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Haibo Zhou
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English, Dutch
Crispr
Gene Editing
Neuroscience
Neurodegenerative Diseases
Rna Editing
Extracellular Vesicles
Astrocytes
Tmem164
Alzheimer'S Disease
Parkinson'S Disease
Areas of Focus
- Gene Editing Technology Development
- Treatment of Nervous System Diseases
Work Experience
- 2020-06~Present - Chinese Academy of Sciences, Center for Excellence in Brain Science and Intelligence Technology - Researcher
- 2015-04~2020-05 - Chinese Academy of Sciences, Center for Excellence in Brain Science and Intelligence Technology - Postdoctoral Researcher
- 2012-09~2014-11 - Erasmus University Rotterdam - PhD
- 2010-09~2012-08 - Erasmus University Rotterdam - Master's
- 2005-09~2009-07 - Jilin University - Bachelor's
Academic Background & Achievements
- 2012-09--2014-11 PhD: Erasmus University Rotterdam
- 2010-09--2012-08 Master's: Erasmus University Rotterdam
- 2005-09--2009-07 Bachelor's: Jilin University
Publications
- Generation of rat forebrain tissues in mice, Haibo Zhou, 2024
- Engineered Extracellular Vesicle-Delivered CRISPR/CasRx as a Novel RNA Editing Tool, Haibo Zhou, 2023
- Alleviating symptoms of neurodegenerative disorders by astrocyte-specific overexpression of TMEM164 in mice, Haibo Zhou, 2023
- Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAs, Haibo Zhou, 2021
- Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos, Haibo Zhou, 2021
- Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice, Haibo Zhou, 2020
- CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration, Haibo Zhou, 2020
- Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis, Haibo Zhou, 2019
- In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice, Haibo Zhou, 2018
- Homology-mediated end joining-based targeted integration using crispr/cas9, Haibo Zhou, 2017
- Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice, Haibo Zhou, 2016
- Differential Purkinje cell simple spike activity and pausing behavior related to cerebellar modules, Haibo Zhou, 2015
- Cerebellar modules operate at different frequencies, Haibo Zhou, 2014
- Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis, Haibo Zhou, 2014
