Professor | Zhi Ke | Asia Growth Partners

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Name	Zhi Ke
Contact Information	zk.zi@siat.ac.cn
Language ability	Chinese, German, English
Province	Guangdong

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Name

Zhi Ke

Contact Information

zk.zi@siat.ac.cn

Language ability

Chinese, German, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2005-08--2008-10 PhD: Humboldt University 2002-09--2005-07 Master's: Tsinghua University 1998-09--2002-06 Bachelor's: South-Central University for Nationalities
Work Experience	2022-07~Present - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Researcher 2019-01~2022-06 - German Federal Institute for Risk Assessment - Tenured Scientist 2014-05~2018-12 - Max Planck Institute for Molecular Genetics - Researcher, Group Leader (PI) 2009-11~2014-04 - University of Freiburg - Project Leader 2009-01~2009-10 - Humboldt University - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2005-08--2008-10 PhD: Humboldt University
2002-09--2005-07 Master's: Tsinghua University
1998-09--2002-06 Bachelor's: South-Central University for Nationalities

Work Experience

2022-07~Present - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Researcher
2019-01~2022-06 - German Federal Institute for Risk Assessment - Tenured Scientist
2014-05~2018-12 - Max Planck Institute for Molecular Genetics - Researcher, Group Leader (PI)
2009-11~2014-04 - University of Freiburg - Project Leader
2009-01~2009-10 - Humboldt University - Postdoctoral Researcher

Areas of Focus	Systems Biology Bioinformatics
Publications	Liebig’s law of the minimum in the TGF-β/SMAD pathway, Corresponding Author, 2024 Machine learning unveils RNA polymerase II binding as a predictor for SMAD2‐dependent transcription dynamics in response to Actvin signalling, Corresponding Author, 2024 PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes, 6th Author, 2023 Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications, 3rd Author, 2020 Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest, Corresponding Author, 2020 Molecular Engineering of the TGF-β Signaling Pathway, Corresponding Author, 2019 eDetect: A Fast Error Detection and Correction Tool for Live Cell Imaging Data Analysis, Corresponding Author, 2019 Tissue-Specific Chk1 Activation Determines Apoptosis by Regulating the Balance of p53 and p21, Corresponding Author, 2019 Spatiotemporal Control of TGF- β Signaling with Light, Corresponding Author, 2018 Quantitative analysis of transient and sustained transforming growth factor‐β signaling dynamics, Corresponding Author, 2011 SBML-PET-MPI: a parallel parameter estimation tool for Systems Biology Markup Language based models, Corresponding Author, 2011 Time-Dependent Quantitative Multicomponent Control of the G(1)-S Network by the Stress-Activated Protein Kinase Hog1 upon Osmostress, 2nd Author, 2011

Areas of Focus

Systems Biology
Bioinformatics

Publications

Liebig’s law of the minimum in the TGF-β/SMAD pathway, Corresponding Author, 2024
Machine learning unveils RNA polymerase II binding as a predictor for SMAD2‐dependent transcription dynamics in response to Actvin signalling, Corresponding Author, 2024
PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes, 6th Author, 2023
Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications, 3rd Author, 2020
Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest, Corresponding Author, 2020
Molecular Engineering of the TGF-β Signaling Pathway, Corresponding Author, 2019
eDetect: A Fast Error Detection and Correction Tool for Live Cell Imaging Data Analysis, Corresponding Author, 2019
Tissue-Specific Chk1 Activation Determines Apoptosis by Regulating the Balance of p53 and p21, Corresponding Author, 2019
Spatiotemporal Control of TGF- β Signaling with Light, Corresponding Author, 2018
Quantitative analysis of transient and sustained transforming growth factor‐β signaling dynamics, Corresponding Author, 2011
SBML-PET-MPI: a parallel parameter estimation tool for Systems Biology Markup Language based models, Corresponding Author, 2011
Time-Dependent Quantitative Multicomponent Control of the G(1)-S Network by the Stress-Activated Protein Kinase Hog1 upon Osmostress, 2nd Author, 2011

Systems Biology: Computational Biology Modeling Simulation Network Analysis Pathway Analysis Dynamic Systems Biological Systems Quantitative Biology Systems Theory Integrative Biology Bioinformatics: Data Analysis Genomics Proteomics Sequence Alignment Machine Learning Computational Tools Biological Databases Algorithm Development Transcriptomics Structural Biology

Yong Zhang - Tongji University

Xiaocui Xu - Tongji University

Yanping Zhang - Tongji University

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