Professor | 于波 | 数字化转型顾问

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Name	于波
Contact Information	yub@im.ac.cn
Language ability	中文, 英语, 德语
Province	北京

Upload Avatar (500 x 500)

Name

于波

Contact Information

yub@im.ac.cn

Language ability

中文, 英语, 德语

Province

北京

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2001-09--2006-06 博士: 山东大学 2008-2010 博士后: 德国Helmholtz感染研究中心 2008-2010 博士后: 德国汉堡工业大学
Work Experience	2006-2008 - 中国科学院微生物研究所 - 助理研究员 2010-2016 - 中国科学院微生物研究所 - 副研究员、青年研究组长 2016- - 中国科学院微生物研究所 - 研究员、研究组长

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2001-09--2006-06 博士: 山东大学
2008-2010 博士后: 德国Helmholtz感染研究中心
2008-2010 博士后: 德国汉堡工业大学

Work Experience

2006-2008 - 中国科学院微生物研究所 - 助理研究员
2010-2016 - 中国科学院微生物研究所 - 副研究员、青年研究组长
2016- - 中国科学院微生物研究所 - 研究员、研究组长

Areas of Focus	具有工业应用潜力的极端微生物的筛选与应用生物基平台化学品的微生物合成技术与产业化开发植源化合物的微生物合成
Publications	One major facilitator superfamily transporter is responsible for propionic acid tolerance in Pseudomonas putida KT2440, Ma C, Mu QX, Xue YB, Xue YF, Yu B, Ma YH, 2020 Bio-production of high-purity propionate by engineering L-threonine degradation pathway in Pseudomonas putida, Ma C, Mu QX, Wang L, Shi YN, Zhu LF, Zhang SS, Xue YF, Tao Y, Ma YH, Yu B, 2020 Enhanced ε-poly-L-lysine production by the synergistic effect of ε-poly-L-lysine synthetase overexpression and citrate in Streptomyces albulus, Wang AX, Tian WZ, Cheng L, Xu YQ, Wang XW, Qin JY, Yu B, 2020 Biocatalytic production of D-p-hydroxyphenylglycine by optimizing protein expression and cell wall engineering in Escherichia coli, Liu Y, Zhu LF, Qi WP, Yu B, 2019 Biodetoxification of fungal mycotoxins zearalenone by engineered probiotic bacterium Lactobacillus reuteri with surface-displayed lactonohydrolase, Liu FX, Malaphan M, Xing FG, Yu B, 2019 A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts, Zheng Y#, Meng FK#, Zhu ZH, Wei WJ, Sun Z, Chen JC, Yu B, Lou CB, Chen GQ, 2019 Elucidating the role and regulation of a lactate permease as lactate transporter in Bacillus coagulans DSM1, Wang Y, Zhang CL, Liu GX, Ju JS, Yu B, Wang LM, 2019 Biotechnological routes for transglutaminase production: recent achievements, perspectives and limits, Wang LM, Yu B, Wang RX, Xie JC, 2018 Reconstructing biosynthetic pathway of the plant-derived cancer chemopreventive-precursor glucoraphanin in Escherichia coli, Yang H, Liu FX, Li Y, Yu B, 2018 Biosynthesis of the high-value plant secondary product benzyl isothiocyanate via functional expression of multiple heterologous enzymes in E. coli, Liu FX, Yang H, Wang LM, Yu B, 2016 Efficient production of enantiomerically pure D-phenyllactate from phenylpyruvate by structure-guided design of an engineered D-lactate dehydrogenase, Wang M#, Zhu LF#, Xu XL, Wang LM, Yin RC, Yu B, 2016 Diammonium phosphate stimulates transcription of L-lactate dehydrogenase leading to increased L-lactate production in the thermotolerant Bacillus coagulans strain, Sun LF, Li YF, Wang LM, Wang YP, Yu B, 2016 Efficient biodegradation of chlorophenols in aqueous phase by magnetically immobilized aniline-degrading Rhodococcus rhodochrous strain, Hou JF, Liu FX, Wu N, Ju JS, Yu B, 2016 Fermentative production of enantiomerically pure S-1,2-propanediol from glucose by engineered E. coli strain, Zhu LF#, Guan XC#, Xie NZ, Wang LM, Yu B, Ma YH, 2016 NADP+-preferring D-lactate dehydrogenase from Sporolactobacillus inulinus, Zhu LF, Xu XL, Wang LM, Dong H, Yu B, Ma YH, 2015 Efficient production of reuterin from glycerol by magnetically immobilized Lactobacillus reuterin, Liu FX, Yu B, 2015 Major role of NAD-dependent lactate dehydrogenases in high optically pure L-lactic acid production by thermophilic Bacillus coagulans, Wang LM#, Cai YM#, Zhu LF, Guo HL, Yu B, 2014 Bacillus sp. strain P38: an efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural, Peng LL, Wang LM, Che CC, Yang G, Yu B*, Ma YH, 2013 Efficient production of polymer-grade D-lactate by Sporolactobacillus laevolacticus DSM442 with agricultural waste cottonseed as the sole nitrogen source

Areas of Focus

具有工业应用潜力的极端微生物的筛选与应用
生物基平台化学品的微生物合成技术与产业化开发
植源化合物的微生物合成

Publications

One major facilitator superfamily transporter is responsible for propionic acid tolerance in Pseudomonas putida KT2440, Ma C, Mu QX, Xue YB, Xue YF, Yu B*, Ma YH*, 2020
Bio-production of high-purity propionate by engineering L-threonine degradation pathway in Pseudomonas putida, Ma C, Mu QX, Wang L, Shi YN, Zhu LF, Zhang SS, Xue YF, Tao Y, Ma YH*, Yu B*, 2020
Enhanced ε-poly-L-lysine production by the synergistic effect of ε-poly-L-lysine synthetase overexpression and citrate in Streptomyces albulus, Wang AX, Tian WZ, Cheng L, Xu YQ, Wang XW, Qin JY, Yu B, 2020
Biocatalytic production of D-p-hydroxyphenylglycine by optimizing protein expression and cell wall engineering in Escherichia coli, Liu Y, Zhu LF, Qi WP, Yu B*, 2019
Biodetoxification of fungal mycotoxins zearalenone by engineered probiotic bacterium Lactobacillus reuteri with surface-displayed lactonohydrolase, Liu FX, Malaphan M, Xing FG, Yu B*, 2019
A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts, Zheng Y#, Meng FK#, Zhu ZH, Wei WJ, Sun Z, Chen JC, Yu B*, Lou CB*, Chen GQ*, 2019
Elucidating the role and regulation of a lactate permease as lactate transporter in Bacillus coagulans DSM1, Wang Y, Zhang CL, Liu GX, Ju JS, Yu B*, Wang LM*, 2019
Biotechnological routes for transglutaminase production: recent achievements, perspectives and limits, Wang LM*, Yu B, Wang RX, Xie JC, 2018
Reconstructing biosynthetic pathway of the plant-derived cancer chemopreventive-precursor glucoraphanin in Escherichia coli, Yang H, Liu FX, Li Y*, Yu B*, 2018
Biosynthesis of the high-value plant secondary product benzyl isothiocyanate via functional expression of multiple heterologous enzymes in E. coli, Liu FX, Yang H, Wang LM, Yu B*, 2016
Efficient production of enantiomerically pure D-phenyllactate from phenylpyruvate by structure-guided design of an engineered D-lactate dehydrogenase, Wang M#, Zhu LF#, Xu XL, Wang LM, Yin RC*, Yu B*, 2016
Diammonium phosphate stimulates transcription of L-lactate dehydrogenase leading to increased L-lactate production in the thermotolerant Bacillus coagulans strain, Sun LF, Li YF, Wang LM, Wang YP, Yu B*, 2016
Efficient biodegradation of chlorophenols in aqueous phase by magnetically immobilized aniline-degrading Rhodococcus rhodochrous strain, Hou JF, Liu FX, Wu N, Ju JS, Yu B*, 2016
Fermentative production of enantiomerically pure S-1,2-propanediol from glucose by engineered E. coli strain, Zhu LF#, Guan XC#, Xie NZ, Wang LM, Yu B*, Ma YH, 2016
NADP+-preferring D-lactate dehydrogenase from Sporolactobacillus inulinus, Zhu LF, Xu XL, Wang LM, Dong H*, Yu B*, Ma YH, 2015
Efficient production of reuterin from glycerol by magnetically immobilized Lactobacillus reuterin, Liu FX, Yu B*, 2015
Major role of NAD-dependent lactate dehydrogenases in high optically pure L-lactic acid production by thermophilic Bacillus coagulans, Wang LM#, Cai YM#, Zhu LF, Guo HL, Yu B*, 2014
Bacillus sp. strain P38: an efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural, Peng LL, Wang LM, Che CC, Yang G, Yu B*, Ma YH, 2013
Efficient production of polymer-grade D-lactate by Sporolactobacillus laevolacticus DSM442 with agricultural waste cottonseed as the sole nitrogen source

极端微生物工业应用筛选生物基化学品微生物合成产业化开发植源化合物生物技术合成生物学代谢工程

芦银华 - 上海师范大学

崔丽洁 - 上海师范大学

黄显清 - 上海交通大学

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