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Yi Xiao Zhang
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Cryo-Electron Microscopy
Cell Mechanotransduction
Neurodegenerative Diseases
Ion Channels
Molecular Mechanisms
Protein Structures
Membrane Tension
Human Tsen Endonuclease
Histone Pre-Mrna
G-Protein
Areas of Focus
- Cryo-Electron Microscopy
- Cell Mechanotransduction
- Neurodegenerative Diseases
Work Experience
- 2015-10 to 2021-02 - Rockefeller University - Postdoctoral Researcher, Assistant Researcher
- 2010-09 to 2015-06 - Tsinghua University, School of Life Sciences - PhD
- 2006-09 to 2010-07 - Sichuan University, School of Life Sciences - Bachelor
Academic Background & Achievements
- 2010-09 to 2015-06 PhD: Tsinghua University, School of Life Sciences
- 2006-09 to 2010-07 Bachelor: Sichuan University, School of Life Sciences
Publications
- Mechanical activation opens a lipid-lined pore in OSCA ion channels, Yi Xiao Zhang, 2024
- Recognition and cleavage mechanism of intron-containing pre-tRNA by human TSEN endonuclease complex, Yi Xiao Zhang, 2023
- MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels, Yi Xiao Zhang, 2023
- Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction, Yi Xiao Zhang, 2021
- Visualizing the mechanosensitive ion channel MscS under membrane tension., Yi Xiao Zhang, 2021
- Structure of an active human histone pre-mRNA 3′-end processing machinery, Yi Xiao Zhang, 2020
- Structural Insights into the Human Pre-mRNA 3 '-End Processing Machinery, Yi Xiao Zhang, 2020
- Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound β1-Adrenergic Receptor, Yi Xiao Zhang, 2020
- Cryo-Electron Microscopy Structure of the alpha IIb beta 3-Abciximab Complex, Yi Xiao Zhang, 2020
- A binding-block ion selective mechanism revealed by a Na/K selective channel, Yi Xiao Zhang, 2018
- Molecular basis for the recognition of the human AAUAAA polyadenylation signal, Yi Xiao Zhang, 2018
- Architecture of the human PI4KIII alpha lipid kinase complex, Yi Xiao Zhang, 2017
- Structural basis for interaction of a cotranslational chaperone with the eukaryotic ribosome, Yi Xiao Zhang, 2014
