2008 - Chinese Academy of Sciences, Institute of Microbiology - Assistant Researcher 2010-2016 - Chinese Academy of Sciences, Institute of Microbiology - Associate Researcher, Young Research Group Leader 2016- - Chinese Academy of Sciences, Institute of Microbiology - Researcher, Research Group Leader

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2001-09--2006-06 PhD: Shandong University
2008-2010 Postdoctoral: Helmholtz Centre for Infection Research, Germany
2008-2010 Postdoctoral: Hamburg University of Technology, Germany

Work Experience

2006-2008 - Chinese Academy of Sciences, Institute of Microbiology - Assistant Researcher
2010-2016 - Chinese Academy of Sciences, Institute of Microbiology - Associate Researcher, Young Research Group Leader
2016- - Chinese Academy of Sciences, Institute of Microbiology - Researcher, Research Group Leader

Areas of Focus	Screening and application of extremophiles with industrial application potential Microbial synthesis technology and industrial development of bio-based platform chemicals Microbial synthesis of plant-derived compounds
Publications	One major facilitator superfamily transporter is responsible for propionic acid tolerance in Pseudomonas putida KT2440, Ma C, Mu QX, Xue YB, Xue YF, Yu B, Ma YH, 2020 Bio-production of high-purity propionate by engineering L-threonine degradation pathway in Pseudomonas putida, Ma C, Mu QX, Wang L, Shi YN, Zhu LF, Zhang SS, Xue YF, Tao Y, Ma YH, Yu B, 2020 Enhanced ε-poly-L-lysine production by the synergistic effect of ε-poly-L-lysine synthetase overexpression and citrate in Streptomyces albulus, Wang AX, Tian WZ, Cheng L, Xu YQ, Wang XW, Qin JY, Yu B, 2020 Biocatalytic production of D-p-hydroxyphenylglycine by optimizing protein expression and cell wall engineering in Escherichia coli, Liu Y, Zhu LF, Qi WP, Yu B, 2019 Biodetoxification of fungal mycotoxins zearalenone by engineered probiotic bacterium Lactobacillus reuteri with surface-displayed lactonohydrolase, Liu FX, Malaphan M, Xing FG, Yu B, 2019 A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts, Zheng Y#, Meng FK#, Zhu ZH, Wei WJ, Sun Z, Chen JC, Yu B, Lou CB, Chen GQ, 2019 Elucidating the role and regulation of a lactate permease as lactate transporter in Bacillus coagulans DSM1, Wang Y, Zhang CL, Liu GX, Ju JS, Yu B, Wang LM, 2019 Biotechnological routes for transglutaminase production: recent achievements, perspectives and limits, Wang LM, Yu B, Wang RX, Xie JC, 2018 Reconstructing biosynthetic pathway of the plant-derived cancer chemopreventive-precursor glucoraphanin in Escherichia coli, Yang H, Liu FX, Li Y, Yu B, 2018 Biosynthesis of the high-value plant secondary product benzyl isothiocyanate via functional expression of multiple heterologous enzymes in E. coli, Liu FX, Yang H, Wang LM, Yu B, 2016 Efficient production of enantiomerically pure D-phenyllactate from phenylpyruvate by structure-guided design of an engineered D-lactate dehydrogenase, Wang M#, Zhu LF#, Xu XL, Wang LM, Yin RC, Yu B, 2016 Diammonium phosphate stimulates transcription of L-lactate dehydrogenase leading to increased L-lactate production in the thermotolerant Bacillus coagulans strain, Sun LF, Li YF, Wang LM, Wang YP, Yu B, 2016 Efficient biodegradation of chlorophenols in aqueous phase by magnetically immobilized aniline-degrading Rhodococcus rhodochrous strain, Hou JF, Liu FX, Wu N, Ju JS, Yu B, 2016 Fermentative production of enantiomerically pure S-1,2-propanediol from glucose by engineered E. coli strain, Zhu LF#, Guan XC#, Xie NZ, Wang LM, Yu B, Ma YH, 2016 NADP+-preferring D-lactate dehydrogenase from Sporolactobacillus inulinus, Zhu LF, Xu XL, Wang LM, Dong H, Yu B, Ma YH, 2015 Efficient production of reuterin from glycerol by magnetically immobilized Lactobacillus reuterin, Liu FX, Yu B, 2015 Major role of NAD-dependent lactate dehydrogenases in high optically pure L-lactic acid production by thermophilic Bacillus coagulans, Wang LM#, Cai YM#, Zhu LF, Guo HL, Yu B, 2014 Bacillus sp. strain P38: an efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural, Peng LL, Wang LM, Che CC, Yang G, Yu B, Ma YH, 2013 Efficient production of polymer-grade D-lactate by Sporolactobacillus laevolacticus DSM442 with agricultural waste cottonseed as the sole nitrogen source, Li Y, Wang LM, Ju JS, Yu B, Ma YH, 2013 聚合级L-乳酸的非粮生物质发酵研究进展, 于波*，曾艳，姜旭，王丽敏，马延和, 2013

Areas of Focus

Screening and application of extremophiles with industrial application potential
Microbial synthesis technology and industrial development of bio-based platform chemicals
Microbial synthesis of plant-derived compounds

Publications

One major facilitator superfamily transporter is responsible for propionic acid tolerance in Pseudomonas putida KT2440, Ma C, Mu QX, Xue YB, Xue YF, Yu B*, Ma YH*, 2020
Bio-production of high-purity propionate by engineering L-threonine degradation pathway in Pseudomonas putida, Ma C, Mu QX, Wang L, Shi YN, Zhu LF, Zhang SS, Xue YF, Tao Y, Ma YH*, Yu B*, 2020
Enhanced ε-poly-L-lysine production by the synergistic effect of ε-poly-L-lysine synthetase overexpression and citrate in Streptomyces albulus, Wang AX, Tian WZ, Cheng L, Xu YQ, Wang XW, Qin JY, Yu B, 2020
Biocatalytic production of D-p-hydroxyphenylglycine by optimizing protein expression and cell wall engineering in Escherichia coli, Liu Y, Zhu LF, Qi WP, Yu B*, 2019
Biodetoxification of fungal mycotoxins zearalenone by engineered probiotic bacterium Lactobacillus reuteri with surface-displayed lactonohydrolase, Liu FX, Malaphan M, Xing FG, Yu B*, 2019
A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts, Zheng Y#, Meng FK#, Zhu ZH, Wei WJ, Sun Z, Chen JC, Yu B*, Lou CB*, Chen GQ*, 2019
Elucidating the role and regulation of a lactate permease as lactate transporter in Bacillus coagulans DSM1, Wang Y, Zhang CL, Liu GX, Ju JS, Yu B*, Wang LM*, 2019
Biotechnological routes for transglutaminase production: recent achievements, perspectives and limits, Wang LM*, Yu B, Wang RX, Xie JC, 2018
Reconstructing biosynthetic pathway of the plant-derived cancer chemopreventive-precursor glucoraphanin in Escherichia coli, Yang H, Liu FX, Li Y*, Yu B*, 2018
Biosynthesis of the high-value plant secondary product benzyl isothiocyanate via functional expression of multiple heterologous enzymes in E. coli, Liu FX, Yang H, Wang LM, Yu B*, 2016
Efficient production of enantiomerically pure D-phenyllactate from phenylpyruvate by structure-guided design of an engineered D-lactate dehydrogenase, Wang M#, Zhu LF#, Xu XL, Wang LM, Yin RC*, Yu B*, 2016
Diammonium phosphate stimulates transcription of L-lactate dehydrogenase leading to increased L-lactate production in the thermotolerant Bacillus coagulans strain, Sun LF, Li YF, Wang LM, Wang YP, Yu B*, 2016
Efficient biodegradation of chlorophenols in aqueous phase by magnetically immobilized aniline-degrading Rhodococcus rhodochrous strain, Hou JF, Liu FX, Wu N, Ju JS, Yu B*, 2016
Fermentative production of enantiomerically pure S-1,2-propanediol from glucose by engineered E. coli strain, Zhu LF#, Guan XC#, Xie NZ, Wang LM, Yu B*, Ma YH, 2016
NADP+-preferring D-lactate dehydrogenase from Sporolactobacillus inulinus, Zhu LF, Xu XL, Wang LM, Dong H*, Yu B*, Ma YH, 2015
Efficient production of reuterin from glycerol by magnetically immobilized Lactobacillus reuterin, Liu FX, Yu B*, 2015
Major role of NAD-dependent lactate dehydrogenases in high optically pure L-lactic acid production by thermophilic Bacillus coagulans, Wang LM#, Cai YM#, Zhu LF, Guo HL, Yu B*, 2014
Bacillus sp. strain P38: an efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural, Peng LL, Wang LM, Che CC, Yang G, Yu B*, Ma YH, 2013
Efficient production of polymer-grade D-lactate by Sporolactobacillus laevolacticus DSM442 with agricultural waste cottonseed as the sole nitrogen source, Li Y, Wang LM, Ju JS, Yu B*, Ma YH, 2013
聚合级L-乳酸的非粮生物质发酵研究进展, 于波*，曾艳，姜旭，王丽敏，马延和, 2013

Extremophiles Industrial Application Screening Bio-Based Chemicals Microbial Synthesis Industrial Development Plant-Derived Compounds Biotechnology Synthetic Biology Metabolic Engineering

Lijie Cui - Shanghai Normal University

Xianqing Huang - Shanghai Jiao Tong University

Min Qian - East China Normal University

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